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Credit Name
Almeida, Luís Pereira de
 
Name
Almeida, Luís Pereira de
 
Variants
Almeida, Luís Fernando Morgado Pereira de
Almeida, Luís
Almeida, Luís Pereira de
Almeida, L. P.
 
 
Email
luispa@ci.uc.pt
 
 
 
Ciência ID
 
Researcher ID
 
Status
UC Researcher
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Publications

Results 1-146 of 146 (Search time: 0.001 seconds).

Issue DateTitleAuthor(s)TypeAccess
1Sep-2015Adeno associated viral vectors for brain gene therapyRodrigues, Pedro dos SantosotheropenAccess
2Jul-2014Administração intranasal para doenças do cérebroCosta, Ana Catarina de SousaotheropenAccess
3Oct-2008Allele-specific RNA silencing of mutant ataxin-3 mediates neuroprotection in a rat model of Machado-Joseph diseaseAlves, Sandro ; Nascimento-Ferreira, Isabel ; Auregan, Gwennaëlle ; Hassig, Raymonde ; Dufour, Noëlle ; Brouillet, Emmanuel ; Lima, Maria C. Pedroso de ; Hantraye, Philippe ; Almeida, Luís Pereira de ; Déglon, Nicole articleopenAccess
47-Oct-2019Alpha-synuclein in extracellular vesiclesMarques, Andreia Raquel MinasmasterThesisembargoedAccess
515-Oct-2018Analytical Quality By Design To Characterize Inhalation ProductsGaspar, Joana Rita Mendes masterThesisopenAccess
62003Application of non-local density functionals to clusters, surfaces and voidsFiolhais, Carlos ; Almeida, Luís articleopenAccess
74-Mar-2019Assessing the putative role of mesenchymal stromal cells’ effectors in Machado-Joseph diseaseBarros, Maria Inês Veiga de Almeida masterThesisembargoedAccess
816-May-2014Assessment of JC polyomavirus in normal colorectal mucosa, hyperplastic polyps and sporadic adenomas and adenocarcinomas in a Portuguese population and its association with cancer developmentCoelho, Tatiana Rasteiro doctoralThesisopenAccess
929-Nov-2021Autophagy in Spinocerebellar ataxia type 2, a dysregulated pathway, and a target for therapyMarcelo, Adriana ; Afonso, Inês T.; Afonso-Reis, Ricardo; Brito, David V. C.; Costa, Rafael G.; Rosa, Ana; Alves-Cruzeiro, João ; Ferreira, Benedita; Henriques, Carina; Nobre, Rui J. ; Matos, Carlos A.; Almeida, Luís Pereira de ; Nóbrega, Clévio articleopenAccess
1031-Mar-2016Autophagy in the hypothalamus: role of Neuropeptide Y and impact on Synaptic PlasticityRocha, Mariana Botelho da doctoralThesisopenAccess
112014Biomedical applications using ionic liquidsVieira, Nicole Sofia MorgadomasterThesisopenAccess
1211-Dec-2020Brain-enriched plasma-derived extracellular vesicles as biomarkers for Machado-Joseph diseasePinto, Maria Manuel Martins masterThesisembargoedAccess
13Sep-2016Cachexia in patients with head and neck cancer undergoing radiotherapy or concurrent chemoradiotherapy : characterization, molecular mechanisms and relationshipsPedro, Nicole Sónia NetomasterThesisembargoedAccess
142013Caffeine and adenosine A 2A receptor inactivation decrease striatal neuropathology in a lentiviral-based model of Machado–Joseph diseaseGonçalves, Nélio ; Simões, Ana T. ; Cunha, Rodrigo A. ; Almeida, Luís Pereira de articleopenAccess
1511-May-2016Caloric restriction blocks neuropathology and motor deficits in Machado-Joseph disease mouse models through SIRT1 pathwayCunha-Santos, Janete ; Duarte-Neves, Joana ; Carmona, Vitor ; Guarente, Leonard; Almeida, Luís Pereira de ; Cavadas, Cláudia articleopenAccess
162016Caloric restriction stimulates autophagy in rat cortical neurons through neuropeptide Y and ghrelin receptors activationFerreira-Marques, Marisa; Aveleira, Célia A. ; Carmo-Silva, Sara; Botelho, Mariana ; Pereira de Almeida, Luís ; Cavadas, Cláudia articleopenAccess
172014Calpain inhibition reduces ataxin-3 cleavage alleviating neuropathology and motor impairments in mouse models of Machado-Joseph diseaseSimões, Ana Teresa ; Gonçalves, Nélio ; Nobre, Rui Jorge ; Duarte, Carlos Bandeira ; Almeida, Luís Pereira de articleembargoedAccess
1827-Jul-2012Calpain-mediated proteolysis of ataxin-3 in Machado-Joseph diseaseSimões, Ana Teresa doctoralThesisembargoedAccess
192012Calpastatin-mediated inhibition of calpains in the mouse brain prevents mutant ataxin 3 proteolysis, nuclear localization and aggregation, relieving Machado–Joseph diseaseSimões, Ana T. ; Gonçalves, Nélio ; Koeppen, Arnulf ; Déglon, Nicole ; Kügler, Sebastian ; Duarte, Carlos Bandeira ; Almeida, Luís Pereira de articleopenAccess
2025-Oct-2013Caracterização do perfil genómico do carcinoma pulmonarPortovedo, Sérgio Filipe JesusmasterThesisopenAccess
21Sep-2013Caraterização do perfil genómico do carcinoma pulmonarPortovedo, Sérgio Filipe de JesusmasterThesisopenAccess
2222-Feb-2012Cationic Nanoparticles: Friend or Foe? Deciphering the mechanisms of cell death induced by cationic nanoparticlesBexiga, Mariana Godinho doctoralThesisclosedAccess
232022Cerebellar morphometric and spectroscopic biomarkers for Machado-Joseph DiseaseMiranda, Catarina Oliveira ; Nobre, Rui Jorge ; Paiva, Vítor Hugo ; Duarte, João Valente ; Castelhano, João ; Petrella, Lorena Itati ; Sereno, José ; Santana, Magda ; Afonso, Sónia ; Januário, Cristina ; Castelo Branco, Miguel ; Almeida, Luís Pereira de articleopenAccess
242013Cerebrospinal fluid biomarkers for neurodegenerative disordersVideira, Rita Margarida Almeida Santos masterThesisembargoedAccess
258-Oct-2019Cervical cancer screening: self-sampling as a complement to the conventional methodPereira, Sara da Graça MarquesmasterThesisembargoedAccess
262013Células estaminais pluripotentes induzidas no estudo de mecanismos de doença e avaliação de novas terapiasCorreia, Liliana dos Santos TavaresmasterThesisembargoedAccess
272013Clinical trials: portuguese overview, perspectives and competitiveness challengesOliveira, Maria João Nunes de masterThesisopenAccess
282003Comparative study of GDNF delivery systems for the CNS: polymer rods, encapsulated cells, and lentiviral vectorsBensadoun, Jean-Charles ; Pereira de Almeida, Luis ; Fine, Eric G. ; Tseng, Jack L. ; Déglon, Nicole ; Aebischer, Patrick articleopenAccess
292008Complete genotyping of mucosal human papillomavirus using a restriction fragment length polymorphism analysis and an original typing algorithmNobre, Rui Jorge ; Almeida, Luís Pereira de ; Martins, Teresa C. articleopenAccess
3029-Jul-2019A Computational Method to Predict the Combinatory Effect of Drugs in CancerFilipe, Pedro Matos Pinto Santos masterThesisembargoedAccess
315-Dec-2017Control of Huntington's Disease-Associated Phenotypes by the Striatum-Enriched Transcription Factor Foxp2Hachigian, Lea J.; Carmona, Vitor ; Fenster, Robert J.; Kulicke, Ruth; Heilbut, Adrian; Sittler, Annie; Almeida, Luís Pereira de ; Mesirov, Jill P.; Gao, Fan; Kolaczyk, Eric D.; Heiman, MyriamarticleopenAccess
32Jul-2016CRISPR/CAS9 : uma ferramenta de edição genética para investigação e novas terapiasRamos, António David RufinootheropenAccess
33Jan-2014Custo-efetividade da utilização de um teste farmacogenético para o Alopurinol em doentes portugueses diagnosticados com gotaAraújo, Maurício AlvesmasterThesisopenAccess
3417-Feb-2017Delaying neurodegeneration through caloric restriction approaches: From mechanisms to molecular therapySantos, Janete Antónia da Cunha doctoralThesisembargoedAccess
3515-Jan-2000Density-functional versus wave-function methods: Toward a benchmark for the jellium surface energyYan, Zidan ; Perdew, John P. ; Kurth, Stefan ; Fiolhais, Carlos ; Almeida, Luís articleopenAccess
3617-Dec-2020Development of Single-Step Affinity Chromatography Protocols for the Purification of Adeno-Associated Viral Vectors.Carreiras, Rafael BaganhamasterThesisembargoedAccess
3724-Feb-2017Défice Cognitivo Ligeiro e Doença de Alzheimer: as diferenças numa perspetiva proteómicaFreitas, Ana Karolina Seco das Neves masterThesisembargoedAccess
3827-Sep-2019A different perspective of circulatory biomarkers in neurodegenerative diseases: focus on serum high molecular weight fractionRosado, Miguel Maria Varandas Anão masterThesisembargoedAccess
39Mar-2018Dipeptidyl peptidase IV (DPP-IV) inhibition prevents fibrosis in adipose tissue of obese miceMarques, Ana Patrícia; Cunha-Santos, Janete; Leal, Helena; Sousa-Ferreira, Lígia ; Pereira de Almeida, Luís ; Cavadas, Cláudia ; Rosmaninho-Salgado, Joana articleopenAccess
4027-Jul-2016Dissecting the pathogenesis of Machado-Joseph Disease in a new human disease model derived from induced pluripotent stem cellsOnofre, Isabel Maria dos Santos doctoralThesisembargoedAccess
412005Effect of age and gender on the pharmacokinetics of eslicarbazepine acetateSoares-da-Silva, Patricio ; Almeida, Luís ; Falcão, Amílcar ; Maia, Joana articleopenAccess
422005EFFECT OF ESLICARBAZEPINE ACETATE ON THE STEADYSTATE PHARMACOKINETICS OF DIGOXIN IN HEALTHY SUBJECTSMaia, Joana ; Almeida, Luís ; Vaz-da-Silva, Manuel ; Soares, Eva ; Tavares, Susana ; Falcão, Amílcar ; Soares-da-Silva, Patrício articleopenAccess
431-Jun-2011Effect of Food on the Pharmacokinetic Profile of Etamicastat (BIA 5-453)Vaz-da-Silva, Manuel ; Nunes, Teresa ; Rocha, José F. ; Falcão, Amílcar ; Almeida, Luis ; Soares-da-Silva, Patricio articleopenAccess
442007Effect of Gender on the Pharmacokinetics of Eslicarbazepine Acetate (BIA 2-093), a New Voltage-gated Sodium Channel BlockerFalcão, Amílcar ; Maia, Joana ; Almeida, Luís ; Mazur, Dago ; Gellert, Manfred ; Soares-da-Silva, Patrício articleopenAccess
452005Effect of preventive and regressive isosorbide 5-mononitrate treatment on catecholamine levels in plasma, platelets, adrenals, left ventricle and aorta in cyclosporin A-induced hypertensive ratsReis, Flávio ; Rocha, Luís ; Ponte, Luísa ; Alcobia, Teresa ; Almeida, Luís ; Costa-Almeida, Carlos ; Teixeira, Frederico articleopenAccess
46Sep-2013Engenharia de tecidos: válvulas cardíacasAlves, Ana Rita CarvalhomasterThesisopenAccess
472005ESLICARBAZEPINE ACETATE PHARMACOKINETICS AFTER SINGLE AND REPEATED DOSES IN HEALTHY SUBJECTSVaz-da-Silva, Manuel ; Nunes, Teresa ; Soares, Eva ; Rocha, José Francisco ; Tavares, Susana ; Falcão, Amílcar ; Almeida, Luís ; Soares-da-Silva, Patricio articleopenAccess
488-Oct-2019Establishment and Characterization of Human Pluripotent Stem Cells derived Brain OrganoidsBrás, João Pedro SantosmasterThesisembargoedAccess
492015Estudo da potencial toxicidade do processo de silenciamento da ataxina 3 mutante humana mediado por shRNA lentiviralCodêsso, José Miguel Antunes masterThesisopenAccess
502015Evaluation of the potential anti-inflammatory and neuroprotective effect of a FAAH inhibitor in glaucome modelsMartins, Joana Margarida Cardoso SerramasterThesisembargoedAccess
51Sep-2015Exossomas e o seu papel na comunicação intercelularSilva, Micaela José daotheropenAccess
5213-Nov-2021Extracellular Vesicles Physiological Role and the Particular Case of Disease-Spreading Mechanisms in Polyglutamine DiseasesMoreira, Ricardo ; Mendonça, Liliana Simões ; Almeida, Luís Pereira de articleopenAccess
5322-Jun-2016Fibroblasts of Machado Joseph Disease patients reveal autophagy impairmentOnofre, Isabel ; Mendonça, Nuno ; Lopes, Sara ; Nobre, Rui J. ; Melo, Joana Barbosa ; Carreira, Isabel Marques ; Januário, Cristina ; Gonçalves, António Freire ; Almeida, Luís Pereira de articleopenAccess
545-Mar-2014Fluoxetine Induces Proliferation and Inhibits Differentiation of Hypothalamic Neuroprogenitor Cells In VitroSousa-Ferreira, Lígia ; Aveleira, Célia ; Botelho, Mariana ; Álvaro, Ana Rita ; Almeida, Luís Pereira de ; Cavadas, Cláudia articleopenAccess
5521-Oct-2021Gene editing technologies to Machado-Joseph diseaseLopes, Sara Isabel MonteirodoctoralThesisembargoedAccess
562015Gene therapy-based strategies for glioblastoma towards chemosensitization : use of gemini surfactants as drug delivery systemsCruz, Ana Rita Queirós damasterThesisembargoedAccess
5729-Nov-2013Gene transfer approaches to study the role of adenosine A2A receptors in Machado-Joseph diseaseGonçalves, Nélio da Mota doctoralThesisopenAccess
58May-2018Generation and characterization of a human iPS cell line from a patient-related control to study disease mechanisms associated with DAND5 p.R152H alterationPars, Selin; Cristo, Fernando; Inácio, José M.; Rosas, Graça; Carreira, Isabel Marques ; Melo, Joana Barbosa ; Mendes, Patrícia; Martins, Duarte Saraiva; Almeida, Luís Pereira de ; Maio, José; Anjos, Rui ; Belo, José A.articleopenAccess
592017Generation of human iPSC line from a patient with laterality defects and associated congenital heart anomalies carrying a DAND5 missense alterationCristo, Fernando; Inácio, José M; Rosas, Graça; Carreira, Isabel Marques ; Melo, Joana Barbosa ; Almeida, Luís Pereira de ; Mendes, Patrícia; Martins, Duarte Saraiva; Maio, José; Anjos, Rui ; Belo, José A.articleopenAccess
602021Highly Porous Composite Scaffolds Endowed with Antibacterial Activity for Multifunctional Grafts in Bone RepairNeto, Ana S.; Pereira, Patrícia ; Fonseca, Ana C. ; Dias, Carla ; Almeida, Mariana C. ; Barros, Inês ; Miranda, Catarina O. ; Almeida, Luís P. de ; Morais, Paula V. ; Ferreira, José M. F.articleopenAccess
612-Oct-2021Highly Specific Blood-Brain Barrier Transmigrating Single-Domain Antibodies Selected by an In Vivo Phage Display ScreeningAguiar, Sandra Isabel; Dias, Joana N. R.; André, Ana Santos; Silva, Marta Lisete; Martins, Diana; Carrapiço, Belmira; Castanho, Miguel A. R. B. ; Carriço, João; Cavaco, Marco; Gaspar, Maria Manuela; Nobre, Rui J. ; Almeida, Luís Pereira de ; Oliveira, Soraia; Gano, Lurdes; Correia, João D. G.; Barbas, Carlos; Gonçalves, João; Neves, Vera; Aires-da-Silva, FredericoarticleopenAccess
622014A hipótese do citocromo P450 na etiologia do suicídioMondego, Sandra Patrícia SantosmasterThesisopenAccess
6311-Jun-2018Identification of the toxic fragment of ataxin-3 protein in Machado-Joseph diseaseSimões, Ana Teresa Antunes masterThesisembargoedAccess
642012Immobilization of metalloproteins for biotechnological applicationsGenebra, Tânia Isabel RodriguesmasterThesisembargoedAccess
6510-May-2023In Vitro Evaluation of Biphasic Calcium Phosphate Scaffolds Derived from Cuttlefish Bone Coated with Poly(ester urea) for Bone Tissue RegenerationPereira, Patrícia ; Neto, Ana S.; Rodrigues, Ana Sofia ; Barros, Inês ; Miranda, Catarina O. ; Santos, João Ramalho ; Almeida, Luís Pereira de ; Ferreira, José M. F.; Coelho, Jorge ; Fonseca, Ana C. articleopenAccess
6619-Oct-2018Ins2Akita mouse as a model of diabetic retinopathy: angiogenic and inflammatory characterization for selection of therapeutic targetsSilva, Maria Carolina Sousa masterThesisembargoedAccess
6722-Apr-2022Investigating transcriptional modifications of the autophagy pathway in Machado-Joseph DiseaseFerreira, Ana Cristina Lopes VasconcelosdoctoralThesisembargoedAccess
683-Oct-2018Investigation of mutant ataxin-3 spreading in Machado-Joseph DiseaseMoreira, Ricardo Gomes masterThesisembargoedAccess
6921-Feb-2003Lentiviral-basead gene delivery approaches for therapeutic and functional studies in Huntington's disease.Almeida, Luís Fernando Morgado Pereira de doctoralThesisembargoedAccess
707-Jul-2021Living Proof of Activity of Extracellular Vesicles in the Central Nervous SystemMahjoum, Shadi; Rufino-Ramos, David; Almeida, Luís Pereira de ; Broekman, Marike L. D.; Breakefield, Xandra O.; van Solinge, Thomas S.articleopenAccess
712004Long-term lentiviral-mediated expression of ciliary neurotrophic factor in the striatum of Huntington's disease transgenic miceZala, Diana ; Bensadoun, Jean-Charles ; Pereira de Almeida, Luis ; Leavitt, Blair R. ; Gutekunst, Claire-Anne ; Aebischer, Patrick ; Hayden, Michael R. ; Déglon, Nicole articleopenAccess
7217-Oct-2017Machado-Joseph Disease: Understanding Epidemiologic and Clinical Features and a Potential New Therapeutic EntitySilva, Patrick Joel da masterThesisembargoedAccess
732020Mesenchymal Stromal Cells' Therapy for Polyglutamine Disorders: Where Do We Stand and Where Should We Go?Barros, Inês ; Marcelo, Adriana ; Silva, Teresa P. ; Barata, João ; Ramos, António David Rufino ; Almeida, Luís P. de ; Miranda, Catarina O. articleopenAccess
7416-Dec-2020MicroRNA profiling in human cell-based models of Machado-Joseph diseaseSantos, Maria Inês Nunes dosmasterThesisembargoedAccess
7525-Jul-2013MicroRNAs as molecular targets for non-viral gene therapy of glioblastoma: development of a lipid-based nanosystem for nucleic acid delivery to brain tumor cellsCosta, Pedro Miguel Coutinho da doctoralThesisopenAccess
762-May-2017MicroRNAs targeting Ataxin-3 mRNA in Machado-Joseph disease: from pathogenesis to therapyCarmona, Vitor Manuel Martins doctoralThesisembargoedAccess
776-Mar-2020miRNA-31 Improves Cognition and Abolishes Amyloid-β Pathology by Targeting APP and BACE1 in an Animal Model of Alzheimer's DiseaseBarros-Viegas, Ana Teresa ; Carmona, Vitor ; Ferreiro, Elisabete ; Guedes, Joana ; Cardoso, Ana Maria S. ; Cunha, Pedro ; Almeida, Luís Pereira de ; Oliveira, Catarina Resende de ; Magalhães, João Pedro de ; Peça, João ; Cardoso, Ana Luísa articleopenAccess
78Sep-2016miRNAs como biomarcadores e como estratégias de intervenção terapêutica na doença de AlzheimerMarques, Ana Lúcia CarreiraotheropenAccess
792020Mitochondrial and Redox Modifications in Huntington Disease Induced Pluripotent Stem Cells Rescued by CRISPR/Cas9 CAGs TargetingLopes, Carla ; Tang, Yang; Anjo, Sandra I. ; Manadas, Bruno ; Onofre, Isabel ; Almeida, Luís P. de ; Daley, George Q; Schlaeger, Thorsten M; Rego, Ana Cristina Carvalho articleopenAccess
801997Modeling dissolution of sparingly soluble multisized powdersAlmeida, Luís Pereira de ; Simões, Sérgio ; Brito, Paulo ; Portugal, António ; Figueiredo, Margarida articleopenAccess
812013Modelo Genético da Doença de Parkinson baseado na sobreexpressão da alfa-sinucleínaAnjos, Vanessa masterThesisembargoedAccess
822011Moderate long-term modulation of neuropeptide Y in hypothalamic arcuate nucleus induces energy balance alterations in adult ratsSousa-Ferreira, Lígia ; Garrido, Manuel Joaquim Marques ; Nascimento-Ferreira, Isabel ; Nóbrega, Clévio ; Carvalho, Ana dos Santos ; Álvaro, Ana Rita Costa Silva ; Salgado, Joana Rosmaninho ; Kaster, Manuella; Kügler, Sebastian ; Almeida, Luís Pereira de ; Cavadas, Cláudia articleopenAccess
832014Modulating actin dynamics during axon formation, growth and regeneration : the role of AdducinTavares, Carla Anita GomesmasterThesisopenAccess
842016Motor Dysfunctions and Neuropathology in Mouse Models of Spinocerebellar Ataxia Type 2: A Comprehensive ReviewAlves-Cruzeiro, João M. da Conceição ; Mendonça, Liliana ; Almeida, Luís Pereira de articleopenAccess
852014Multipotent mesenchymal stromal cells for Machado Joseph disease therapySilva, Teresa Maria Pereira da masterThesisopenAccess
8614-May-2019Neural Stem Cells of Parkinson's Disease Patients Exhibit Aberrant Mitochondrial Morphology and FunctionalityWalter, Jonas; Bolognin, Silvia; Antony, Paul M. A.; Nickels, Sarah L.; Poovathingal, Suresh K.; Salamanca, Luis; Magni, Stefano; Perfeito, Rita ; Hoel, Fredrik; Qing, Xiaobing; Jarazo, Javier; Arias-Fuenzalida, Jonathan; Ignac, Tomasz; Monzel, Anna S.; Gonzalez-Cano, Laura; Almeida, Luís Pereira de ; Skupin, Alexander; Tronstad, Karl J.; Schwamborn, Jens C.articleopenAccess
877-Jul-2020Neurofilaments in spinocerebellar ataxia type 3: blood biomarkers at the preataxic and ataxic stage in humans and miceWilke, Carlo; Haas, Eva; Reetz, Kathrin; Faber, Jennifer; Garcia-Moreno, Hector; Santana, Magda M. ; van de Warrenburg, Bart; Hengel, Holger; Lima, Manuela ; Filla, Alessandro; Durr, Alexandra; Melegh, Bela; Masciullo, Marcella; Infante, Jon; Giunti, Paola; Neumann, Manuela; de Vries, Jeroen; Almeida, Luís Pereira de ; Rakowicz, Maria; Jacobi, Heike; Schüle, Rebecca; Kaeser, Stephan A.; Kuhle, Jens; Klockgether, Thomas; Schöls, Ludger; Barro, Christian; Hübener-Schmid, Jeannette; Synofzik, MatthisarticleopenAccess
888-Feb-2021Neuropeptide Y (NPY) intranasal delivery alleviates Machado-Joseph diseaseDuarte-Neves, Joana ; Cavadas, Cláudia ; Almeida, Luís Pereira de articleopenAccess
8910-Feb-2016Neuropeptide Y gene transfer for neuroprotection in Machado-Joseph DiseaseNeves, Joana Filipa Duarte das doctoralThesisembargoedAccess
902001Neuroprotective Effect of a CNTF-Expressing Lentiviral Vector in the Quinolinic Acid Rat Model of Huntington's DiseaseAlmeida, L. Pereira de ; Zala, D. ; Aebischer, P. ; Déglon, N. articleopenAccess
912016Non-invasive viral-mediated gene therapy for Machado-Joseph diseaseSaraiva, Joana Isabel Rajão masterThesisembargoedAccess
9216-Feb-2016Non-viral silencing of Machado-Joseph disease through the systemic routeConceição, Mariana Oliveira doctoralThesisembargoedAccess
939-Aug-2023A Novel Genetic Variant in MBD5 Associated with Severe Epilepsy and Intellectual Disability: Potential Implications on Neural Primary CiliaMartins, Mariana ; Oliveira, Ana Rafaela ; Martins, Solange ; Vieira, José Pedro; Perdigão, Pedro ; Fernandes, Ana Rita; Almeida, Luís Pereira de ; Palma, Paulo Jorge ; Sequeira, Diana Bela ; Santos, João Miguel Marques ; Duque, Frederico ; Oliveira, Guiomar ; Cardoso, Ana Luísa ; Peça, João ; Seabra, Catarina Morais articleopenAccess
942015Novos sistemas para penetração da barreira hematoencefálica : das microbolhas à focagem de ultrassonsMartinho, Luís Miguel LopesmasterThesisembargoedAccess
95Jun-2014Oligonucleótidos antisense no tratamento de doenças do sistema nervoso centralAntunes, Telma Cristina HortaotheropenAccess
962015Optogenetics and biotechnology : production and in vitro characterization of Ab-Initio designed channelrhodopsin-2 mutantsPereira, João Miguel CalmeiromasterThesisopenAccess
97Sep-2016PERK inhibition role in Spinocerebellar ataxiasFerreira, Marco António RodriguesmasterThesisembargoedAccess
982009Pharmacokinetic-pharmacodynamic interaction between Nebicapone and controlled-release levodopa/benserazide:a single-center, fase I, double-blind, randomized, placebo-controlled, four-way crossover study in healthy subjectsNunes, Teresa ; Rocha, José F. ; Fernendes-Lopes, Carlos ; Costa, Raquel ; Torrão, Leonel ; Loureiro, Ana I. ; Falcão, Amílcar ; Vaz-da-Silva, Manuel ; Wright, Lyndon ; Almeida, Luís ; Soares-da-Silva, Patrício articleopenAccess
9927-Sep-2003Pharmacokinetic–pharmacodynamic interaction between BIA 3-202, a novel COMT inhibitor, and levodopa / benserazideSilveira, Pedro ; Vaz-da-Silva, Manuel ; Almeida, Luís ; Maia, Joana ; Falcão, Amílcar ; Loureiro, Ana ; Torrão, Leonel ; Machado, Rita ; Wright, Lyndon ; Soares-da-Silva, Patrício articleopenAccess
1002012Pharmacological activation of autophagy in Machado-Joseph diseaseFerreira, Ana Cristina Lopes Vasconcelos masterThesisopenAccess
10114-Dec-2020Phenotypic characterization of cellular and animal models of Machado-Joseph diseaseOliveira, Ana Daniela EstevesmasterThesisembargoedAccess
102Jan-2005Platelet hyperactivation in maintained growth hormone-deficient childhood patients after therapy withdrawal as a putative earlier marker of increased cardiovascular riskReis, Flávio ; Campos, Maria Vitor ; Bastos, Margarida ; Almeida, Luis ; Lourenço, Margarida ; Ferrer-Antunes, Carlos A. ; Palmeiro, Aida ; Santos-Dias, José D. ; Mesquita, José F. ; Carvalheiro, Manuela ; Teixeira, Frederico articleopenAccess
10312-Mar-2018Polymeric Micelles to improve Salinomycin delivery to cancer cells.Kreutzer, Bruna masterThesisopenAccess
10418-Jul-2019Processos Biotecnológicos Aplicados ao Transplante de ÓrgãosJacinto, Sara Henrique Silvestre NevesmasterThesisopenAccess
105Sep-2016Produção e purificação de vetores virais adeno-associados para terapia génicaAbrunheiro, Vasco António JesusotheropenAccess
10611-May-2011Proliferative hypothalamic neurospheres express NPY, AGRP, POMC, CART and Orexin-A and differentiate to functional neuronsSousa-Ferreira, Lígia ; Álvaro, Ana Rita ; Aveleira, Célia ; Santana, Magda ; Brandão, Inês ; Kügler, Sebastian ; Almeida, Luís Pereira de ; Cavadas, Cláudia articleopenAccess
1072005Relative bioavailability and bioquivalence of three different oral formulations of Eslicarbazepine AcetateNunes, Teresa ; Falcão, Amílcar ; Almeida, Luís ; Lima, Ricardo ; Tavares, Susana ; Neta, Carla ; Fontes-Ribeiro, Carlos ; Macedo, Tice ; Soares-da-Silva, Patricio articleopenAccess
10830-Jul-2020Relatório de Estágio e Monografia intitulada "Transposição de Escala da Produção de Vírus Adeno-Associados"Canoeiro, Nuno Rafael FernandesmasterThesisopenAccess
10930-Jul-2014Relatório de estágio em farmácia comunitáriaNunes, Frederico de BritomasterThesisopenAccess
11022-Sep-2020Relatórios de Estágio e Monografia intitulada "Edição de Bases: o futuro da edição de genes?Fernandes, Irina Marques da SilvamasterThesisopenAccess
11125-Sep-2017Relatórios de Estágio e Monografia intitulada "Exossomas e outras vesículas extracelulares como biomarcadores"Silva, Márcio Alexandre da Costa e masterThesisopenAccess
11218-Jul-2019Relatórios de Estágio e Monografia intitulada “Biotecnologia Aplicada à Doença de Parkinson: Estratégias de Terapia Génica”Ribeiro, André Filipe SantosmasterThesisopenAccess
11314-Sep-2017Relatórios de Estágio e Monografia intitulada “CRISPR/Cas9 na produção de modelos de doença do cérebro”.Ferreira, Joana Catarina Martins masterThesisopenAccess
11419-Sep-2017Relatórios de Estágio e Monografia intitulada “Exossomas – novos vetores para o transporte, entrega e tratamento de doenças do cérebro”Silva, Maria Margarida Carvalho Vale da masterThesisopenAccess
11510-Sep-2019Relatórios de Estágio e Monografia intitulada “Novos Mecanismos de Nitração in vivo: o efeito do nitrato da dieta na formação de ácido gordos nitrados com ação anti-inflamatória”Cadima, Cecília MonizmasterThesisopenAccess
11614-Sep-2020Relatórios de Estágio e Monografia Intitulada"Imunidade pré-existente a AAV: Estratégias para desenvolver vetores AAV com evasão imune aprimorada"Mano, Diogo Miguel Alves PratasmasterThesisopenAccess
117Jul-2015Reparação génica de iPSC através do sistema CRISPR/CAS9Lopes, Olga Maria da SilvaotheropenAccess
1182019Restoring brain cholesterol turnover improves autophagy and has therapeutic potential in mouse models of spinocerebellar ataxiaNóbrega, Clévio David Rodrigues ; Mendonça, Liliana Simões ; Marcelo, Adriana Isabel do Vale ; Lamazière, Antonin; Tomé, Sandra Marisa Oliveira ; Despres, Gaetan; Matos, Carlos A; Mechmet, Fatich; Langui, Dominique; den Dunnen, Wilfred; Almeida, Luís Pereira de ; Cartier, Nathalie; Alves, Sandro José Paiva Fernandes articleembargoedAccess
11921-Aug-2014RNA Interference Mitigates Motor and Neuropathological Deficits in a Cerebellar Mouse Model of Machado-Joseph DiseaseNóbrega, Clévio ; Nascimento-Ferreira, Isabel ; Onofre, Isabel ; Albuquerque, David ; Déglon, Nicole ; Almeida, Luís Pereira de articleopenAccess
12011-Apr-2013Role of Brain-Derived Neurotrophic Factor and Mitochondrial Function in Huntington's DiseaseSilva, Ana Cristina Rosa da doctoralThesisopenAccess
12121-Mar-2017Role of microRNA deregulation in the pathogenesis of Machado-Joseph diseaseVijayakumar, Udaya Geetha doctoralThesisembargoedAccess
122Mar-2016Safety profile of the intravenous administration of brain-targeted stable nucleic acid lipid particlesConceição, Mariana ; Mendonça, Liliana ; Nóbrega, Clévio; Gomes, Célia ; Costa, Pedro ; Hirai, Hirokazu; Moreira, João Nuno ; Lima, Maria C. Pedroso de ; Manjunath, N.; Almeida, Luís Pereira de articleopenAccess
12317-Dec-2020SARS-CoV-2 detection methods: where are we now?Ferreira, Victor Leonel VieiramasterThesisembargoedAccess
1242013Silencing mutant ataxin-3 rescues motor deficits and neuropathology in Machado-Joseph disease transgenic miceNóbrega, Clévio ; Nascimento-Ferreira, Isabel ; Onofre, Isabel ; Albuquerque, David ; Hirai, Hirokazu; Déglon, Nicole ; Almeida, Luís Pereira de articleopenAccess
12511-Sep-2020Simple and Fast SEC-Based Protocol to Isolate Human Plasma-Derived Extracellular Vesicles for Transcriptional ResearchGaspar, Laetitia da Silva ; Santana, Magda M. ; Henriques, Carina ; Pinto, Maria M. ; Ribeiro-Rodrigues, Teresa M. ; Girão, Henrique ; Nobre, Rui Jorge ; Almeida, Luís Pereira de articleopenAccess
1262007siRNA delivery by a transferrin-associated lipid-based vector: a non-viral strategy to mediate gene silencingCardoso, A. L. C. ; Simões, S. ; Almeida, L. P. de ; Pelisek, J. ; Culmsee, C. ; Wagner, E. ; Lima, M. C. Pedroso de articleopenAccess
127Jul-2015Síndrome de Down: caracterização e perspectivas futurasJorge, Maria Inês LourençootheropenAccess
128Apr-2023A standardised protocol for blood and cerebrospinal fluid collection and processing for biomarker research in ataxiaSantana, Magda M. ; Gaspar, Laetitia S. ; Pinto, Maria M. ; Silva, Patrick Joel da ; Adão, Diana ; Pereira, Dina ; Ribeiro, Joana Afonso; Cunha, Inês ; Huebener-Schmid, Jeannette; Raposo, Mafalda; Ferreira, Ana F.; Faber, Jennifer; Kuhs, Sandra; Garcia-Moreno, Hector; Reetz, Kathrin; Thieme, Andreas; Infante, Jon; van de Warrenburg, Bart P. C.; Giunti, Paola; Riess, Olaf; Schöls, Ludger; Lima, Manuela ; Klockgether, Thomas; Januário, Cristina ; Almeida, Luís Pereira de articleopenAccess
1298-Jun-2021Stress granules, RNA-binding proteins and polyglutamine diseases: too much aggregation?Marcelo, Adriana ; Koppenol, Rebekah; Almeida, Luís Pereira de ; Matos, Carlos A.; Nóbrega, Clévio articleopenAccess
13015-Jul-2008Striatal and nigral pathology in a lentiviral rat model of Machado-Joseph diseaseAlves, Sandro ; Régulier, Etienne ; Nascimento-Ferreira, Isabel ; Hassig, Raymonde ; Dufour, Noelle ; Koeppen, Arnulf ; Carvalho, Ana Luísa ; Simões, Sérgio ; Lima, Maria C. Pedroso de ; Brouillet, Emmanuel ; Gould, Veronica Colomer ; Déglon, Nicole ; Almeida, Luís Pereira de articleopenAccess
1311-Aug-2018Stroma-derived IL-6, G-CSF and Activin-A mediated dedifferentiation of lung carcinoma cells into cancer stem cellsRodrigues, Carlos F. D. ; Serrano, Eurico ; Patrício, Maria I.; Val, Mariana; Albuquerque, Patrícia; Fonseca, João ; Gomes, Célia M. F. ; Abrunhosa, Antero ; Paiva, Artur ; Carvalho, Lina ; Botelho, Maria F. ; Almeida, Luís ; Carreira, Isabel M. ; Alpoim, Maria Carmen articleopenAccess
1322019Successes and Hurdles in Stem Cells Application and Production for Brain TransplantationHenrique, Daniel ; Moreira, Ricardo ; Schwamborn, Jens; Almeida, Luís Pereira de ; Mendonça, Liliana articleopenAccess
133Aug-2008Surfactants as microbicides and contraceptive agents: a systematic in vitro studyVieira, Otília V. ; Hartmann, Diego O. ; Cardoso, Carla M. P. ; Oberdoerfer, Daniel ; Baptista, Marta ; Santos, Manuel A. S. ; Almeida, Luis ; Ramalho-Santos, João: articleopenAccess
1342013Terapia génica da insuficiência cardíaca: potencial clínico da sobrexpressão da SERCA2aOliveira, Diogo Fernando Gonçalves demasterThesisopenAccess
13517-Sep-2019Terapia Génica na Diabetes Mellitus tipo 1Branco, Marta Salvado Abreu CastelomasterThesisopenAccess
1362008Tf-lipoplexes for neuronal siRNA delivery: A promising system to mediate gene silencing in the CNSCardoso, A. L. C. ; Simões, S. ; Almeida, L. P. de ; Plesnila, N. ; Lima, M. C. Pedroso de ; Wagner, E. ; Culmsee, C. articleopenAccess
13725-Aug-2021The autophagy-enhancing drug carbamazepine improves neuropathology and motor impairment in mouse models of Machado-Joseph diseaseVasconcelos-Ferreira, Ana ; Carmo-Silva, Sara; Codêsso, José Miguel Antunes ; Silva, Patrick Joel da ; Martinez, Alberto Rolim Muro; França, Marcondes Cavalcante; Nóbrega, Clévio David Rodrigues ; Almeida, Luís Pereira de articleembargoedAccess
13831-Aug-2020The blood-brain barrier is disrupted in Machado-Joseph disease/spinocerebellar ataxia type 3: evidence from transgenic mice and human post-mortem samplesDuarte Lobo, Diana; Nobre, Rui J. ; Miranda, Catarina Sofia Oliveira ; Pereira, Dina ; Castelhano, João ; Sereno, José ; Koeppen, Arnulf ; Castelo-Branco, Miguel ; Almeida, Luís Pereira de articleopenAccess
13919-Oct-2021The Parkinson's-disease-associated mutation LRRK2-G2019S alters dopaminergic differentiation dynamics via NR2F1Walter, Jonas; Bolognin, Silvia; Poovathingal, Suresh K.; Magni, Stefano; Gérard, Deborah; Antony, Paul M. A.; Nickels, Sarah L.; Salamanca, Luis; Berger, Emanuel; Smits, Lisa M.; Grzyb, Kamil; Perfeito, Rita ; Hoel, Fredrik; Qing, Xiaobing; Ohnmacht, Jochen; Bertacchi, Michele; Jarazo, Javier; Ignac, Tomasz; Monzel, Anna S.; Gonzalez-Cano, Laura; Krüger, Rejko; Sauter, Thomas; Studer, Michèle; Almeida, Luís Pereira de ; Tronstad, Karl J.; Sinkkonen, Lasse; Skupin, Alexander; Schwamborn, Jens C.articleopenAccess
1409-Jan-2020The role of ageing in polyglutamine-induced neurodegeneration. A study in Machado-Joseph disease modelsPereira, Dina Maria da Silva RodriguesdoctoralThesisembargoedAccess
1411-Jun-2023The stress granule protein G3BP1 alleviates spinocerebellar ataxia-associated deficitsKoppenol, Rebekah; Conceição, André ; Afonso, Inês T.; Afonso-Reis, Ricardo; Costa, Rafael G.; Tomé, Sandra ; Teixeira, Diogo ; da Silva, Joana Pinto; Codêsso, José Miguel ; Brito, David V. C.; Mendonça, Liliana ; Marcelo, Adriana ; Almeida, Luís Pereira de ; Matos, Carlos A.; Nóbrega, Clévio articleopenAccess
1422013Transplante de células estaminais em doenças neurodegenerativasFerreira, Diana Marina TavaresotheropenAccess
1432015Trehalose alleviates neuropathological and motor behaviour deficits of a transgenic mouse model of Machado-Joseph diseasePaixão, Susana Manuel da Silva Letra LopesmasterThesisembargoedAccess
1449-Apr-2020Trehalose alleviates the phenotype of Machado-Joseph disease mouse modelsSantana, Magda M. ; Paixão, Susana ; Cunha-Santos, Janete; Silva, Teresa Pereira ; Trevino-Garcia, Allyson; Gaspar, Laetitia da Silva ; Nóbrega, Clévio ; Nobre, Rui J. ; Cavadas, Cláudia ; Greif, Hagar; Almeida, Luís Pereira de articleopenAccess
1452013Tumor-targeted Chlorotoxin-coupled Nanoparticles for Nucleic Acid Delivery to Glioblastoma Cells: A Promising System for Glioblastoma TreatmentCosta, Pedro M. ; Cardoso, Ana L. ; Mendonça, Liliana S. ; Serani, Angelo ; Custódia, Carlos ; Conceição, Mariana ; Simões, Sérgio ; Moreira, João N. ; Almeida, Luis Pereira de ; Lima, M. C. P. de articleopenAccess
1469-Jun-2017Unravelling the role of ataxin-2 in the hypothalamus: a new player in metabolismSilva, Sara Matias Carmo doctoralThesisembargoedAccess

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