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Title: Generation and characterization of a human iPS cell line from a patient-related control to study disease mechanisms associated with DAND5 p.R152H alteration
Authors: Pars, Selin
Cristo, Fernando
Inácio, José M.
Rosas, Graça
Carreira, Isabel Marques 
Melo, Joana Barbosa 
Mendes, Patrícia
Martins, Duarte Saraiva
Almeida, Luís Pereira de 
Maio, José
Anjos, Rui 
Belo, José A.
Issue Date: May-2018
Publisher: Elsevier
Project: FCT - (PTDC/BIM-MED/3363/2014) 
iNOVA4Health - UID/ Multi/04462/2013, a program financially supported by Fundação para a Ciência e Tecnologia/Ministério da Educação e Ciência, through national funds and co-funded by FEDER under the PT2020 Partnership Agreement is acknowledged 
Serial title, monograph or event: Stem Cell Research
Volume: 29
Abstract: A DAND5-control human iPSC line was generated from the urinary cells of a phenotypically normal donor. Exfoliated renal epithelial (RE) cells were collected and reprogrammed into iPSCs using Sendai virus reprogramming system. The pluripotency, in vitro differentiation potential, karyotype stability, and the transgene-free status of generated iPSC line were analyzed and confirmed. This cell line can be exploited as a control iPSC line to better understand the mechanisms involved in DAND5-associated cardiac disease.
ISSN: 18735061
DOI: 10.1016/j.scr.2018.04.015
Rights: openAccess
Appears in Collections:I&D CIBIT - Artigos em Revistas Internacionais
FMUC Medicina - Artigos em Revistas Internacionais
I&D CNC - Artigos em Revistas Internacionais

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