Loading... 2 0 20 0 false
 
Name
Peça, João
 
Variants
Peca, João
 
 
Email
jmpessa@gmail.com
 
Other emails
 
 
Ciência ID
 
Status
UC Researcher
Biography
João Peça is a neurobiologist with more than 15 years of research experience. Presently, he is Assistant Professor of Molecular and Cell Biology at the University of Coimbra and Group Leader of the Neuronal Circuits and Behavior Lab. João completed his Ph.D. at Duke University, where he created the first transgenic mice for channelrhodopsin-2 and pioneered the field of optogenetics. He performed postdoctoral research at MIT characterizing animal models for autism, where he uncovered a new role for cortico-striatal dysfunction in autism spectrum disorders. He has completed was supervisor or co-supervisor of 5 Ph.D. students' thesis and of 10+ M.Sc. students. Present interests of his group center on using advanced models to understand how genetic and environmental elements risk factors translate to neurodevelopmental and neuropsychiatric disorders. To achieve this, João uses a combination of molecular genetics, optogenetics and electrophysiological approaches using animal models and human brain organoids. To date his work has led to primary research papers in high-impact, peer-reviewed journals, including Nature, Nature Communications, Molecular Psychiatry, PNAS, and Neuron, and review work in Cell and Annual Reviews in Neuroscience. In 2019 he won "Pfizer Prize in Basic Research", the oldest and one of the most prestigious prizes in Portugal in the area of Biomedical Sciences.
Loading... 3 0 20 0 false

Publications

Results 1-18 of 18 (Search time: 0.134 seconds).

Issue DateTitleAuthor(s)TypeAccess
129-Mar-2019Abnormal mGluR-mediated synaptic plasticity and autism-like behaviours in Gprasp2 mutant miceEdfawy, Mohamed; Guedes, Joana R. ; Pereira, Marta I. ; Laranjo, Mariana ; Carvalho, Mário J. ; Gao, Xian; Ferreira, Pedro A. ; Caldeira, Gladys ; Franco, Lara O. ; Wang, Dongqing; Cardoso, Ana Luísa ; Feng, Guoping ; Carvalho, Ana Luisa ; Peça, João articleopenAccess
217-Jul-2023Author Correction: Efficient spatially targeted gene editing using a near-infrared activatable protein-conjugated nanoparticle for brain applicationsRebelo, Catarina ; Reis, Tiago ; Guedes, Joana ; Saraiva, Cláudia; Rodrigues, Artur Filipe ; Simões, Susana; Bernardino, Liliana ; Peça, João ; Pinho, Sónia L. C.; Ferreira, Lino articleopenAccess
3Sep-2017Blue light potentiates neurogenesis induced by retinoic acid-loaded responsive nanoparticlesSantos, Tiago ; Ferreira, Raquel ; Quartin, Emanuel ; Boto, Carlos ; Saraiva, Cláudia ; Bragança, José ; Peça, João ; Rodrigues, Cecília ; Ferreira, Lino ; Bernardino, Liliana articleopenAccess
42023Brain Gain – Discovering Neurosciences: A digital education outreach project for higher education studentsLaranjo, Mariana ; Amaral, Sara; Caetano, Carolina; Santos, Sílvio ; Campos, Rita ; Peça, João ; Seabra, Catarina M.articleopenAccess
522-Dec-2017Dissecting the role of GPRASP2 in autism spectrum disorder and intellectual disabilityHussien, Mohamed Edfawy SolimandoctoralThesisembargoedAccess
62016Dissection of hierarchy formation in mice: behavioral and molecular correlates of dominance.Sousa, Renato José Melo masterThesisembargoedAccess
716-Dec-2018Effects of a New Bioceramic Material on Human Apical Papilla CellsSequeira, Diana B. ; Seabra, Catarina M. ; Palma, Paulo J. ; Cardoso, Ana Luísa ; Peça, João ; Santos, João Miguel articleopenAccess
82022Efficient spatially targeted gene editing using a near-infrared activatable protein-conjugated nanoparticle for brain applicationsRebelo, Catarina ; Reis, Tiago ; Guedes, Joana ; Saraiva, Cláudia; Rodrigues, Artur Filipe ; Simões, Susana; Bernardino, Liliana ; Peça, João ; Pinho, Sónia L. C.; Ferreira, Lino articleopenAccess
92023Engineering optical tools for remotely controlled brain stimulation and regenerationRodrigues, Artur Filipe ; Rebelo, Catarina; Reis, Tiago ; Simões, Susana; Bernardino, Liliana; Peça, João ; Ferreira, Lino article; preprintembargoedAccess
1030-Oct-2014Expression and purification of Channelrhodopsin-2 in Pichia pastoris: generation of blue-shifted and redshifted optogenetic variantsMazza, Fabio masterThesisopenAccess
112015"Intelligent design of color-tuned ChR2 variants for optogenetics applications”Cruz, Bruno Filipe Oereira da masterThesisopenAccess
122021Ligand-independent activity of the ghrelin receptor modulates AMPA receptor trafficking and supports memory formationRibeiro, Luís F.; Catarino, Tatiana ; Carvalho, Mário; Cortes, Luísa ; Santos, Sandra D.; Opazo, Patricio O.; Ribeiro, Lyn Rosenbrier; Oliveiros, Bárbara ; Choquet, Daniel; Esteban, José A. ; Peça, João ; Carvalho, Ana Luísa articleopenAccess
1310-Oct-2018Long-term impact of early life stress on adult social behavior and prefrontal cortical circuitsFranco, Lara Oliveira doctoralThesisembargoedAccess
146-Mar-2020miRNA-31 Improves Cognition and Abolishes Amyloid-β Pathology by Targeting APP and BACE1 in an Animal Model of Alzheimer's DiseaseBarros-Viegas, Ana Teresa ; Carmona, Vitor ; Ferreiro, Elisabete ; Guedes, Joana ; Cardoso, Ana Maria S. ; Cunha, Pedro ; Almeida, Luís Pereira de ; Oliveira, Catarina Resende de ; Magalhães, João Pedro de ; Peça, João ; Cardoso, Ana Luísa articleopenAccess
152014Molecular mechanisms of the synaptic and cognitive effects of ghrelinCarvalho, Mário Jorge da Silva masterThesisopenAccess
169-Aug-2023A Novel Genetic Variant in MBD5 Associated with Severe Epilepsy and Intellectual Disability: Potential Implications on Neural Primary CiliaMartins, Mariana ; Oliveira, Ana Rafaela ; Martins, Solange ; Vieira, José Pedro; Perdigão, Pedro ; Fernandes, Ana Rita; Almeida, Luís Pereira de ; Palma, Paulo Jorge ; Sequeira, Diana Bela ; Santos, João Miguel Marques ; Duque, Frederico ; Oliveira, Guiomar ; Cardoso, Ana Luísa ; Peça, João ; Seabra, Catarina Morais articleopenAccess
172015Optogenetics and biotechnology : production and in vitro characterization of Ab-Initio designed channelrhodopsin-2 mutantsPereira, João Miguel CalmeiromasterThesisopenAccess
182022Therapeutic Approaches for Stroke: A Biomaterials PerspectiveRodrigues, Artur Filipe ; Rebelo, Catarina ; Reis, Tiago ; Sousa, João André; Pinho, Sónia L. C.; Sargento-Freitas, João; Peça, João ; Ferreira, Lino bookPartembargoedAccess