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Peça, João
Peca, João
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UC Researcher
João Peça is a neurobiologist with more than 15 years of research experience. Presently, he is Assistant Professor of Molecular and Cell Biology at the University of Coimbra and Group Leader of the Neuronal Circuits and Behavior Lab. João completed his Ph.D. at Duke University, where he created the first transgenic mice for channelrhodopsin-2 and pioneered the field of optogenetics. He performed postdoctoral research at MIT characterizing animal models for autism, where he uncovered a new role for cortico-striatal dysfunction in autism spectrum disorders. He has completed was supervisor or co-supervisor of 5 Ph.D. students' thesis and of 10+ M.Sc. students. Present interests of his group center on using advanced models to understand how genetic and environmental elements risk factors translate to neurodevelopmental and neuropsychiatric disorders. To achieve this, João uses a combination of molecular genetics, optogenetics and electrophysiological approaches using animal models and human brain organoids. To date his work has led to primary research papers in high-impact, peer-reviewed journals, including Nature, Nature Communications, Molecular Psychiatry, PNAS, and Neuron, and review work in Cell and Annual Reviews in Neuroscience. In 2019 he won "Pfizer Prize in Basic Research", the oldest and one of the most prestigious prizes in Portugal in the area of Biomedical Sciences.
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Results 1-16 of 16 (Search time: 0.034 seconds).

Issue DateTitleAuthor(s)TypeAccess
129-Mar-2019Abnormal mGluR-mediated synaptic plasticity and autism-like behaviours in Gprasp2 mutant miceEdfawy, Mohamed; Guedes, Joana R. ; Pereira, Marta I. ; Laranjo, Mariana ; Carvalho, Mário J. ; Gao, Xian; Ferreira, Pedro A. ; Caldeira, Gladys ; Franco, Lara O. ; Wang, Dongqing; Cardoso, Ana Luísa ; Feng, Guoping ; Carvalho, Ana Luisa ; Peça, João articleopenAccess
2Sep-2017Blue light potentiates neurogenesis induced by retinoic acid-loaded responsive nanoparticlesSantos, Tiago ; Ferreira, Raquel ; Quartin, Emanuel ; Boto, Carlos ; Saraiva, Cláudia ; Bragança, José ; Peça, João ; Rodrigues, Cecília ; Ferreira, Lino ; Bernardino, Liliana articleopenAccess
32023Brain Gain – Discovering Neurosciences: A digital education outreach project for higher education studentsLaranjo, Mariana ; Amaral, Sara; Caetano, Carolina; Santos, Sílvio ; Campos, Rita ; Peça, João ; Seabra, Catarina M.articleopenAccess
422-Dec-2017Dissecting the role of GPRASP2 in autism spectrum disorder and intellectual disabilityHussien, Mohamed Edfawy SolimandoctoralThesisembargoedAccess
52016Dissection of hierarchy formation in mice: behavioral and molecular correlates of dominance.Sousa, Renato José Melo masterThesisembargoedAccess
616-Dec-2018Effects of a New Bioceramic Material on Human Apical Papilla CellsSequeira, Diana B. ; Seabra, Catarina M. ; Palma, Paulo J. ; Cardoso, Ana Luísa ; Peça, João ; Santos, João Miguel articleopenAccess
72022Efficient spatially targeted gene editing using a near-infrared activatable protein-conjugated nanoparticle for brain applicationsRebelo, Catarina ; Reis, Tiago; Guedes, Joana ; Saraiva, Cláudia; Rodrigues, Artur Filipe ; Simões, Susana; Bernardino, Liliana ; Peça, João ; Pinho, Sónia L. C.; Ferreira, Lino articleopenAccess
82023Engineering optical tools for remotely controlled brain stimulation and regenerationRodrigues, Artur Filipe ; Rebelo, Catarina; Reis, Tiago; Simões, Susana; Bernardino, Liliana; Peça, João ; Ferreira, Lino article; preprintembargoedAccess
930-Oct-2014Expression and purification of Channelrhodopsin-2 in Pichia pastoris: generation of blue-shifted and redshifted optogenetic variantsMazza, Fabio masterThesisopenAccess
102015"Intelligent design of color-tuned ChR2 variants for optogenetics applications”Cruz, Bruno Filipe Oereira da masterThesisopenAccess
112021Ligand-independent activity of the ghrelin receptor modulates AMPA receptor trafficking and supports memory formationRibeiro, Luís F.; Catarino, Tatiana ; Carvalho, Mário; Cortes, Luísa ; Santos, Sandra D.; Opazo, Patricio O.; Ribeiro, Lyn Rosenbrier; Oliveiros, Bárbara ; Choquet, Daniel; Esteban, José A. ; Peça, João ; Carvalho, Ana Luísa articleopenAccess
1210-Oct-2018Long-term impact of early life stress on adult social behavior and prefrontal cortical circuitsFranco, Lara Oliveira doctoralThesisembargoedAccess
136-Mar-2020miRNA-31 Improves Cognition and Abolishes Amyloid-β Pathology by Targeting APP and BACE1 in an Animal Model of Alzheimer's DiseaseBarros-Viegas, Ana Teresa ; Carmona, Vitor ; Ferreiro, Elisabete ; Guedes, Joana ; Cardoso, Ana Maria S. ; Cunha, Pedro ; Almeida, Luís Pereira de ; Oliveira, Catarina Resende de ; Magalhães, João Pedro de ; Peça, João ; Cardoso, Ana Luísa articleopenAccess
142014Molecular mechanisms of the synaptic and cognitive effects of ghrelinCarvalho, Mário Jorge da Silva masterThesisopenAccess
152015Optogenetics and biotechnology : production and in vitro characterization of Ab-Initio designed channelrhodopsin-2 mutantsPereira, João Miguel CalmeiromasterThesisopenAccess
162022Therapeutic Approaches for Stroke: A Biomaterials PerspectiveRodrigues, Artur Filipe ; Rebelo, Catarina ; Reis, Tiago; Sousa, João André; Pinho, Sónia L. C.; Sargento-Freitas, João; Peça, João ; Ferreira, Lino bookPartembargoedAccess