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Credit Name
Santana, Isabel
 
Full Name
Santana, Maria Isabel Jacinto
 
Variants
Santana, Isabel
Santana, I.
 
Main Affiliation
 
 
 
Ciência ID
 
Scopus Author ID
 
Biography
Maria Isabel Jacinto Santana graduated in Medicine at the University of Coimbra in 1984, completed is PhD in Neurology (Alzheimer's Disease) in 1999 and is Full Professor of Neurology at the Faculty of Medicine of the University of Coimbra and co-coordinator of the Neurosciences and Mental Health Group since 2019. She is the director of the Neurology Department at the Centro Hospitalar e Universitário de Coimbra, being head of the Memory/Dementia Clinic and the Neuropsychological Unit and coordinator of the Coimbra Center at the European Alzheimers disease Consortium (EADC). Her main areas of expertise are neurodegenerative diseases in both clinical practise and translational investigation, including 20 years of experience in clinical trials and is a member of the National Ethics Committee for Clinical Investigation (CEIC) since 2017. As an integrated Member of the Center for Neuroscience and Cell Biology (CNC-UC) and head of the clinical/translational research group "Biomarkers in Neuropsychiatric Disorders: from Molecules to Diagnosis and Intervention" of the Center for Innovative Biomedicine and Biotechnology. She participates and/or has participated as Principal investigator in 13 project(s) and as Researcher in 26 project(s) with competitive financial support, received 26 awards and/or honors, is author/co-author of over 250 papers (6492 citations/h factor: 41), 31 books/section(s) of books and of more than 500 oral presentations in national and/or international scientific meetings. She has supervised/co-supervised 10 PhD thesis and 51 MSc dissertations.
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Status
UC Researcher
 

Publications

Results 1-64 of 64 (Search time: 0.001 seconds).

Issue DateTitleAuthor(s)TypeAccess
12008Adaptive visual memory reorganization in right medial temporal lobe epilepsyFigueiredo, Patrícia ; Santana, Isabel ; Teixeira, João ; Cunha, Catarina ; Machado, Egídeo ; Sales, Francisco ; Almeida, Eduarda ; Castelo-Branco, Miguel articleclosedAccess
210-Dec-2020Alterações Emocionais na Doença de Pequenos Vasos Cerebrais Esporádica e CADASIL: Revisão da literatura e estudo exploratórioSantos, Irina Sofia Reis GomesmasterThesisopenAccess
3Sep-2012APOE e transformação hemorrágica após administração de alteplase em doentes com acidente vascular cerebral isquémico agudoPedrosa, Isabel Sofia de Sousa masterThesisopenAccess
42006Association of HFE common mutations with Parkinson's disease, Alzheimer's disease and mild cognitive impairment in a Portuguese cohortGuerreiro, Rita J. ; Brás, José M. ; Santana, Isabel ; Januário, Cristina ; Santiago, Beatriz ; Morgadinho, Ana S. ; Ribeiro, Maria H. ; Hardy, John ; Singleton, Andrew ; Oliveira, Catarina articleopenAccess
53-Apr-2017Behavioral Symptoms in the Variants of Primary Progressive AphasiaMartins, Marta Oliveira masterThesisembargoedAccess
617-Jul-2014Características clínicas de doentes e portadores da expansão hexanucleotídica no gene C9ORF72Pires, José Guilherme Neri Miranda masterThesisopenAccess
72016Clinical validation of Alzheimer's disease assessment scale - cognitive sub-scale (ADAS-cog) - for the portuguese populationNogueira, Joana masterThesisopenAccess
828-Oct-2019Contributos para o estudo do Funcionamento Cognitivo e Emocional na Doença de Pequenos Vasos CerebraisAntónio, Inês Guedes Santos PatríciomasterThesisopenAccess
9Mar-2013Correlação entre localização e atividade epileptogénica : comparação entre epilepsias focais por tumores benignos e displasias corticais focaisBrás, Ana Catarina Branquinho masterThesisopenAccess
102011Defeito cognitivo ligeiro e doença de Alzheimer : conversão ou progressão?Carmo, João Filipe Guia Alves do masterThesisopenAccess
112010Defeito cognitivo ligeiro e psicopatologiaGonçalves, José Alves Grilo masterThesisopenAccess
122015Defeito cognitivo ligeiro:análise comparativa dos resultados nos testes de recordação selectiva livre e guiada (TRSLG), memória lógica (ML, WMS-III) e memória visuo-espacial (TBMV-VR)Bernardino, Sandra Isabel Teixeira masterThesisopenAccess
1330-Oct-2013Desempenho cognitivo não credível no declínio cognitivo ligeiro: estudos com o Test of Memory Malingering (TOMM) e o Rey-15Item Memory Test (Rey15-IMT)Jesus, Sara Adriana Silva de masterThesisopenAccess
14Feb-2012Determinação do estado redox do líquido céfalo-raquídeo na doença de AlzheimerSardo, Ana Isabel Franganito masterThesisopenAccess
152011Dieta mediterrânica e doença de AlzheimerPereira, Carolina Duarte masterThesisopenAccess
16Mar-2012Displasia cortical focal e epilepsia : comparação de EEG interictal e ictal com a localização da lesãoPatrocínio, João Pedro Silva Lima masterThesisopenAccess
171999A doença de Alois Alzheimer.Santana, Maria Isabel Jacinto doctoralThesisembargoedAccess
182016Domain-specific functional organization: neurocognitive characterization of a case of hemi-prosopometamorphopsiaFreixo, Andreia masterThesisopenAccess
1923-Oct-2017A Double Dissociation between Acting on and Knowing How to Act on ToolsValério, Daniela Filipa Codinha masterThesisclosedAccess
20Aug-2022Dual PET-fMRI reveals a link between neuroinflammation, amyloid binding and compensatory task-related brain activity in Alzheimer’s diseaseCanário, Nádia; Jorge, Lília; Martins, Ricardo ; Santana, Isabel ; Castelo Branco, Miguel articleopenAccess
2128-Nov-2018Early Transcranial Color-Coded Sonography as a predictor of Hemorrhagic Transformation after ThrombectomyCosta, André Jorge AssunçãomasterThesisembargoedAccess
222011Envelhecimento e défice cognitivo : estudos de adaptação, validação e normalização do Montreal Cognitive Assessment (MoCA)Freitas, Sandra doctoralThesisopenAccess
23Mar-2010Epidemiologia da demência em PortugalFarinha, Filipa Margarida Cardoso masterThesisopenAccess
242017Escala de Avaliação da Doença de Alzheimer – Subescala cognitiva (ADAS-Cog): Dados normativo para a população portuguesaNogueira, Joana ; Freitas, Sandra ; Duro, Diana ; Tábuas-Pereira, Miguel ; Guerreiro, Manuela ; Almeida, Jorge ; Santana, Isabel articleopenAccess
25Mar-2012Estudo da personalidade e de sintomas psicopatológicos na epilepsia de lobo temporal por esclerose mesialAndrade, Mariana Lacerda Moreira de Noronha e masterThesisopenAccess
262012Estudo de validação da versão portuguesa da Escala de Avaliação da Incapacidade Funcional na Demência (Disability Assessment for Dementia - DAD)Galhardo, Joana Rita Leonardo masterThesisopenAccess
272010Estudo de validação do Teste de Recordação Selectiva de Buschke – Buschke Selective Reminding TestAfonso, Ana Cristina de Sousa Faria workingPaperopenAccess
28Jan-2016Estudos de adaptação e aplicação de uma Escala de Gravidade da Afasia de causa vascularSilva, Miguel Neves Correia da masterThesisopenAccess
2931-Oct-2014Estudos de validação do Montreal Cognitive Assessment (MoCA) na esclerose múltipla: análise da equivalência das versões alternativas 2 e 3 e exploração do perfil de desempenho cognitivoSantiago, Joana Sofia Marques masterThesisopenAccess
3011-Aug-2020Face-Specific Perceptual Distortions Reveal A View- and Orientation-Independent Face TemplateAlmeida, Jorge Manuel Castelo Branco de Albuquerque ; Freixo, Andreia ; Tábuas-Pereira, Miguel ; Herald, Sarah B; Valério, Daniela Filipa Codinha ; Schu, Guilherme Garcia ; Duro, Diana ; Cunha, Gil ; Bukhari, Qasim; Duchaine, Brad; Santana, Isabel articleopenAccess
312004Frontotemporal dementia and mitochondrial DNA transitionsGrazina, Manuela ; Silva, Filipe ; Santana, Isabel ; Santiago, Beatriz ; Mendes, Cândida ; Simões, Marta; Oliveira, Miguel ; Cunha, Luís ; Oliveira, Catarina articleopenAccess
322006Genetic basis of Alzheimer's dementia: role of mtDNA mutationsGrazina, M. ; Pratas, J. ; Silva, F. ; Oliveira, S. ; Santana, I. ; Oliveira, C. articleopenAccess
332010Genetic screening of Alzheimer's disease genes in Iberian and African samples yields novel mutations in presenilins and APPGuerreiro, Rita João ; Baquero, Miquel ; Blesa, Rafael ; Boada, Mercè ; Brás, José Miguel ; Bullido, Maria. J. ; Calado, Ana ; Crook, Richard ; Ferreira, Carla; Frank, Ana ; Gómez-Isla, Teresa ; Hernández, Isabel ; Lleó, Alberto ; Machado, Álvaro ; Martínez- Lage, Pablo ; Masdeu, José ; Molina-Porcel, Laura ; Molinuevo, José L. ; Pastor, Pau ; Pérez-Tur, Jordi ; Relvas, Rute ; Oliveira, Catarina Resende ; Ribeiro, Maria Helena ; Rogaeva, Ekaterina ; Sá, Alfredo ; Samaranch, Lluís ; Sánchez-Valle, Raquel ; Santana, Isabel ; Tàrraga, Lluís ; Valdivieso, Fernando ; Singleton, Andrew ; Hardy, John ; Clarimón, Jordi articleopenAccess
343-Mar-2010Genetic Variability in CLU and Its Association with Alzheimer's DiseaseGuerreiro, Rita J. ; Beck, John ; Gibbs, J. Raphael ; Santana, Isabel ; Rossor, Martin N. ; Schott, Jonathan M. ; Nalls, Michael A. ; Ribeiro, Helena ; Santiago, Beatriz ; Fox, Nick C. ; Oliveira, Catarina ; Collinge, John ; Mead, Simon ; Singleton, Andrew ; Hardy, John articleopenAccess
35May-2011Glaucoma e doença de AlzheimerBrito, Sergio Filipe Seco da Silva masterThesisopenAccess
366-Mar-2019Impact of vitamin D in patients with epilepsySaraiva, Ana Margarida RajãomasterThesisembargoedAccess
3723-Jan-2021Investigating the Spatial Associations Between Amyloid-β Deposition, Grey Matter Volume, and Neuroinflammation in Alzheimer's DiseaseJorge, Lília; Martins, Ricardo Filipe Alves ; Canário, Nádia; Xavier, Carolina; Abrunhosa, Antero José Pena Afonso de ; Santana, Isabel ; Castelo-Branco, Miguel articleopenAccess
382021Knowing how to do it or doing it? A double dissociation between tool-gesture production and tool-gesture knowledgeValério, Daniela ; Santana, Isabel ; Sousa, Diana Aguiar de; Schu, Guilherme ; Leal, Gabriela; Pavão Martins, Isabel; Almeida, Jorge articleembargoedAccess
39Mar-2012A metamemória na progressão do défice cognitivo ligeiro para a doença de AlzheimerLopes, Lisete Cachinho masterThesisopenAccess
402004Mitochondria dysfunction of Alzheimer's disease cybrids enhances Aβ toxicityCardoso, Sandra M. ; Santana, Isabel ; Swerdlow, Russell H. ; Oliveira, Catarina R. articleopenAccess
412012Mitochondrial DNA involvement in frontotemporal lobar degeneration : analysis of sequence variants in MTND genesFernandes, Ana Sofia Cleto masterThesisopenAccess
42May-2013Mitochondrial DNA variants in complex V coding genes contributing to frontotemporal lobar degerationAbrantes, João Paulo Fernandes masterThesisopenAccess
432018Montreal Cognitive Assessment (MoCA) as a screening test for cognitive dysfunction in Multiple SclerosisFreitas, Sandra ; Batista, Sónia ; Afonso, Ana, C. ; Simões, Mário Rodrigues ; Sousa, Lívia de ; Cunha, Luís ; Santana, Isabel articleopenAccess
4417-Jul-2014Montreal Cognitive Assessment (MoCA): estudo de validação no défice cognitivo ligeiro vascularFerreira, Paulo Ricardo Alves masterThesisopenAccess
452013Montreal Cognitive Assessment (MoCA): Validation study for Mild Cognitive Impairment and Alzheimer´s DiseaseFreitas, Sandra ; Simões, Mário Rodrigues ; Alves, Lara ; Santana, Isabel articleopenAccess
4622-Dec-2017Neural correlates of theory of mind impairment in multiple sclerosisBaptista, Sónia Raquel Marques doctoralThesisembargoedAccess (2 years)
4713-Dec-2018Obesity as a risk factor for Alzheimer's disease: the role of adiponectinLetra, Liliana Rita Velindro doctoralThesisopenAccess
48Mar-2010ParassóniasGarcia, Ana Rita de Meira masterThesisopenAccess
492013Premorbid IQ influence on screening tests' scores in healthy patients and patients with cognitive impairmentAlves, Lara ; Simões, Mário Rodrigues ; Martins, Cristina ; Freitas, Sandra ; Santana, Isabel articleopenAccess
5030-May-2019Presurgical Evaluation of Memory Function in Epilepsy PatientsGonçalves, Carolina Barreto RodriguesmasterThesisembargoedAccess
51Mar-2012Processamento emocional :|binfluência de variáveis demográficasAbreu, Ana Carolina Canteiro masterThesisopenAccess
5231-Oct-2014Processamento emocional no defeito cognitivo ligeiroAntunes, Bárbara Ruivo masterThesisopenAccess
532014Psychometric properties of the Montreal Cognitive Assessment (MoCA): An analysis using the Rasch modelFreitas, Sandra ; Gerardo, Prieto ; Simões, Mário Rodrigues ; Santana, Isabel articleopenAccess
5419-Feb-2015Regulação genética do receptor 5-HT2A na Demência FrontotemporalLuís, Daniela Filipa Ribeiro doctoralThesisembargoedAccess
552015Scaling cognitive domains of the Montreal Cognitive Assessment (MoCA): An analysis using the Partial Credit ModelFreitas, Sandra ; Prieto, Gerardo ; Simões, Mário Rodrigues ; Santana, Isabel articleopenAccess
562013TeLPI Performance in subjects with Mild Cognitive Impairment and Alzheimer`s Disease: A validation studyAlves, Lara ; Simões, Mário Rodrigues ; Martins, Cristina ; Freitas, Sandra ; Santana, Isabel articleopenAccess
577-Apr-2021The Clock Drawing Test in the detection of cognitive impairment: Validation studies for the Portuguese populationDuro, Diana Filipa Dias doctoralThesisembargoedAccess
582015The relevance of sociodemographic and health variables on MMSE normative dataFreitas, Sandra ; Simões, Mário Rodrigues ; Alves, Lara ; Santana, Isabel articleopenAccess
592020The Retinal Inner Plexiform Synaptic Layer Mirrors Grey Matter Thickness of Primary Visual Cortex with Increased Amyloid β Load in Early Alzheimer's DiseaseJorge, Lília; Canário, Nádia; Martins, Ricardo ; Santiago, Beatriz ; Santana, Isabel ; Quental, Hugo; Ambrósio, Francisco ; Bernardes, Rui ; Castelo-Branco, Miguel articleopenAccess
602021The Revised Self-Monitoring Scale detects early impairment of social cognition in genetic frontotemporal dementia within the GENFI cohortFranklin, Hannah D; Russell, Lucy L; Peakman, Georgia; Greaves, Caroline V; Bocchetta, Martina; Nicholas, Jennifer; Poos, Jackie; Convery, Rhian S; Cash, David M; van Swieten, John; Jiskoot, Lize; Moreno, Fermin; Santana, Isabel ; Almeida, M. R.; Afonso, S.articleopenAccess
6120-Sep-2018Toulouse-Piéron Cancellation Test: Validation and normalization studies in cognitive declineNeves, Marisa Pedroso de Lima Marta masterThesisembargoedAccess
62Oct-2014Validation studies of the clock drawing test in mild cognitive impairmentCarneiro, Diogo Fernando Reis masterThesisopenAccess
6322-Mar-2016Verbal Memory and Visual Perception in early Alzheimer’s disease: Contribution of new diagnostic tools for new classification criteriaOliveira, Raquel Maria Baptista Lemos Guerra de doctoralThesisopenAccess
6430-Oct-2018Visuoconstructional impairment in Mild Cognitive Impairment: Diagnostic utility and predictive value in the progression to Alzheimer’s diseaseGerardo, Bianca Salguinho masterThesisopenAccess