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Issue DateTitleAuthor(s)TypeAccess
13-May-2021Inheritable testicular metabolic memory of high-fat diet causes transgenerational sperm defects in miceCrisóstomo, Luís; Jarak, Ivana ; Rato, Luís P; Raposo, João F; Batterham, Rachel L; Oliveira, Pedro F. ; Alves, Marco GarticleopenAccess
218-May-2021Neuromodulation and neuroprotective effects of chlorogenic acids in excitatory synapses of mouse hippocampal slicesFernandes, Mara Yone D.; Dobrachinski, Fernando; Silva, Henrique B. ; Lopes, João Pedro ; Gonçalves, Francisco Q. ; Soares, Felix A A; Porciúncula, Lisiane O. ; Andrade, Geanne M; Cunha, Rodrigo A. ; Tomé, Ângelo R. articleopenAccess
331-Aug-2020The blood-brain barrier is disrupted in Machado-Joseph disease/spinocerebellar ataxia type 3: evidence from transgenic mice and human post-mortem samplesDuarte Lobo, Diana; Nobre, Rui J. ; Miranda, Catarina Sofia Oliveira ; Pereira, Dina ; Castelhano, João ; Sereno, José ; Koeppen, Arnulf ; Castelo-Branco, Miguel ; Almeida, Luís Pereira de articleopenAccess
429-Jul-2019Sources of hepatic glycogen synthesis in mice fed with glucose or fructose as the sole dietary carbohydrateJarak, Ivana ; Barosa, Cristina ; Martins, Fátima O. ; Silva, Joao C. P.; Santos, Cristiano; Belew, Getachew Debas; Rito, João; Viegas, Ivan ; Teixeira, José; Oliveira, Paulo J. ; Jones, John Griffith articleembargoedAccess
5Apr-2020Estimating pentose phosphate pathway activity from the analysis of hepatic glycogen 13 C-isotopomers derived from [U-13 C]fructose and [U-13 C]glucoseBelew, Getachew D.; Di Nunzio, Giada; Tavares, Ludgero ; Silva, Joao G.; Torres, Alejandra N.; Jones, John Griffith articleembargoedAccess
614-Apr-2020Memory of Divisional History Directs the Continuous Process of Primitive Hematopoietic Lineage CommitmentBernitz, Jeffrey M; Rapp, Katrina; Daniel, Michael G.; Shcherbinin, Dmitrii; Yuan, Ye; Gomes, Andreia ; Waghray, Avinash; Brosh, Ran; Lachmann, Alexander; Ma'ayan, Avi; Papatsenko, Dmitri; Moore, Kateri A.articleopenAccess
72019Establishing a Link between Endothelial Cell Metabolism and Vascular Behaviour in a Type 1 Diabetes Mouse ModelSilva, Carolina; Sampaio-Pinto, Vasco; Andrade, Sara ; Rodrigues, Ilda; Costa, Raquel; Guerreiro, Susana; Carvalho, Eugenia ; Pinto-do-Ó, Perpétua; Nascimento, Diana S; Soares, RaquelarticleopenAccess
826-Apr-2019Chronic stress triggers divergent dendritic alterations in immature neurons of the adult hippocampus, depending on their ultimate terminal fieldsDioli, Chrysoula; Patrício, Patrícia; Sousa, Nuno; Kokras, Nikolaos; Dalla, Christina; Guerreiro, Sara ; Santos-Silva, Miguel A.; Rego, Ana Cristina ; Pinto, Luísa ; Ferreiro, Elisabete ; Sotiropoulos, IoannisarticleopenAccess
92020Adenosine A2A receptors format long-term depression and memory strategies in a mouse model of Angelman syndromeMoreira-de-Sá, Ana ; Gonçalves, Francisco Q. ; Lopes, João P. ; Silva, Henrique B. ; Tomé, Ângelo R. ; Cunha, Rodrigo A. ; Canas, Paula articleopenAccess
1023-Oct-2018Oncolysis with DTT-205 and DTT-304 generates immunological memory in cured animalsZhou, Heng; Mondragón, Laura; Xie, Wei; Mauseth, Brynjar; Leduc, Marion; Sauvat, Allan; Silva, Lígia C. Gomes da ; Forveille, Sabrina; Iribarren, Kristina; Souquere, Sylvie; Bezu, Lucillia; Liu, Peng; Zhao, Liwei; Zitvogel, Laurence; Sveinbjørnsson, Baldur; Eksteen, J Johannes; Rekdal, Øystein; Kepp, Oliver; Kroemer, GuidoarticleopenAccess
1129-Mar-2019Abnormal mGluR-mediated synaptic plasticity and autism-like behaviours in Gprasp2 mutant miceEdfawy, Mohamed; Guedes, Joana R. ; Pereira, Marta I. ; Laranjo, Mariana ; Carvalho, Mário J. ; Gao, Xian; Ferreira, Pedro A. ; Caldeira, Gladys ; Franco, Lara O. ; Wang, Dongqing; Cardoso, Ana Luísa ; Feng, Guoping ; Carvalho, Ana Luisa ; Peça, João articleopenAccess
122018Neuronal Adenosine A2A Receptors Are Critical Mediators of Neurodegeneration Triggered by ConvulsionsCanas, Paula M. ; Porciúncula, Lisiane O. ; Simões, Ana Patrícia ; Augusto, Elisabete de Oliveira ; Silva, Henrique B. ; Machado, Nuno J. ; Gonçalves, Nélio ; Alfaro, Tiago M. ; Gonçalves, Francisco Q. ; Araújo, Inês M. ; Real, Joana I. ; Coelho, Joana E. ; Andrade, Geanne M. ; Almeida, Ramiro D. ; Chen, Jiang-Fan ; Köfalvi, Attila ; Agostinho, Paula ; Cunha, Rodrigo A. articleopenAccess
1317-Nov-2020Distinct oligodendrocyte populations have spatial preference and different responses to spinal cord injuryFloriddia, Elisa M.; Lourenço, Tânia ; Zhang, Shupei; van Bruggen, David; Hilscher, Markus M.; Kukanja, Petra; Gonçalves Dos Santos, João P.; Altınkök, Müge; Yokota, Chika; Llorens-Bobadilla, Enric; Mulinyawe, Sara B; Grãos, Mário ; Sun, Lu O.; Frisén, Jonas; Nilsson, Mats; Castelo-Branco, GonçaloarticleopenAccess
1416-Apr-2020Glioblastoma hijacks microglial gene expression to support tumor growthMaas, Sybren L. N.; Abels, Erik R.; Van De Haar, Lieke L.; Zhang, Xuan; Morsett, Liza; Sil, Srinjoy; Guedes, Joana ; Sen, Pritha; Prabhakar, Shilpa; Hickman, Suzanne E.; Lai, Charles P.; Ting, David T.; Breakefield, Xandra O.; Broekman, Marike L. D.; El Khoury, JosepharticleopenAccess
1522-Mar-2021Synaptotagmin-7 places dense-core vesicles at the cell membrane to promote Munc13-2- and Ca2+-dependent primingTawfik, Bassam; Martins, Joana S; Houy, Sébastien; Imig, Cordelia; Pinheiro, Paulo S. ; Wojcik, Sonja M; Brose, Nils; Cooper, Benjamin H; Sørensen, Jakob BalslevarticleopenAccess
162018Can we induce spermatogenesis in the domestic cat using an in vitro tissue culture approach?Silva, Andreia F. ; Escada-Rebelo, Sara ; Amaral, Sandra ; Santos Tavares, Renata ; Schlatt, Stefan; Ramalho-Santos, João ; Mota, Paula C. articleopenAccess
1716-Jul-2018The exercise sex gap and the impact of the estrous cycle on exercise performance in miceAguiar, Aderbal S. ; Speck, Ana Elisa ; Amaral, Inês M. ; Canas, Paula M. ; Cunha, Rodrigo A. articleopenAccess
182-Oct-2017Crosstalk between glial and glioblastoma cells triggers the "go-or-grow" phenotype of tumor cellsOliveira, Ana Isabel; Anjo, Sandra I. ; Vieira de Castro, Joana; Serra, Sofia C.; Salgado, António J. ; Manadas, Bruno ; Costa, Bruno M.articleopenAccess
1915-Feb-2017Horizontal transfer of whole mitochondria restores tumorigenic potential in mitochondrial DNA-deficient cancer cellsDong, Lan-Feng; Kovarova, Jaromira ; Bajzikova, Martina ; Bezawork-Geleta, Ayenachew ; Svec, David ; Endaya, Berwini ; Sachaphibulkij, Karishma; Coelho, Ana R. ; Sebkova, Natasa; Ruzickova, Anna; Tan, An S; Kluckova, Katarina ; Judasova, Kristyna ; Zamecnikova, Katerina; Rychtarcikova, Zuzana; Gopalan, Vinod; Andera, Ladislav; Sobol, Margarita ; Yan, Bing; Pattnaik, Bijay; Bhatraju, Naveen; Truksa, Jaroslav ; Stopka, Pavel; Hozak, Pavel ; Lam, Alfred K.; Sedlacek, Radislav; Oliveira, Paulo J. ; Kubista, Mikael ; Agrawal, Anurag; Dvorakova-Hortova, Katerina ; Rohlena, Jakub ; Berridge, Michael V. ; Neuzil, Jiri articleopenAccess
202017Extracellular Electrophysiological Measurements of Cooperative Signals in Astrocytes PopulationsMestre, Ana L. G.; Inácio, Pedro M. C.; Elamine, Youssef; Asgarifar, Sanaz; Lourenço, Ana S.; Cristiano, Maria L. S.; Aguiar, Paulo; Medeiros, Maria C. R. ; Araújo, Inês M. ; Ventura, João André ; Gomes, Henrique L.articleopenAccess
2119-Jan-2017Glucocorticoid receptor signalling activates YAP in breast cancerSorrentino, Giovanni; Ruggeri, Naomi; Zannini, Alessandro; Ingallina, Eleonora; Bertolio, Rebecca; Marotta, Carolina; Neri, Carmelo; Cappuzzello, Elisa; Forcato, Mattia; Rosato, Antonio; Mano, Miguel ; Bicciato, Silvio; Del Sal, GianninoarticleopenAccess
22Oct-2017Transcription factor NRF2 controls the fate of neural stem cells in the subgranular zone of the hippocampusRobledinos-Antón, Natalia; Rojo, Ana I; Ferreiro, Elisabete ; Núñez, Ángel; Krause, Karl-Heinz; Jaquet, Vincent; Cuadrado, AntonioarticleopenAccess
2325-Aug-2017The Parkinson's disease-associated GPR37 receptor interacts with striatal adenosine A2A receptor controlling its cell surface expression and function in vivoMorató, Xavier; Luján, Rafael; López-Cano, Marc; Gandía, Jorge; Stagljar, Igor; Watanabe, Masahiko; Cunha, Rodrigo A. ; Fernández-Dueñas, Víctor; Ciruela, Francisco articleopenAccess
2419-Jul-2017Involvement of the p62/NRF2 signal transduction pathway on erythrophagocytosisSantarino, Inês; Viegas, Michelle ; Domingues, Neuza S. ; Ribeiro, Ana M.; Soares, Miguel P.; Vieira, Otília V.articleopenAccess
252016Long-Term Treatment with Low Doses of Methamphetamine Promotes Neuronal Differentiation and Strengthens Long-Term Potentiation of Glutamatergic Synapses onto Dentate Granule NeuronsBaptista, Sofia ; Lourenço, Joana; Milhazes, Nuno ; Borges, Fernanda; Silva, Ana Paula ; Bacci, AlbertoarticleopenAccess
2610-Jun-2016Oncostatin M promotes excitotoxicity by inhibiting glutamate uptake in astrocytes: implications in HIV-associated neurotoxicityMoidunny, Shamsudheen; Matos, Marco ; Wesseling, Evelyn; Banerjee, Santanu; Volsky, David J.; Cunha, Rodrigo A.; Agostinho, Paula ; Boddeke, Hendrikus W.; Roy, SabitaarticleopenAccess
2711-May-2016Caloric restriction blocks neuropathology and motor deficits in Machado-Joseph disease mouse models through SIRT1 pathwayCunha-Santos, Janete ; Duarte-Neves, Joana ; Carmona, Vitor ; Guarente, Leonard; Almeida, Luís Pereira de ; Cavadas, Cláudia articleopenAccess
2827-Sep-2016Blunted dynamics of adenosine A2A receptors is associated with increased susceptibility to Candida albicans infection in the elderlyRodrigues, Lisa ; Miranda, Isabel M.; Andrade, Geanne M. ; Mota, Marta ; Cortes, Luísa ; Rodrigues, Acácio G.; Cunha, Rodrigo A. ; Gonçalves, Teresa articleopenAccess
2921-Jul-2015Reduced α-MSH Underlies Hypothalamic ER-Stress-Induced Hepatic GluconeogenesisSchneeberger, Marc; Gómez-Valadés, Alicia G.; Altirriba, Jordi; Sebastián, David; Ramírez, Sara; Garcia, Ainhoa; Esteban, Yaiza; Drougard, Anne; Ferrés-Coy, Albert; Bortolozzi, Analía; Garcia-Roves, Pablo M.; Jones, John G. ; Manadas, Bruno ; Zorzano, Antonio; Gomis, Ramon; Claret, MarcarticleopenAccess
302015Nitric Oxide Regulates Neurogenesis in the Hippocampus following SeizuresCarreira, Bruno P. ; Santos, Daniela F; Santos, Ana I. ; Carvalho, Caetana M. ; Araújo, InêsarticleopenAccess
3126-Aug-2014Growth hormone pathways signaling for cell proliferation and survival in hippocampal neural precursors from postnatal miceDevesa, Pablo; Agasse, Fabienne ; Xapelli, Sara Alves ; Almengló, Cristina; Devesa, Jesús; Malva, João O. ; Arce, Víctor MarticleopenAccess
322017Anti-Inflammatory Strategy for M2 Microglial Polarization Using Retinoic Acid-Loaded NanoparticlesMachado-Pereira, Marta; Santos, Tiago ; Ferreira, Lino ; Bernardino, Liliana ; Ferreira, RaquelarticleopenAccess
3330-Jan-2013Activation of microglial cells triggers a release of brain-derived neurotrophic factor (BDNF) inducing their proliferation in an adenosine A2A receptor-dependent manner: A2A receptor blockade prevents BDNF release and proliferation of microgliaGomes, Catarina ; Ferreira, Raquel ; George, Jimmy ; Sanches, Rui; Rodrigues, Diana I. ; Gonçalves, Nélio ; Cunha, Rodrigo A. articleopenAccess
342013Differential contribution of the guanylyl cyclase-cyclic GMP-protein kinase G pathway to the proliferation of neural stem cells stimulated by nitric oxideCarreira, Bruno P. ; Morte, Maria Inês ; Lourenço, Ana Sofia ; Santos, Ana Isabel ; Inácio, Ângela ; Ambrósio, A. Francisco ; Carvalho, Caetana M. ; Araújo, Inês M. articleopenAccess
352013Silencing mutant ataxin-3 rescues motor deficits and neuropathology in Machado-Joseph disease transgenic miceNóbrega, Clévio ; Nascimento-Ferreira, Isabel ; Onofre, Isabel ; Albuquerque, David ; Hirai, Hirokazu; Déglon, Nicole ; Almeida, Luís Pereira de articleopenAccess
362013Brain-derived neurotrophic factor promotes vasculature-associated migration of neuronal precursors toward the ischemic striatumGrade, Sofia ; Weng, Yuan C.; Snapyan, Marina; Kriz, Jasna; Malva, João O. ; Saghatelyan, ArmenarticleopenAccess
372013Activation of type 1 cannabinoid receptor (CB1R) promotes neurogenesis in murine subventricular zone cell culturesXapelli, Sara Alves ; Agasse, Fabienne ; Sardà-Arroyo, Laura; Bernardino, Liliana ; Santos, Tiago ; Ribeiro, Filipa F.; Valero, Jorge ; Bragança, José ; Schitine, Clarissa; de Melo Reis, Ricardo A; Sebastião, Ana M. ; Malva, João O. articleopenAccess
388-May-2012Histamine modulates microglia functionFerreira, Raquel ; Santos, Tiago ; Gonçalves, Joana ; Baltazar, Graça ; Ferreira, Lino ; Agasse, Fabienne ; Bernardino, Liliana articleopenAccess
392012A new strategy based on SmRho protein loaded chitosan nanoparticles as a candidate oral vaccine against schistosomiasisOliveira, Carolina R.; Rezende, Cíntia M. F.; Silva, Marina R.; Pêgo, Ana Paula; Borges, Olga ; Goes, Alfredo M.articleopenAccess
402012Oral vaccination based on DNA-chitosan nanoparticles against Schistosoma mansoni infectionOliveira, Carolina R.; Rezende, Cíntia M. F.; Silva, Marina R.; Borges, Olga M. ; Pêgo, Ana P.; Goes, Alfredo M.articleopenAccess
4129-Nov-2010Functional and pathogenic differences of Th1 and Th17 cells in experimental autoimmune encephalomyelitisDomingues, Helena S. ; Mues, Marsilius; Lassmann, Hans; Wekerle, Hartmut; Krishnamoorthy, GurumoorthyarticleopenAccess
42Jul-2023Hypothalamic JNK1-hepatic fatty acid synthase axis mediates a metabolic rewiring that prevents hepatic steatosis in male mice treated with olanzapine via intraperitoneal: Additional effects of PTP1B inhibitionFerreira, Vitor; Folgueira, Cintia; García-Altares, María; Guillén, Maria; Ruíz-Rosario, Mónica; DiNunzio, Giada ; Garcia-Martinez, Irma; Alen, Rosa; Bookmeyer, Christoph; Jones, John G. ; Cigudosa, Juan C.; López-Larrubia, Pilar; Correig-Blanchar, Xavier; Davis, Roger J.; Sabio, Guadalupe; Rada, Patricia; Valverde, Angela M. articleopenAccess
439-Feb-2023Comparative Analysis of Retinal Organotypic Cultures and In Vivo Axotomized RetinasGonzález-Riquelme, María José; Lucas-Ruiz, Fernando; Galindo-Romero, Caridad; Boia, Raquel ; Ambrósio, António Francisco ; Vidal-Sanz, Manuel; Santiago, Ana Raquel ; Agudo-Barriuso, MartaarticleopenAccess
442023ECSIT is essential for RANKL-induced stimulation of mitochondria in osteoclasts and a target for the anti-osteoclastogenic effects of estrogensCarvalho, Adriana Marques ; Sardão, Vilma A. ; Kim, Ha-Neui; Almeida, Maria SarticleopenAccess
45Dec-2023The striatum drives the ergogenic effects of caffeinede Bem Alves, Ana Cristina; Speck, Ana Elisa ; Farias, Hémelin Resende; Martins, Leo Meira; Dos Santos, Naiara Souza; Pannata, Gabriela; Tavares, Ana Paula Gomes ; de Oliveira, Jade; Tomé, Ângelo R. ; Cunha, Rodrigo A. ; Aguiar, Aderbal S. articleopenAccess
469-Mar-2020Endophilin-A coordinates priming and fusion of neurosecretory vesicles via intersectinGowrisankaran, Sindhuja; Houy, Sébastien; Del Castillo, Johanna G Peña; Steubler, Vicky; Gelker, Monika; Kroll, Jana; Pinheiro, Paulo S. ; Schwitters, Dirk; Halbsgut, Nils; Pechstein, Arndt; van Weering, Jan R. T.; Maritzen, Tanja; Haucke, Volker; Raimundo, Nuno ; Sørensen, Jakob B.; Milosevic, Ira articleopenAccess
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