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Issue DateTitleAuthor(s)TypeAccess
12022Cerebellar morphometric and spectroscopic biomarkers for Machado-Joseph DiseaseMiranda, Catarina Oliveira ; Nobre, Rui Jorge ; Paiva, Vítor Hugo ; Duarte, João Valente ; Castelhano, João ; Petrella, Lorena Itati ; Sereno, José ; Santana, Magda ; Afonso, Sónia ; Januário, Cristina ; Castelo Branco, Miguel ; Almeida, Luís Pereira de articleopenAccess
21-Oct-2020SVEP1 as a Genetic Modifier of TEK-Related Primary Congenital GlaucomaYoung, Terri L.; Whisenhunt, Kristina N.; Jin, Jing; LaMartina, Sarah M.; Martin, Sean M.; Souma, Tomokazu; Limviphuvadh, Vachiranee; Suri, Fatemeh; Souzeau, Emmanuelle; Zhang, Xue; Dan, Yongwook; Anagnos, Evie; Carmona, Susana ; Jody, Nicole M.; Stangel, Nickie; Higuchi, Emily C.; Huang, Samuel J.; Siggs, Owen M.; Simões, Maria José; Lawson, Brendan M.; Martin, Jacob S.; Elahi, Elahe; Narooie-Nejad, Mehrnaz; Motlagh, Behzad Fallahi; Quaggin, Susan E.; Potter, Heather D.; Silva, Eduardo D. ; Craig, Jamie E.; Egas, Conceição ; Maroofian, Reza; Maurer-Stroh, Sebastian; Bradfield, Yasmin S.; Tompson, Stuart W.articleopenAccess
324-Dec-2014Differential regulation of the heat shock factor 1 and DAF-16 by neuronal nhl-1 in the nematode C. elegansVolovik, Yuli; Moll, Lorna; Marques, Filipa Carvalhal ; Maman, Moria; Bejerano-Sagie, Michal; Cohen, Ehud articleopenAccess
42011Visualização da rede linfática profunda usando radioliposomasBotelho, M. F. ; Lima, J. J. P. ; Dormehl, I. C. ; Baganha, M. Fontes; Gomes, C. M. ; Santos, A. C. ; Moreira, J. N. ; Kilian, E.articleopenAccess
52019ECM-enriched alginate hydrogels for bioartificial pancreas: an ideal niche to improve insulin secretion and diabetic glucose profileCrisóstomo, Joana ; Pereira, Ana M. ; Bidarra, Sílvia J.; Gonçalves, Ana C. ; Granja, Pedro L.; Coelho, Jorge Fj; Barrias, Cristina C; Seiça, Raquel articleopenAccess
6May-2017Hyperglycemia-induced degradation of HIF-1α contributes to impaired response of cardiomyocytes to hypoxiaRamalho, Ana Rita ; Toscano, Adriana ; Pereira, Paulo ; Girão, Henrique ; Gonçalves, Lino; Marques, Carla articleopenAccess
72020PINK1/PARKIN signalling in neurodegeneration and neuroinflammationQuinn, Peter M. J.; Moreira, Paula I. ; Ambrósio, António Francisco ; Alves, C. Henrique articleopenAccess
8Aug-2017Intestinal inflammatory and redox responses to the perioperative administration of teduglutide in ratsCosta, Beatriz Pinto ; Gonçalves, Ana Cristina ; Abrantes, Ana M. ; Matafome, Paulo N. ; Seiça, Raquel ; Ribeiro, Ana Bela Sarmento ; Botelho, Maria Filomena ; Castro-Sousa, Francisco articleopenAccess
95-Oct-2017Treatment with A2A receptor antagonist KW6002 and caffeine intake regulate microglia reactivity and protect retina against transient ischemic damageBoia, Raquel ; Elvas, Filipe ; Madeira, Maria H. ; Aires, Inês D. ; Rodrigues-Neves, Ana C. ; Tralhão, Pedro ; Szabó, Eszter C; Baqi, Younis; Müller, Christa E. ; Tomé, Ângelo R. ; Cunha, Rodrigo A. ; Ambrósio, Francisco ; Santiago, Ana R. articleopenAccess
102017Elevated Glucose and Interleukin-1β Differentially Affect Retinal Microglial Cell ProliferationBaptista, Filipa I. ; Aveleira, Célia A. ; Castilho, Áurea F. ; Ambrósio, António F. articleopenAccess
112017Having a Coffee Break: The Impact of Caffeine Consumption on Microglia-Mediated Inflammation in Neurodegenerative DiseasesMadeira, Maria H. ; Boia, Raquel ; Ambrósio, António F. ; Santiago, Ana R. articleopenAccess
12Jun-2017DIMP53-1: a novel small-molecule dual inhibitor of p53-MDM2/X interactions with multifunctional p53-dependent anticancer propertiesSoares, Joana; Espadinha, Margarida; Raimundo, Liliana; Ramos, Helena; Gomes, Ana Sara; Gomes, Sara; Loureiro, Joana B.; Inga, Alberto; Reis, Flávio ; Gomes, Célia ; Santos, Maria M. M.; Saraiva, LucíliaarticleopenAccess
132017Testing the excitation/inhibition imbalance hypothesis in a mouse model of the autism spectrum disorder: in vivo neurospectroscopy and molecular evidence for regional phenotypesGonçalves, Joana ; Violante, Inês R. ; Sereno, José ; Leitão, Ricardo A. ; Cai, Ying; Abrunhosa, Antero ; Silva, Ana Paula ; Silva, Alcino J.; Castelo-Branco, Miguel articleopenAccess
1421-Jun-2017Glucose and Lipid Dysmetabolism in a Rat Model of Prediabetes Induced by a High-Sucrose DietBurgeiro, Ana ; Cerqueira, Manuela G. ; Varela-Rodríguez, Bárbara M; Nunes, Sara ; Neto, Paula; Pereira, Frederico C. ; Reis, Flávio ; Carvalho, Eugenia articleopenAccess
1513-Oct-2017Vitamin D and Age-Related Macular DegenerationLayana, Alfredo Garcia; Minnella, Angelo Maria; Garhöfer, Gerhard; Aslam, Tariq; Holz, Frank G; Leys, Anita; Silva, Rufino ; Delcourt, Cécile; Souied, Eric; Seddon, Johanna M.articleopenAccess
162017mTOR Signaling in Cardiometabolic Disease, Cancer, and Aging [Editorial]Das, Anindita; Reis, Flávio ; Maejima, Yasuhiro; Cai, Zhiyou; Ren, JunarticleopenAccess
1730-Oct-2017The Sulforaphane and pyridoxamine supplementation normalize endothelial dysfunction associated with type 2 diabetesPereira, Ana ; Fernandes, Rosa ; Crisóstomo, Joana ; Seiça, Raquel M. ; Sena, Cristina M. articleopenAccess
1810-May-2017Methylglyoxal-induced glycation changes adipose tissue vascular architecture, flow and expansion, leading to insulin resistanceRodrigues, Tiago ; Matafome, Paulo N. ; Sereno, José ; Almeida, José; Castelhano, João ; Gamas, Luís ; Neves, Christian ; Gonçalves, Sónia ; Carvalho, Catarina ; Arslanagic, Amina ; Wilcken, Elinor ; Fonseca, Rita ; Simões, Ilda; Conde, Silvia Vilares; Castelo-Branco, Miguel ; Seiça, Raquel articleopenAccess
1921-Oct-2016Natural killer cell-based adoptive immunotherapy eradicates and drives differentiation of chemoresistant bladder cancer stem-like cellsFerreira-Teixeira, Margarida ; Paiva-Oliveira, Daniela ; Parada, Belmiro ; Alves, Vera ; Sousa, Vítor ; Chijioke, Obinna; Münz, Christian; Reis, Flávio ; Rodrigues-Santos, Paulo ; Gomes, Célia articleopenAccess
202016Long-Term Treatment with Low Doses of Methamphetamine Promotes Neuronal Differentiation and Strengthens Long-Term Potentiation of Glutamatergic Synapses onto Dentate Granule NeuronsBaptista, Sofia ; Lourenço, Joana; Milhazes, Nuno ; Borges, Fernanda; Silva, Ana Paula ; Bacci, AlbertoarticleopenAccess
212016Safety profile of solid lipid nanoparticles loaded with rosmarinic acid for oral use: in vitro and animal approachesMadureira, Ana Raquel; Nunes, Sara ; Campos, Débora A; Fernandes, João C. ; Marques, Cláudia; Zuzarte, Mónica ; Gullón, Beatriz; Rodríguez-Alcalá, Luís M.; Calhau, Conceição ; Sarmento, Bruno ; Gomes, Ana Maria; Pintado, Maria Manuela ; Reis, Flávio articleopenAccess
2225-Dec-2015Resistance to Recombinant Human Erythropoietin Therapy in a Rat Model of Chronic Kidney Disease Associated AnemiaGarrido, Patrícia ; Ribeiro, Sandra; Fernandes, João ; Vala, Helena; Rocha-Pereira, Petronila ; Bronze-da-Rocha, Elsa; Belo, Luís; Costa, Elísio; Santos-Silva, Alice; Reis, Flávio articleopenAccess
232016The Adenosinergic System in Diabetic RetinopathyVindeirinho, J. ; Santiago, A. R. ; Cavadas, C; Ambrósio, António F. ; Santos, P. F. articleopenAccess
2426-Jan-2016Reactivation of wild-type and mutant p53 by tryptophanolderived oxazoloisoindolinone SLMP53-1, a novel anticancer small-moleculeSoares, Joana; Raimundo, Liliana; Pereira, Nuno A. L.; Monteiro, Ângelo; Gomes, Sara; Bessa, Cláudia; Pereira, Clara; Queiroz, Glória; Bisio, Alessandra; Fernandes, João ; Gomes, Célia ; Reis, Flávio ; Gonçalves, Jorge; Inga, Alberto; Santos, Maria M. M.; Saraiva, LucíliaarticleopenAccess
258-Jun-2016Caffeine administration prevents retinal neuroinflammation and loss of retinal ganglion cells in an animal model of glaucomaMadeira, Maria H. ; Ortin-Martinez, Arturo; Nadal-Nícolas, Francisco; Ambrósio, António F. ; Vidal-Sanz, Manuel; Agudo-Barriuso, Marta; Santiago, Ana Raquel articleopenAccess
2611-Oct-2016Impact of splenic artery ligation after major hepatectomy on liver function, regeneration and viabilityCarrapita, Jorge; Abrantes, Ana Margarida ; Campelos, Sofia; Gonçalves, Ana Cristina; Cardoso, Dulce; Ribeiro, Ana Bela Sarmento ; Rocha, Clara ; Santos, Jorge Nunes; Botelho, Maria Filomena ; Tralhão, José Guilherme ; Farges, Olivier; Barbosa, Jorge MacielarticleopenAccess
272015Activation of Neuropeptide Y Receptors Modulates Retinal Ganglion Cell Physiology and Exerts Neuroprotective Actions In VitroMartins, João ; Elvas, Filipe ; Brudzewsky, Dan; Martins, Tânia ; Kolomiets, Bogdan; Tralhão, Pedro ; Gøtzsche, Casper R.; Cavadas, Cláudia ; Castelo-Branco, Miguel ; Woldbye, David P. D. ; Picaud, Serge; Santiago, Ana R. articleopenAccess
282015Probing insulin bioactivity in oral nanoparticles produced by ultrasonication-assisted emulsification/internal gelationLopes, Marlene A. ; Abrahim-Vieira, Bárbara; Oliveira, Claudia; Fonte, Pedro; Souza, Alessandra M. T.; Lira, Tammy; Sequeira, Joana A. D. ; Rodrigues, Carlos R.; Cabral, Lúcio M.; Sarmento, Bruno ; Seiça, Raquel ; Veiga, Francisco ; Ribeiro, António J. articleopenAccess
292015Irisin and Myonectin Regulation in the Insulin Resistant Muscle: Implications to Adipose Tissue: Muscle CrosstalkGamas, Luís ; Matafome, Paulo N. ; Seiça, Raquel articleopenAccess
3010-Jun-2015Adenosine A2AR blockade prevents neuroinflammation-induced death of retinal ganglion cells caused by elevated pressureMadeira, Maria H. ; Elvas, Filipe ; Boia, Raquel ; Gonçalves, Francisco Q. ; Cunha, Rodrigo A. ; Ambrósio, A. Francisco ; Santiago, Ana Raquel articleopenAccess
312015Iron-hepcidin dysmetabolism, anemia and renal hypoxia, inflammation and fibrosis in the remnant kidney rat modelGarrido, Patrícia ; Ribeiro, Sandra; Fernandes, João C. ; Vala, Helena; Bronze-da-Rocha, Elsa; Rocha-Pereira, Petronila ; Belo, Luís; Costa, Elísio; Santos-Silva, Alice; Reis, Flávio articleopenAccess
322015Nosewitness identification: effects of negative emotionAlho, Laura ; Soares, Sandra C. ; Ferreira, Jacqueline H. T. ; Rocha, Marta; Silva, Carlos F. ; Olsson, Mats J.articleopenAccess
332014Iron as the key modulator of hepcidin expression in erythroid antibody-mediated hypoplasiaFernandes, J. C. ; Garrido, P. ; Ribeiro, S.; Rocha-Pereira, P.; Bronze-da-Rocha, E.; Belo, L.; Costa, E.; Reis, F. ; Santos-Silva, A. articleopenAccess
3420-May-2014Transition from cyclosporine-induced renal dysfunction to nephrotoxicity in an in vivo rat modelSereno, José ; Rodrigues-Santos, Paulo ; Vala, Helena; Rocha-Pereira, Petronila ; Alves, Rui; Fernandes, João; Santos-Silva, Alice; Carvalho, Eugenia ; Teixeira, Frederico ; Reis, F. articleopenAccess
352014The Hidden Snake in the Grass: Superior Detection of Snakes in Challenging Attentional ConditionsSoares, Sandra C. ; Lindström, Björn; Esteves, Francisco ; Ohman, ArnearticleopenAccess
362014Deficient production of reactive oxygen species leads to severe chronic DSS-induced colitis in Ncf1/p47phox-mutant miceRodrigues-Sousa, Tiago ; Ladeirinha, Ana Filipa Ferreira ; Santiago, Ana Raquel ; Carvalheiro, Helena ; Raposo, Bruno; Alarcão, Ana ; Cabrita, António ; Holmdahl, Rikard; Carvalho, Lina ; Carneiro, M. Margarida Souto articleopenAccess
377-Mar-2013Early cardiac changes in a rat model of prediabetes: brain natriuretic peptide overexpression seems to be the best markerNunes, Sara ; Soares, Edna ; Fernandes, João ; Viana, Sofia D. ; Carvalho, Eugenia ; Pereira, Frederico C. ; Reis, Flávio articleopenAccess
3816-May-2013Neuropeptide Y receptors activation protects rat retinal neural cells against necrotic and apoptotic cell death induced by glutamateSantos-Carvalho, A. ; Elvas, F. ; Álvaro, A. R. ; Ambrósio, A. F. ; Cavadas, C. articleopenAccess
392013Differential contribution of the guanylyl cyclase-cyclic GMP-protein kinase G pathway to the proliferation of neural stem cells stimulated by nitric oxideCarreira, Bruno P. ; Morte, Maria Inês ; Lourenço, Ana Sofia ; Santos, Ana Isabel ; Inácio, Ângela ; Ambrósio, A. Francisco ; Carvalho, Caetana M. ; Araújo, Inês M. articleopenAccess
402013Diabetes alters KIF1A and KIF5B motor proteins in the hippocampusBaptista, Filipa I. ; Pinto, Maria J. ; Elvas, Filipe ; Almeida, Ramiro D. ; Ambrósio, A. Francisco articleopenAccess
414-Apr-2012Therapeutic implications of an enriched cancer stem-like cell population in a human osteosarcoma cell lineMartins-Neves, Sara R. ; Lopes, Áurio ; Carmo, Anália do ; Paiva, Artur A. ; Simões, Paulo C.; Abrunhosa, Antero ; Gomes, Célia M. F. articleopenAccess
422012Chemopreventive efficacy of Atorvastatin against nitrosamine-induced rat bladder cancer: antioxidant, anti-proliferative and anti-inflammatory propertiesParada, Belmiro ; Reis, Flávio ; Pinto, Ângela ; Sereno, José ; Cunha, Maria Xavier ; Neto, Paula; Rocha-Pereira, Petronila; Mota, Alfredo ; Figueiredo, Arnaldo ; Teixeira, Frederico articleopenAccess
436-Jul-2012Prevention of methamphetamine-induced microglial cell death by TNF-α and IL-6 through activation of the JAK-STAT pathwayCoelho-Santos, Vanessa ; Gonçalves, Joana ; Fontes-Ribeiro, Carlos A. ; Silva, Ana Paula articleopenAccess
448-May-2012Histamine modulates microglia functionFerreira, Raquel ; Santos, Tiago ; Gonçalves, Joana ; Baltazar, Graça ; Ferreira, Lino ; Agasse, Fabienne ; Bernardino, Liliana articleopenAccess
452012E-cadherin destabilization accounts for the pathogenicity of missense mutations in hereditary diffuse gastric cancerSimões-Correia, Joana ; Figueiredo, Joana; Lopes, Rui; Stricher, François; Oliveira, Carla; Serrano, Luís ; Seruca, Raquel articleopenAccess
462012Heme oxygenase-1 protects retinal endothelial cells against high glucose- and oxidative/nitrosative stress-induced toxicityCastilho, Áurea F. ; Aveleira, Célia A. ; Leal, Ermelindo C. ; Simões, Núria F. ; Fernandes, Carolina R. ; Meirinhos, Rita I. ; Baptista, Filipa I. ; Ambrósio, A. Francisco articleopenAccess
4728-Jan-2011Regular physical exercise training assists in preventing type 2 diabetes development: focus on its antioxidant and anti-inflammatory propertiesTeixeira-Lemos, Edite ; Nunes, Sara ; Teixeira, Frederico ; Reis, Flávio articleopenAccess
482011Diabetic nephropathy amelioration by a low-dose sitagliptin in an animal model of type 2 diabetes (Zucker diabetic fatty rat)Mega, Cristina ; Teixeira-Lemos, Edite ; Vala, Helena; Fernandes, Rosa ; Oliveira, Jorge; Mascarenhas-Melo, Filipa ; Teixeira, F. ; Reis, F. articleopenAccess
492011Differential effects of acute (extenuating) and chronic (training) exercise on inflammation and oxidative stress status in an animal model of type 2 diabetes mellitusTeixeira-Lemos, Edite ; Pinto, Rui; Oliveira, Jorge; Garrido, P. ; Sereno, José ; Mascarenhas-Melo, Filipa ; Pinheiro, João Páscoa ; Teixeira, F. ; Reis, Flávio articleopenAccess
502011Effects of 3,4-methylenedioxymethamphetamine administration on retinal physiology in the ratMartins, João ; Castelo-Branco, Miguel ; Batista, Ana ; Oliveiros, Bárbara ; Santiago, Ana Raquel ; Galvão, Joana ; Fernandes, Eduarda; Carvalho, Félix ; Cavadas, Cláudia ; Ambrósio, A. Francisco articleopenAccess
Results 1-50 of 53 (Search time: 0.176 seconds).