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de Sousa, Herminio C.
de Sousa, Herminio
de Sousa, H.C.
Sousa, H.C. de
Sousa, Hermínio José Cipriano de
Scopus Author ID
Researcher ID
Hermínio C. de Sousa (HC de Sousa) graduated in Chemical Engineering (5-years Lic. Chem Eng, 1992) from the New University of Lisbon, Portugal. He completed his PhD in 1997, in Chemistry - Physical Chemistry, also at the New University of Lisbon. At the same year he got a Teaching Assistant position at the Chemical Engineering Department, University of Coimbra, Portugal (DEQ-FCTUC), where he currently holds a Tenured Associate Professor position since 2019. He is a Senior Member of the Portuguese Association of Engineers (Portugal) and of the American Institute of Chemical Engineers (AIChE), USA. HC de Sousa has more than 20 years of academic experience in teaching theoretical, theoretical-practical, laboratorial and tutorial/supervision classes at the BSc, MSc and PhD levels. He was also a Visiting Professor/Researcher at the University of Massachusetts-Amherst, USA (2007, 2014), Federal University of Pará, Brazil (2009), UNICAMP, Brazil (2011, 2012), Federal University of Bahia, Brazil (2016, 2017, 2018, 2019), and National University of Colombia, Colombia (2013, 2014, 2017). HC de Sousa is the team leader of the Green and Sustainable Processes Laboratory (GSP), at the Chemical Process Engineering and Forest Products Research Centre of the Chemical Engineering Department of the University of Coimbra (CIEPQPF/DEQ-FCTUC). GSP research strategies and activities are mainly focused on the use of “greener”, sustainable, safer, biomimetic and environmentally-friendly innovative processes for the development of value-added products and materials/nanomaterials which are predominantly envisaged for pharmaceutical/drug delivery and biomedical/tissue engineering applications. However, food, agricultural, nutraceutical, cosmetic, antimicrobial, water treatment, oil & gas, electronics, and low VOC-emission materials/applications are/were also covered. Employed “greener” and sustainable approaches comprise the use of supercritical fluids (e.g., high-pressure, subcritical and supercritical carbon dioxide); of aqueous/ethanolic-based solvent systems; of natural-origin biopolymers and phytochemicals obtained from renewable resources (e.g., from vegetable raw materials and agro-industrial residues/wastes); of ionic liquids (namely of safer/biodegradable ionic liquids), and of “greener”, biomimetic and self-assembly-based synthesis/processing strategies. Several advantageous combinations of these five approaches were/are also implemented. Specific examples of application of the GSP research activities include the development of: nano/microparticles for drug delivery; implants, hydrogels and contact/intraocular lenses for ophthalmic drug delivery; medicated natural-origin wound dressings (namely for diabetic foot ulceration treatment); pre-formed and in-situ forming polymeric implants for prolonged drug/protein release; natural-origin adhesives and bioadhesives; bioactive natural products and their pharmaceutical/biomedical, food, nutraceutical, agricultural and cosmetic formulations/delivery systems; natural-origin flocculants for water treatment; plasticized low-VOC emission PVC/PU materials; and macro-, meso- and microporous silica-based biomaterials (e.g., biomimetic/bioactive biopolymer/silica composite/hybrid biomaterials - drug delivery/hard-tissue applications). More recent research topics include the development of: 1) multifunctional stimuli-responsive and electroactive biomaterials; 2) novel and more efficient materials and nanomaterials for oxygen/CO2/gas capture, storage, delivery and separation; 3) enhanced oil recovery and CO2/water-induced asphaltene precipitation in crude oil reservoirs; 4) improved and eco-friendly agricultural pesticide delivery, biomanagement and pest control (namely for insects/nematodes control); 5) supercritical CO2 as a sterilizing and biocidal agent.
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Results 1-72 of 72 (Search time: 0.002 seconds).

Issue DateTitleAuthor(s)TypeAccess
116-Dec-2020Adsorventes naturais e sintéticos como potenciais plataformas de libertação de bionematodicidas de base naftoquinonaFernandes, Jéssica Catarina MartinsmasterThesisembargoedAccess
228-Sep-2018Biomateriais bio-inspirados à base de sílica para aplicações biomédicas em tecidos durosMiraldo, André Manuel da Costa Patrão masterThesisopenAccess
3Feb-2014Chitosan-based dressings loaded with neurotensin—an efficient strategy to improve early diabetic wound healingMoura, Liane I. F. ; Dias, Ana M. A. ; Leal, Ermelindo C. ; Carvalho, Lina ; Sousa, Hermínio C. de ; Carvalho, Eugénia articleopenAccess
420-Sep-2013Chitosan-based polyionic liquidsGomes, Luís Filipe Ferreira masterThesisembargoedAccess
52022Chitosan-xanthan gum PEC-based aerogels: A chemically stable PEC in scCO2Tomé, Luciana I. N. ; Reis, Marco S. ; Sousa, Hermínio C. de ; Braga, Mara E. M. articleembargoedAccess
6Nov-2014Control of the properties of porous chitosan-alginate membranes through the addition of different proportions of Pluronic F68Bueno, Cecilia Zorzi ; Dias, Ana Maria Antunes ; Sousa, Hermínio José Cipriano de ; Braga, Mara Elga Medeiros ; Moraes, Angela Maria articleopenAccess
7Sep-2011Desenvolvimento de biomateriais compósitos à base de sílica utilizando técnicas "verdes" e biométricasAlves, Mariline Isabel de Castro masterThesisopenAccess
827-Sep-2018Desenvolvimento de formulações baseadas em atrativos/repelentes para o insecto-vetor do nemátode do pinheiroLeal, Vanessa Monteiro masterThesisembargoedAccess
915-Apr-2015Desenvolvimento de géis injectáveis para libertação controlada e localizada de fármacos em feridasBento, Ana Moniz Côrte-Real Granja masterThesisembargoedAccess
104-Sep-2019Desenvolvimento de nanocompósitos poliméricos reforçados com biopolimeros/polimeros com molhabilidade dispar do polimero-baseCordeiro, João Bernardo AranhamasterThesisembargoedAccess
1119-Jul-2018Desenvolvimento e caracterização de polielectrólitos multi-responsivosRosa, Maria João Brás e masterThesisembargoedAccess
1224-Sep-2015Development and characterization of biopolyelectrolytes functionalized with ionic liquids for transdermal drug delivery applicationsBarroso, Inês Pires Moedas de Almeida masterThesisopenAccess
13Sep-2012Development and characterization of chitosan and N-carboxybutylchitosan materials doped with biocompatible ionic liquids for application as stimuli-responsive biopolymersCortez, Ana Alexandra Rebelo masterThesisopenAccess
145-Nov-2013Development of novel therapeutic approaches for wound healing in diabetesMoura, Liane doctoralThesisopenAccess
1525-Sep-2017Development of ocular implants using a supercritical fluid foaming/ mixing methodologyBizarro, Sara Cristina DuartemasterThesisopenAccess
1618-Nov-2013Dexamethasone-loaded poly(ε-caprolactone)/silica nanoparticles composites prepared by supercritical CO2 foaming/mixing and depositionMatos, M. B. C. de ; Piedade, A. P. ; Alvarez-Lorenzo, C. ; Concheiro, A. ; Braga, M. E. M. ; Sousa, H. C. de articleopenAccess
1726-Sep-2018Dispositivos biomédicos com capacidade melhorada de captura e libertação de oxigénioMarques, Gustavo Filipe Bastos Silva Pinho masterThesisembargoedAccess
1826-Feb-2002Double Critical Phenomena in (Water + Polyacrylamides) SolutionsRebelo, L. P. N. ; Visak, Z. P. ; Sousa, H. C. de ; Szydlowski, J. ; Azevedo, R. Gomes de ; Ramos, A. M. ; Najdanovic-Visak, V. ; Ponte, M. Nunes da ; Klein, J. articleopenAccess
192011Drug loading strategies and processing of polymer blends for intraocular controlled drug release applicationTavares, Mădălina Victoria Natu doctoralThesisopenAccess
20Sep-2012Drug-eluting silica-poly (α-esters) biocomposite materials prepared by green tecnologiesMatos, Maria Betânia Carreira de masterThesisopenAccess
21Sep-2010Effects of drug solubility, state and loading on controlled release in bicomponent electrospun fibersNatu, Mădălina V. ; Sousa, Hermínio C. de ; Gil, M. H. articleopenAccess
222014Effects of Two Phosphonium-Type Ionic Liquids on the Rheological and Thermomechanical Properties of Emulsion Poly(vinyl chloride)-Based Formulations Plasticized with DINP and CITROFOLMarceneiro, Sofia ; Hu, Qingyun ; Dias, Ana M. A. ; Lobo, Irene ; Dias, Isabel ; Pinho, Elizabete de ; Rasteiro, M. Graça ; Sousa, Hermínio C. de articleopenAccess
232-Dec-2020Electro-responsive ionic liquid-based hydrogels for biomedical applicationsRibeiro, Patrícia Maria BaptistamasterThesisembargoedAccess
242011Electrospun Drug-Eluting Fibers for Biomedical ApplicationsNatu, Mădălina V. ; Sousa, Hermínio C. de ; Gil, Maria H. bookPartopenAccess
252020Environmentally-safe scCO2 P. pinaster branches extracts: Composition and propertiesGaspar, Marisa C. ; Sousa, Hermínio C. de ; Seabra, Inês J. ; Braga, Mara E. M. articleembargoedAccess
2614-Sep-2010Estratégias verdes e biométricas para o desenvolvimento de materiais compósitos sílica / biopolímeros / biomoléculas para aplicações biomédicas e de Engenharia de tecidosChim, Rita Joana de Almeida BentomasterThesisopenAccess
2711-May-2006Experimental Determination and Correlation of Artemisinin's Solubility in Supercritical Carbon DioxideCoimbra, Patrícia ; Blanco, Miguel R. ; Silva, Hélio S. R. Costa ; Gil, Maria H. ; Sousa, Hermínio C. de articleopenAccess
282010Extraction of valuable compounds from agro-residues of elder (Sambus nigra), pine (Pinus pinaster) and tara (Caesalpinia spinosa)Seabra, Inês José Abrantes de Oliveira doctoralThesisopenAccess
2928-Aug-2008Fractioned High Pressure Extraction of Anthocyanins from Elderberry ( Sambucus nigra L.) PomaceSeabra, Inês J. ; Braga, Mara E. M. ; Batista, Maria T. P. ; Sousa, Hermínio C. de articleopenAccess
3027-Feb-2017Green Methods for the Preparation of Novel Bone Cements Incorporating Highly Porous PCL/SBA-15 Composite BiomaterialsGouveia, João André de Silveira Dias masterThesisopenAccess
312020Impact of the pinewood nematode on naturally-emitted volatiles and scCO2 extracts from Pinus pinaster branches: a comparison with P. pineaGaspar, M. C. ; Agostinho, B.; Fonseca, L.; Abrantes, I. ; Sousa, H. C. de ; Braga, M. E. M. articleembargoedAccess
3215-Feb-2014Impregnation of cinnamaldehyde into cassava starch biocomposite films using supercritical fluid technology for the development of food active packagingSouza, Ana Cristina de ; Dias, Ana M. A. ; Sousa, Hermínio C. ; Tadini, Carmen C. articleopenAccess
33Aug-2014Improving cell adhesion: development of a biosensor for cell behaviour monitoring by surface grafting of sulfonic groups onto a thermoplastic polyurethaneAlves, P ; Pinto, S. ; Ferreira, P. ; Kaiser, Jean-Pierre ; Bruinink, Arie ; Sousa, Hermínio C. de ; Gil, M. H. articleopenAccess
34Jul-2011In vitro and in vivo evaluation of an intraocular implant for glaucoma treatmentNatu, Mădălina V. ; Gaspar, Manuel N. ; Ribeiro, Carlos A. Fontes ; Cabrita, António M. ; Sousa, Hermínio C. de ; Gil, M. H. articleopenAccess
352013Influence of natamycin loading methods on the physical characteristics of alginate active filmsBierhalz, Andrea C.K. ; Silva, Mariana A. da ; Sousa, Hermínio C. de ; Braga, Mara E. M. ; Kieckbusch, Theo G. articleopenAccess
36Jan-2013Influence of polymer processing technique on long term degradation of poly(ε-caprolactone) constructsNatu, Mădălina V. ; Sousa, Hermínio C. de ; Gil, M. H. article; preprintopenAccess
3717-Feb-2021Ionic liquid based functionalized materials for the development of multi-responsive electroactive hydrogelsKanaan, Akel FerreiradoctoralThesisembargoedAccess
3823-Sep-2015Libertação controlada de fármaco em lentes de contactoMendes, Sonia Filipa Xavier masterThesisopenAccess
3912-Apr-2017Membranas de base PVA mais eficientes para a captura e separação de gasesSousa, Sylvia Fernandes masterThesisembargoedAccess
4026-Jul-2018Nanoparticles-in-thermosensitive enemas as novel rectal anti-HIV microbiocidesMelo, Mélanie Almeida masterThesisembargoedAccess
419-Mar-2018Nanosistemas mais eficientes para terapia fotodinâmicaBuga, Cláudia Sofia Pessa masterThesisembargoedAccess
42Jan-2014Neurotensin-loaded collagen dressings reduce inflammation and improve wound healing in diabetic miceMoura, Liane I. F. ; Dias, Ana M. A. ; Suesca, Edward ; Casadiegos, Sergio ; Leal, Ermelindo C. ; Fontanilla, Marta R. ; Carvalho, Lina ; Sousa, Hermínio C. de ; Carvalho, Eugénia articleopenAccess
4328-Sep-2018Novos Materiais para a oxigenação melhorada de culturas de células e de scaffolds para Engenharia de TecidosSilva, Mariana Hugo Borges Barreto masterThesisembargoedAccess
4412-Sep-2011On the creation of aquatic inspired adhesive products with polykeetonesSjoerd van, Kuijk masterThesisopenAccess
451-Feb-2015Osteogenic poly(ε-caprolactone)/poloxamine homogeneous blends prepared by supercritical foamingMatos, Maria B. C. de ; Puga, Ana M. ; Alvarez-Lorenzo, Carmen ; Concheiro, Angel ; Braga, Mara E. M. ; Sousa, Hermínio C. de articleopenAccess
462001Phase behavior of (polyacrylamides + water) solutions: concentration, pressure and isotope effectsAzevedo, R. Gomes de ; Rebelo, L. P. N. ; Ramos, A. M. ; Szydlowski, J. ; Sousa, H. C. de ; Klein, J. articleopenAccess
4729-Sep-2017Polieletrólitos à base de líquidos iónicos para separação de aminoácidosAntunes, Andreia Sofia Rodrigues masterThesisembargoedAccess
4818-Sep-2013Poly (e-caprolactone)/SBA-15 composite biomaterials plasticized with greener additivesRosa, Antonio Barbosa Soares masterThesisopenAccess
492011A poly(ε-caprolactone) device for sustained release of an anti-glaucoma drugNatu, Mădălina V. ; Gaspar, Manuel N. ; Ribeiro, Carlos A. Fontes ; Correia, Ilídio J. ; Silva, Daniela ; Sousa, Hermínio C. de ; Gil, M. H. articleclosedAccess
509-Nov-2019Porous poly(ε-caprolactone) implants: A novel strategy for efficient intraocular drug deliveryBoia, Raquel ; Dias, Paulo A. N.; Martins, Joana M.; Galindo-Romero, Caridad; Aires, Inês D. ; Vidal-Sanz, Manuel; Agudo-Barriuso, Marta; Sousa, Hermínio C. de ; Ambrósio, António Francisco ; Braga, Mara E. M. ; Santiago, Ana Raquel articleopenAccess
5111-Sep-2015Preparação de compósitos a base de polímeros e sílica mesoporosa para aplicação em engenharia de tecidos duros utilizando a técnica de foaming por tecnologia supercríticaChurro, Rui Miguel Minhós masterThesisopenAccess
527-Dec-2010Preparação e caracterização de sistemas de libertação controlada de fármacos com base em polímeros de origem naturalCoimbra, Patrícia Manuela Almeida doctoralThesisopenAccess
532008Preparation and characterization of flurbiprofen-loaded poly(3-hydroxybutyrate-co-3-hydroxyvalerate) microspheresCoimbra, Patrícia A. ; Sousa, Hermínio C. de ; Gil, Maria H. articleopenAccess
5420-Nov-2003Pressure, Isotope, and Water Co-solvent Effects in Liquid−Liquid Equilibria of (Ionic Liquid + Alcohol) SystemsNajdanovic-Visak, Vesna ; Esperança, José M. S. S. ; Rebelo, Luís P. N. ; Ponte, Manuel Nunes da ; Guedes, Henrique J. R. ; Seddon, Kenneth R. ; Sousa, Hermínio C. de ; Szydlowski, Jerzy articleopenAccess
5528-Sep-2018Produção de grafeno por exfoliação de grafite proveniente de elétrodos com recurso a ultrassonsReis, Pedro Miguel Costa Ribeiro dos masterThesisopenAccess
56Jul-2013Recent advances on the development of wound dressings for diabetic foot ulcer treatment--a reviewMoura, Liane I. F. ; Dias, Ana M. A. ; Carvalho, Eugénia ; Sousa, Hermínio C. de articleopenAccess
5726-Sep-2019Secagem supercrítica de aerogéis compostos por polímeros naturais para aplicações biomédicasAgostinho, Beatriz SousamasterThesisembargoedAccess
5824-Sep-2015Soft contact lenses with improved oxygen capacityPinho, Rui Miguel Abrantes masterThesisembargoedAccess
59Sep-2014A soft lithography method for patterning calcium phosphate ceramicsPereira, Daniel de Melo masterThesisembargoedAccess
6013-Jan-2005Solubility of Acetazolamide in Supercritical Carbon Dioxide in the Presence of Ethanol as a CosolventDuarte, Ana Rita C. ; Santiago, Susana ; Sousa, Hermínio C. de ; Duarte, Catarina M. M. articleopenAccess
612015Solubility of all-trans retinoic acid in supercritical carbon dioxideRosa, António B. S. ; Marceneiro, Sofia ; Braga, Mara E. M. ; Dias, Ana M. A. ; Sousa, Hermínio C. de articleopenAccess
6214-Aug-2008Solubility of Diflunisal in Supercritical Carbon DioxideCoimbra, Patrícia ; Fernandes, Daniel ; Gil, Maria H. ; Sousa, Hermínio C. de articleopenAccess
6313-May-2004Solubility of Flurbiprofen in Supercritical Carbon DioxideDuarte, Ana Rita C. ; Coimbra, Patrícia ; Sousa, Hermínio C. de ; Duarte, Catarina M. M. articleopenAccess
642008Solubility of Irgacure® 2959 photoinitiator in supercritical carbon dioxide: Experimental determination and correlationCoimbra, Patrícia ; Fernandes, Daniel ; Ferreira, Paula ; Gil, Maria H. ; Sousa, Hermínio C. de articleopenAccess
652006Sorption and diffusion of dense carbon dioxide in a biocompatible polymerDuarte, Ana Rita C. ; Martins, Carlos ; Coimbra, Patrícia ; Gil, Maria H. M. ; Sousa, Hermínio C. de ; Duarte, Catarina M. M. articleopenAccess
662007Supercritical fluid impregnation of a biocompatible polymer for ophthalmic drug deliveryDuarte, Ana Rita C. ; Simplicio, Ana Luísa ; Vega-González, Arlette ; Subra-Paternault, Pascale ; Coimbra, Patrícia ; Gil, M. H. ; Sousa, Hermínio C. de ; Duarte, Catarina M. M. articleopenAccess
672008Supercritical solvent impregnation of ophthalmic drugs on chitosan derivativesBraga, Mara E. M. ; Pato, Maria T. Vaz ; Silva, Hélio S. R. Costa ; Ferreira, Elisabeth I. ; Gil, Maria H. ; Duarte, Catarina M. M. ; Sousa, Hermínio C. de articleopenAccess
68Nov-2008Supercritical solvent impregnation of poly(ɛ-caprolactone)/poly(oxyethylene-b-oxypropylene-b-oxyethylene) and poly(ɛ-caprolactone)/poly(ethylene-vinyl acetate) blends for controlled release applicationsNatu, Mădălina V. ; Gil, M. H. ; Sousa, Hermínio C. de articleopenAccess
6915-Oct-2013Surface grafting of carboxylic groups onto thermoplastic polyurethanes to reduce cell adhesionAlves, P. ; Ferreira, P. ; Kaiser, Jean-Pierre ; Salk, Natalie ; Bruinink, Arie ; Sousa, Hermínio C. de ; Gil, M. H. articleopenAccess
7023-Sep-2016Synthesis and characterization of ionic liquid based polyampholyte hydrogelsValente, Bárbara Sofia dos Reis masterThesisopenAccess
7115-Sep-2021Using High-Pressure Technology to Develop Antioxidant-Rich Extracts from Bravo de Esmolfe Apple ResiduesBordalo, Mário; Seabra, Inês J. ; Silva, Andreia Bento; Terrasso, Ana Paula; Brito, Catarina ; Serra, Margarida; Bronze, Maria R.; Duarte, Catarina M. M. ; Braga, Mara E. M. ; de Sousa, Herminio C. ; Serra, Ana TeresaarticleopenAccess
722013Wound dressings loaded with an anti-inflammatory jucá (Libidibia ferrea) extract using supercritical carbon dioxide technologyDias, A.M.A. ; Rey-Rico, A. ; Oliveira, R.A. ; Marceneiro, S. ; Alvarez-Lorenzo, C. ; Concheiro, A. ; Júnior, R.N.C. ; Braga, M. E. M. ; Sousa, H.C. de articleopenAccess