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Title: Supercritical fluid impregnation of a biocompatible polymer for ophthalmic drug delivery
Authors: Duarte, Ana Rita C. 
Simplicio, Ana Luísa 
Vega-González, Arlette 
Subra-Paternault, Pascale 
Coimbra, Patrícia 
Gil, M. H. 
Sousa, Hermínio C. de 
Duarte, Catarina M. M. 
Keywords: Supercritical fluids; Impregnation; Biocompatible polymers; Ophthalmic drug delivery
Issue Date: 2007
Citation: The Journal of Supercritical Fluids. 42:3 (2007) 373-377
Abstract: Supercritical fluid impregnation was tested to prepare a new ophthalmic drug delivery device. Poly(methylmethacrylate-co-ethylhexylacrylate-co-ethyleneglycoldimethacrylate), P(MMA-EHA-EGDMA) has been proposed by Mariz [M. Mariz, Preparação de uma lente intra-ocular dotada de um sistema de libertação controlada de fármaco, Master Thesis, Universidade de Coimbra, 1999] as a promising matrix to be used for intraocular delivery of anti-inflammatory drugs used in eye surgery. This matrix was successfully impregnated with flurbiprofen, a non-steroidal anti-inflammatory agent.
Rights: openAccess
Appears in Collections:FCTUC Eng.Química - Artigos em Revistas Internacionais

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