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Credit Name
Santana, Isabel
 
Name
Santana, I.
 
Variants
Santana, Isabel
Santana, I.
 
 
 
Ciência ID
 
Scopus Author ID
 
Status
UC Researcher
Biography
Maria Isabel Jacinto Santana graduated in Medicine at the University of Coimbra in 1984, completed is PhD in Neurology (Alzheimer's Disease) in 1999 and is Full Professor of Neurology at the Faculty of Medicine of the University of Coimbra and co-coordinator of the Neurosciences and Mental Health Group since 2019. She is the director of the Neurology Department at the Centro Hospitalar e Universitário de Coimbra, being head of the Memory/Dementia Clinic and the Neuropsychological Unit and coordinator of the Coimbra Center at the European Alzheimers disease Consortium (EADC). Her main areas of expertise are neurodegenerative diseases in both clinical practise and translational investigation, including 20 years of experience in clinical trials and is a member of the National Ethics Committee for Clinical Investigation (CEIC) since 2017. As an integrated Member of the Center for Neuroscience and Cell Biology (CNC-UC) and head of the clinical/translational research group "Biomarkers in Neuropsychiatric Disorders: from Molecules to Diagnosis and Intervention" of the Center for Innovative Biomedicine and Biotechnology. She participates and/or has participated as Principal investigator in 13 project(s) and as Researcher in 26 project(s) with competitive financial support, received 26 awards and/or honors, is author/co-author of over 250 papers (6492 citations/h factor: 41), 31 books/section(s) of books and of more than 500 oral presentations in national and/or international scientific meetings. She has supervised/co-supervised 10 PhD thesis and 51 MSc dissertations.
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Publications

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Results 1-65 of 65 (Search time: 0.002 seconds).

Issue DateTitleAuthor(s)TypeAccess
120-Mar-2018Addition of the Aβ42/40 ratio to the cerebrospinal fluid biomarker profile increases the predictive value for underlying Alzheimer's disease dementia in mild cognitive impairmentBaldeiras, Inês ; Santana, Isabel ; Leitão, Maria João ; Gens, Helena; Pascoal, Rui; Tábuas-Pereira, Miguel ; Beato-Coelho, José; Duro, Diana ; Almeida, Maria do Rosário ; Oliveira, Catarina Resende de articleopenAccess
230-May-2018Aphasia Rapid Test: Estudos de Tradução, Adaptação e Validação para a População PortuguesaTábuas-Pereira, Miguel ; Freitas, Sandra ; Beato-Coelho, José; Ribeiro, Joana; Parra, Joana; Martins, Cristina ; Silva, Miguel; Matos, Maria Assunção; Nogueira, Ana Rita; Silva, Fernando; Sargento-Freitas, João ; Cordeiro, Gustavo ; Cunha, Luís ; Santana, Isabel articleopenAccess
32006Association of HFE common mutations with Parkinson's disease, Alzheimer's disease and mild cognitive impairment in a Portuguese cohortGuerreiro, Rita J. ; Brás, José M. ; Santana, Isabel ; Januário, Cristina ; Santiago, Beatriz ; Morgadinho, Ana S. ; Ribeiro, Maria H. ; Hardy, John ; Singleton, Andrew ; Oliveira, Catarina articleopenAccess
4Feb-2023Associations between cortical β-amyloid burden, fornix microstructure and cognitive processing of faces, places, bodies and other visual objects in early Alzheimer's diseaseBourbon-Teles, José ; Jorge, Lília ; Canário, Nádia ; Martins, Ricardo ; Santana, Isabel ; Castelo-Branco, Miguel articleopenAccess
5May-2023Cerebellar and subcortical atrophy contribute to psychiatric symptoms in frontotemporal dementiaBussy, Aurélie; Levy, Jake P.; Best, Tristin; Patel, Raihaan; Cupo, Lani; Van Langenhove, Tim; Nielsen, Jørgen E.; Pijnenburg, Yolande; Waldö, Maria Landqvist; Remes, Anne M.; Schroeter, Matthias L.; Santana, Isabel ; Pasquier, Florence; Otto, Markus; Danek, Adrian; Levin, Johannes; Le Ber, Isabelle; Vandenberghe, Rik; Synofzik, Matthis; Moreno, Fermin; de Mendonça, Alexandre; Sánchez-Valle, Raquel ; Laforce, Robert; Langheinrich, Tobias; Gerhard, Alexander; Graff, Caroline; Butler, Chris R.; Sorbi, Sandro; Jiskoot, Lize; Seelaar, Harro; van Swieten, John C.; Finger, Elizabeth; Tartaglia, Maria Carmela; Masellis, Mario; Tiraboschi, Pietro; Galimberti, Daniela; Borroni, Barbara; Rowe, James B.; Bocchetta, Martina; Rohrer, Jonathan D. ; Devenyi, Gabriel A.; Chakravarty, M. Mallar; Ducharme, SimonarticleopenAccess
630-Jan-2020Cerebrospinal fluid lipocalin 2 as a novel biomarker for the differential diagnosis of vascular dementiaLlorens, Franc; Hermann, Peter; Villar-Piqué, Anna; Diaz-Lucena, Daniela; Nägga, Katarina; Hansson, Oskar; Santana, Isabel ; Schmitz, Matthias; Schmidt, Christian; Varges, Daniela; Goebel, Stefan; Dumurgier, Julien; Zetterberg, Henrik; Blennow, Kaj; Paquet, Claire; Baldeiras, Inês ; Ferrer, Isidro; Zerr, IngaarticleopenAccess
723-Nov-2019Clinical validation of the Lumipulse G cerebrospinal fluid assays for routine diagnosis of Alzheimer's diseaseLeitão, Maria João ; Spínola, Anuschka da Silva ; Santana, Isabel ; Olmedo, Veronica; Nadal, Alicia; Le Bastard, Nathalie; Baldeiras, Inês articleopenAccess
82022Cognitive composites for genetic frontotemporal dementia: GENFI-CogPoos, Jackie M; Moore, Katrina M; Nicholas, Jennifer; Russell, Lucy L; Peakman, Georgia; Convery, Rhian S; Jiskoot, Lize C; van der Ende, Emma; van den Berg, Esther; Papma, Janne M; Seelaar, Harro; Pijnenburg, Yolande A L; Moreno, Fermin; Sánchez-Valle, Raquel ; Borroni, Barbara; Laforce, Robert; Masellis, Mario; Tartaglia, Carmela; Graff, Caroline; Galimberti, Daniela; Rowe, James B; Finger, Elizabeth; Synofzik, Matthis; Vandenberghe, Rik; de Mendonça, Alexandre; Tiraboschi, Pietro; Santana, Isabel ; Ducharme, Simon; Butler, Chris; Gerhard, Alexander; Levin, Johannes; Danek, Adrian; Otto, Markus; Le Ber, Isabel; Pasquier, Florence; van Swieten, John C; Rohrer, Jonathan D. articleopenAccess
92021Cognitive Trajectories Following Acute Infection in Older Patients With and Without Cognitive Impairment: An 1-Year Follow-Up StudySilva, Ana Rita ; Regueira, Patrícia; Cardoso, Ana Luísa ; Baldeiras, Inês ; Santana, Isabel ; Cerejeira, Joaquim articleopenAccess
102021Combined Structural MR and Diffusion Tensor Imaging Classify the Presence of Alzheimer's Disease With the Same Performance as MR Combined With Amyloid Positron Emission Tomography: A Data Integration ApproachAgostinho, Daniel ; Caramelo, Francisco ; Moreira, Ana Paula ; Santana, Isabel ; Abrunhosa, Antero ; Castelo Branco, Miguel articleopenAccess
11Nov-2018Congenital heart disease: New challengesSantana, Isabel articleopenAccess
122018Data driven diagnostic classification in Alzheimer's disease based on different reference regions for normalization of PiB-PET images and correlation with CSF concentrations of Aβ speciesOliveira, Francisco ; Leuzy, Antoine; Castelhano, J. ; Chiotis, Konstantinos; Hasselbalch, Steen Gregers; Rinne, Juha; Mendonça, Alexandre de ; Otto, Markus; Lleó, Alberto ; Santana, Isabel ; Johansson, Jarkko; Anderl-Straub, Sarah; Arnim, Christine; Beer, Ambros; Blesa, Rafael ; Fortea, Juan; Sanna-Kaisa, Herukka; Portelius, Erik; Pannee, Josef; Zetterberg, Henrik; Blennow, Kaj; Moreira, Ana P. ; Abrunhosa, Antero ; Nordberg, Agneta; Castelo-Branco, Miguel articleopenAccess
132022Data-driven staging of genetic frontotemporal dementia using multi-modal MRIMcCarthy, Jillian; Borroni, Barbara; Sánchez-Valle, Raquel ; Moreno, Fermin; Laforce, Robert; Graff, Caroline; Synofzik, Matthis; Galimberti, Daniela; Rowe, James B; Masellis, Mario; Tartaglia, Maria Carmela; Finger, Elizabeth; Vandenberghe, Rik; de Mendonça, Alexandre; Tagliavini, Fabrizio ; Santana, Isabel ; Butler, Chris; Gerhard, Alex; Danek, Adrian; Levin, Johannes; Otto, Markus; Frisoni, Giovanni; Ghidoni, Roberta; Sorbi, Sandro; Jiskoot, Lize C; Seelaar, Harro; van Swieten, John C; Rohrer, Jonathan D. ; Iturria-Medina, Yasser; Ducharme, SimonarticleopenAccess
142021Disease-related cortical thinning in presymptomatic granulin mutation carriersBorrego-Écija, Sergi; Sala-Llonch, Roser; van Swieten, John; Borroni, Barbara; Moreno, Fermín; Masellis, Mario; Tartaglia, Carmela; Graff, Caroline; Galimberti, Daniela; Laforce, Robert; Rowe, James B; Finger, Elizabeth; Vandenberghe, Rik; Tagliavini, Fabrizio ; de Mendonça, Alexandre; Santana, Isabel ; Synofzik, Matthis; Ducharme, Simon; Levin, Johannes; Danek, Adrian; Gerhard, Alex; Otto, Markus; Butler, Chris; Frisoni, Giovanni; Sorbi, Sandro; Heller, Carolin; Bocchetta, Martina; Cash, David M; Convery, Rhian S; Moore, Katrina M; Rohrer, Jonathan D. ; Sánchez-Valle, Raquel ; Castelo-Branco, Miguel ; Almeida, Maria do Rosário ; Afonso, Sónia ; Leitão, Maria João ; GENFI Genetic FTD InitiativearticleopenAccess
15Aug-2022Dual PET-fMRI reveals a link between neuroinflammation, amyloid binding and compensatory task-related brain activity in Alzheimer’s diseaseCanário, Nádia ; Jorge, Lília ; Martins, Ricardo ; Santana, Isabel ; Castelo Branco, Miguel articleopenAccess
162015Epidemiologia da Demência e da Doença de Alzheimer em Portugal: Estimativas da Prevalência e dos Encargos Financeiros com a MedicaçãoSantana, Isabel ; Farinha, Filipa ; Freitas, Sandra ; Rodrigues, Vítor ; Carvalho, ÁlvaroarticleopenAccess
175-Jan-2019Erlangen Score as a tool to predict progression from mild cognitive impairment to dementia in Alzheimer's diseaseBaldeiras, Inês ; Santana, Isabel ; Leitão, Maria João ; Vieira, Daniela ; Duro, Diana; Mroczko, Barbara; Kornhuber, Johannes; Lewczuk, PiotrarticleopenAccess
182017Escala de Avaliação da Doença de Alzheimer – Subescala cognitiva (ADAS-Cog): Dados normativo para a população portuguesaNogueira, Joana ; Freitas, Sandra ; Duro, Diana ; Tábuas-Pereira, Miguel ; Guerreiro, Manuela ; Almeida, Jorge ; Santana, Isabel articleopenAccess
1928-Nov-2019Evaluation of Human Cerebrospinal Fluid Malate Dehydrogenase 1 as a Marker in Genetic Prion Disease PatientsZerr, Inga; Villar-Piqué, Anna; Schmitz, Vanda Edit; Poleggi, Anna; Pocchiari, Maurizio; Sánchez-Valle, Raquel ; Calero, Miguel; Calero, Olga; Baldeiras, Inês ; Santana, Isabel ; Kovacs, Gabor G.; Llorens, Franc; Schmitz, MatthiasarticleopenAccess
2011-Aug-2020Face-Specific Perceptual Distortions Reveal A View- and Orientation-Independent Face TemplateAlmeida, Jorge ; Freixo, Andreia ; Tábuas-Pereira, Miguel ; Herald, Sarah B.; Valério, Daniela ; Schu, Guilherme ; Duro, Diana ; Cunha, Gil ; Bukhari, Qasim; Duchaine, Brad; Santana, Isabel articleopenAccess
212004Frontotemporal dementia and mitochondrial DNA transitionsGrazina, Manuela ; Silva, Filipe ; Santana, Isabel ; Santiago, Beatriz ; Mendes, Cândida ; Simões, Marta; Oliveira, Miguel ; Cunha, Luís ; Oliveira, Catarina articleopenAccess
222006Genetic basis of Alzheimer's dementia: role of mtDNA mutationsGrazina, M. ; Pratas, J. ; Silva, F. ; Oliveira, S. ; Santana, I. ; Oliveira, C. articleopenAccess
232023Genetic forms of primary progressive aphasia within the GENetic Frontotemporal dementia Initiative (GENFI) cohort: comparison with sporadic primary progressive aphasiaSamra, Kiran; MacDougall, Amy M.; Bouzigues, Arabella; Bocchetta, Martina; Cash, David M.; Greaves, Caroline V.; Convery, Rhian S.; Hardy, Chris; van Swieten, John C.; Seelaar, Harro; Jiskoot, Lize C.; Moreno, Fermin; Sánchez-Valle, Raquel ; Laforce, Robert; Graff, Caroline; Masellis, Mario; Tartaglia, Maria Carmela; Rowe, James B.; Borroni, Barbara; Finger, Elizabeth; Synofzik, Matthis; Galimberti, Daniela; Vandenberghe, Rik; de Mendonça, Alexandre; Butler, Chris R.; Gerhard, Alexander; Ducharme, Simon; Le Ber, Isabelle; Santana, Isabel ; Pasquier, Florence; Levin, Johannes; Otto, Markus; Sorbi, Sandro; Warren, Jason D.; Rohrer, Jonathan D. ; Russell, Lucy L.articleopenAccess
242010Genetic screening of Alzheimer's disease genes in Iberian and African samples yields novel mutations in presenilins and APPGuerreiro, Rita João ; Baquero, Miquel ; Blesa, Rafael ; Boada, Mercè ; Brás, José Miguel ; Bullido, Maria. J. ; Calado, Ana ; Crook, Richard ; Ferreira, Carla; Frank, Ana ; Gómez-Isla, Teresa ; Hernández, Isabel ; Lleó, Alberto ; Machado, Álvaro ; Martínez- Lage, Pablo ; Masdeu, José ; Molina-Porcel, Laura ; Molinuevo, José L. ; Pastor, Pau ; Pérez-Tur, Jordi ; Relvas, Rute ; Oliveira, Catarina Resende ; Ribeiro, Maria Helena ; Rogaeva, Ekaterina ; Sá, Alfredo ; Samaranch, Lluís ; Sánchez-Valle, Raquel ; Santana, Isabel ; Tàrraga, Lluís ; Valdivieso, Fernando ; Singleton, Andrew ; Hardy, John ; Clarimón, Jordi articleopenAccess
253-Mar-2010Genetic Variability in CLU and Its Association with Alzheimer's DiseaseGuerreiro, Rita J. ; Beck, John ; Gibbs, J. Raphael ; Santana, Isabel ; Rossor, Martin N. ; Schott, Jonathan M. ; Nalls, Michael A. ; Ribeiro, Helena ; Santiago, Beatriz ; Fox, Nick C. ; Oliveira, Catarina ; Collinge, John ; Mead, Simon ; Singleton, Andrew ; Hardy, John articleopenAccess
262023Hemispheric Patterns of Recruitment of Object Processing Regions in Early Alzheimer's Disease: A Study Along the Entire Ventral StreamCanário, Nádia ; Jorge, Lília P. ; Santana, Isabel J. ; Castelo-Branco, Miguel articleopenAccess
272021Impairment of episodic memory in genetic frontotemporal dementia: A GENFI studyPoos, Jackie M; Russell, Lucy L; Peakman, Georgia; Bocchetta, Martina; Greaves, Caroline V; Jiskoot, Lize C; van der Ende, Emma L; Seelaar, Harro; Papma, Janne M; van den Berg, Esther; Pijnenburg, Yolande A L; Borroni, Barbara; Sánchez-Valle, Raquel ; Moreno, Fermin; Laforce, Robert; Graff, Caroline; Synofzik, Matthias; Galimberti, Daniela; Rowe, James B; Masellis, Mario; Tartaglia, Carmela; Finger, Elizabeth; Vandenberghe, Rik; de Medonça, Alexandre; Tagliavini, Fabrizio ; Butler, Chris R; Santana, Isabel ; Ber, Isabelle Le; Gerhard, Alex; Ducharme, Simon; Levin, Johannes; Danek, Adrian; Otto, Markus; Sorbi, Sandro; Pasquier, Florence; van Swieten, John C; Rohrer, Jonathan D. articleopenAccess
2817-Nov-2020Increased C-X-C Motif Chemokine Ligand 12 Levels in Cerebrospinal Fluid as a Candidate Biomarker in Sporadic Amyotrophic Lateral SclerosisAndrés-Benito, Pol; Povedano, Mònica; Domínguez, Raúl; Marco, Carla; Colomina, Maria J.; López-Pérez, Óscar; Santana, Isabel ; Baldeiras, Inês ; Martínez-Yelámos, Sergio; Zerr, Inga; Llorens, Franc; Fernández-Irigoyen, Joaquín; Santamaría, Enrique; Ferrer, IsidroarticleopenAccess
2923-Jan-2021Investigating the Spatial Associations Between Amyloid-β Deposition, Grey Matter Volume, and Neuroinflammation in Alzheimer's DiseaseJorge, Lília ; Martins, Ricardo Filipe Alves ; Canário, Nádia ; Xavier, Carolina; Abrunhosa, Antero José Pena Afonso de ; Santana, Isabel ; Castelo-Branco, Miguel articleopenAccess
302021Knowing how to do it or doing it? A double dissociation between tool-gesture production and tool-gesture knowledgeValério, Daniela ; Santana, Isabel ; Sousa, Diana Aguiar de; Schu, Guilherme ; Leal, Gabriela; Pavão Martins, Isabel; Almeida, Jorge articleembargoedAccess
31Apr-2023Language impairment in the genetic forms of behavioural variant frontotemporal dementiaSamra, Kiran; MacDougall, Amy M.; Bouzigues, Arabella; Bocchetta, Martina; Cash, David M.; Greaves, Caroline V.; Convery, Rhian S.; van Swieten, John C.; Seelaar, Harro; Jiskoot, Lize; Moreno, Fermin; Sánchez-Valle, Raquel ; Laforce, Robert; Graff, Caroline; Masellis, Mario; Tartaglia, Maria Carmela; Rowe, James B.; Borroni, Barbara; Finger, Elizabeth; Synofzik, Matthis; Galimberti, Daniela; Vandenberghe, Rik; de Mendonça, Alexandre; Butler, Christopher R.; Gerhard, Alexander; Ducharme, Simon; Le Ber, Isabelle; Tiraboschi, Pietro; Santana, Isabel ; Pasquier, Florence; Levin, Johannes; Otto, Markus; Sorbi, Sandro; Rohrer, Jonathan D. ; Russell, Lucy L; Genetic FTD Initiative (GENFI)articleopenAccess
3225-Oct-2019Lower CSF Amyloid-Beta1-42 Predicts a Higher Mortality Rate in Frontotemporal DementiaVieira, Daniela ; Durães, João; Baldeiras, Inês; Santiago, Beatriz ; Duro, Diana; Lima, Marisa ; Leitão, Maria João ; Tábuas-Pereira, Miguel ; Santana, Isabel articleopenAccess
332016MicroRNA deregulation and chemotaxis and phagocytosis impairment in Alzheimer's diseaseGuedes, Joana R. ; Santana, Isabel ; Cunha, Catarina ; Duro, Diana ; Almeida, Maria R. ; Cardoso, Ana M. ; Lima, Maria C. Pedroso de ; Cardoso, Ana L. articleopenAccess
34Apr-2016Mini-mental state examination: Avaliação dos novos dados normativos no rastreio e diagnóstico do défice cognitivoSantana, Isabel ; Duro, Diana ; Lemos, Raquel; Costa, Vanessa ; Pereira, Miguel; Simões, Mário R. ; Freitas, Sandra articleopenAccess
352004Mitochondria dysfunction of Alzheimer's disease cybrids enhances Aβ toxicityCardoso, Sandra M. ; Santana, Isabel ; Swerdlow, Russell H. ; Oliveira, Catarina R. articleopenAccess
362018Montreal Cognitive Assessment (MoCA) as a screening test for cognitive dysfunction in Multiple SclerosisFreitas, Sandra ; Batista, Sónia ; Afonso, Ana, C. ; Simões, Mário Rodrigues ; Sousa, Lívia de ; Cunha, Luís ; Santana, Isabel articleopenAccess
372013Montreal Cognitive Assessment (MoCA): Validation study for Mild Cognitive Impairment and Alzheimer´s DiseaseFreitas, Sandra ; Simões, Mário Rodrigues ; Alves, Lara ; Santana, Isabel articleopenAccess
38Mar-2023Motor symptoms in genetic frontotemporal dementia: developing a new module for clinical rating scalesSamra, Kiran; MacDougall, Amy M.; Peakman, Georgia; Bouzigues, Arabella; Bocchetta, Martina; Cash, David M.; Greaves, Caroline V.; Convery, Rhian S.; van Swieten, John C.; Jiskoot, Lize; Seelaar, Harro; Moreno, Fermin; Sánchez-Valle, Raquel ; Laforce, Robert; Graff, Caroline; Masellis, Mario; Tartaglia, Carmela; Rowe, James B.; Borroni, Barbara; Finger, Elizabeth; Synofzik, Matthis; Galimberti, Daniela; Vandenberghe, Rik; de Mendonça, Alexandre; Butler, Chris R.; Gerhard, Alexander; Ducharme, Simon; Le Ber, Isabelle; Tiraboschi, Pietro; Santana, Isabel ; Pasquier, Florence; Levin, Johannes; Otto, Markus; Sorbi, Sandro; Rohrer, Jonathan D. ; Russell, Lucy L.articleopenAccess
395-Jan-2023Network structure and transcriptomic vulnerability shape atrophy in frontotemporal dementiaShafiei, Golia; Bazinet, Vincent; Dadar, Mahsa; Manera, Ana L.; Collins, D. Louis; Dagher, Alain; Borroni, Barbara; Sánchez-Valle, Raquel ; Moreno, Fermin; Laforce, Robert; Graff, Caroline; Synofzik, Matthis; Galimberti, Daniela; Rowe, James B.; Masellis, Mario; Tartaglia, Maria Carmela; Finger, Elizabeth; Vandenberghe, Rik; de Mendonça, Alexandre; Tagliavini, Fabrizio ; Santana, Isabel ; Butler, Chris; Gerhard, Alex; Danek, Adrian; Levin, Johannes; Otto, Markus; Sorbi, Sandro; Jiskoot, Lize C.; Seelaar, Harro; van Swieten, John C.; Rohrer, Jonathan D. ; Misic, Bratislav; Ducharme, SimonarticleopenAccess
40May-2023Neuropsychiatric symptoms in genetic frontotemporal dementia: developing a new module for Clinical Rating ScalesSamra, Kiran; Macdougall, Amy; Peakman, Georgia; Bouzigues, Arabella; Bocchetta, Martina; Cash, David M.; Greaves, Caroline V.; Convery, Rhian S.; van Swieten, John C.; Jiskoot, Lize C.; Seelaar, Harro; Moreno, Fermin; Sánchez-Valle, Raquel ; Laforce, Robert; Graff, Caroline; Masellis, Mario; Tartaglia, Maria Carmela; Rowe, James B.; Borroni, Barbara; Finger, Elizabeth; Synofzik, Matthis; Galimberti, Daniela; Vandenberghe, Rik; de Mendonca, Alexandre; Butler, Christopher R.; Gerhard, Alexander; Ducharme, Simon; Le Ber, Isabelle; Tiraboschi, Pietro; Santana, Isabel ; Pasquier, Florence; Levin, Johannes; Otto, Markus; Sorbi, Sandro; Rohrer, Jonathan D. ; Russell, Lucy L.articleopenAccess
41May-2021Neuropsychological features of progranulin-associated frontotemporal dementia: a nested case-control studyLima, Marisa ; Tábuas-Pereira, Miguel ; Duro, Diana ; Durães, João ; Vieira, Daniela ; Baldeiras, Inês ; Almeida, Maria do Rosário ; Santana, Isabel articleopenAccess
422022Plasma Lipocalin 2 in Alzheimer's disease: potential utility in the differential diagnosis and relationship with other biomarkersHermann, Peter; Villar-Piqué, Anna; Schmitz, Matthias; Schmidt, Christian; Varges, Daniela; Goebel, Stefan; Bunck, Timothy; Lindemann, Hanna; Bogner, Carla; Santana, Isabel ; Baldeiras, Inês; Riggert, Joachim; Zerr, Inga; Llorens, FrancarticleopenAccess
4310-Jun-2023Population Pharmacokinetic Analysis of Perampanel in Portuguese Patients Diagnosed with Refractory EpilepsySilva, Rui ; Colom, Helena; Bicker, Joana ; Almeida, Anabela ; Silva, Ana; Sales, Francisco ; Santana, Isabel ; Falcão, Amílcar ; Fortuna, Ana articleopenAccess
4419-Jul-2017Predicting progression of mild cognitive impairment to dementia using neuropsychological data: a supervised learning approach using time windowsPereira, Telma; Lemos, Luís; Cardoso, Sandra; Silva, Dina; Rodrigues, Ana ; Santana, Isabel ; Mendonça, Alexandre de; Guerreiro, Manuela ; Madeira, Sara C.articleopenAccess
452013Premorbid IQ influence on screening tests' scores in healthy patients and patients with cognitive impairmentAlves, Lara ; Simões, Mário Rodrigues ; Martins, Cristina ; Freitas, Sandra ; Santana, Isabel articleopenAccess
4615-Aug-2023Prodromal language impairment in genetic frontotemporal dementia within the GENFI cohortSamra, Kiran; MacDougall, Amy M.; Bouzigues, Arabella; Bocchetta, Martina; Cash, David M.; Greaves, Caroline V.; Convery, Rhian S.; van Swieten, John C.; Jiskoot, Lize; Seelaar, Harro; Moreno, Fermin; Sánchez-Valle, Raquel ; Laforce, Robert; Graff, Caroline; Masellis, Mario; Tartaglia, Maria Carmela; Rowe, James B.; Borroni, Barbara; Finger, Elizabeth; Synofzik, Matthis; Galimberti, Daniela; Vandenberghe, Rik; de Mendonça, Alexandre; Butler, Chris R.; Gerhard, Alex; Ducharme, Simon; Le Ber, Isabelle; Tiraboschi, Pietro; Santana, Isabel ; Pasquier, Florence; Levin, Johannes; Otto, Markus; Sorbi, Sandro; Rohrer, Jonathan D. ; Russell, Lucy L.; Duro, Diana ; Leitão, Maria João ; Almeida, Maria do Rosário ; Afonso, Sónia articleopenAccess
4725-Apr-2016Prognosis of Early-Onset vs. Late-Onset Mild Cognitive Impairment: Comparison of Conversion Rates and Its PredictorsTábuas-Pereira, Miguel ; Baldeiras, Inês ; Duro, Diana ; Santiago, Beatriz ; Ribeiro, Maria Helena ; Leitão, Maria João ; Oliveira, Catarina ; Santana, Isabel articleopenAccess
484-Jan-2021Progression of Behavioral Disturbances and Neuropsychiatric Symptoms in Patients With Genetic Frontotemporal DementiaBenussi, Alberto; Premi, Enrico; Gazzina, Stefano; Brattini, Chiara; Bonomi, Elisa; Alberici, Antonella; Jiskoot, Lize; van Swieten, John C; Sánchez-Valle, Raquel ; Moreno, Fermin; Laforce, Robert; Graff, Caroline; Synofzik, Matthis; Galimberti, Daniela; Masellis, Mario; Tartaglia, Carmela; Rowe, James B; Finger, Elizabeth; Vandenberghe, Rik; de Mendonça, Alexandre; Tagliavini, Fabrizio ; Santana, Isabel ; Ducharme, Simon; Butler, Chris R; Gerhard, Alexander; Levin, Johannes; Danek, Adrian; Otto, Markus; Frisoni, Giovanni; Ghidoni, Roberta; Sorbi, Sandro; Le Ber, Isabelle; Pasquier, Florence; Peakman, Georgia; Todd, Emily; Bocchetta, Martina; Rohrer, Jonathan D. ; Borroni, Barbara; Afonso, Sónia ; Leitão, Maria João ; et al.articleopenAccess
492014Psychometric properties of the Montreal Cognitive Assessment (MoCA): An analysis using the Rasch modelFreitas, Sandra ; Gerardo, Prieto ; Simões, Mário Rodrigues ; Santana, Isabel articleopenAccess
502023Reconsidering the role of blood-brain barrier in Alzheimer's disease: From delivery to targetSousa, João André; Bernardes, Catarina; Bernardo-Castro, Sara ; Lino, Miguel ; Albino, Inês ; Ferreira, Lino; Brás, José ; Guerreiro, Rita; Tábuas-Pereira, Miguel ; Baldeiras, Inês ; Santana, Isabel ; Sargento-Freitas, João articleopenAccess
51Aug-2023Reduction of class I histone deacetylases ameliorates ER-mitochondria cross-talk in Alzheimer's diseaseMarinho, Daniela ; Ferreira, Ildete L. ; Lorenzoni, Ricardo ; Cardoso, Sandra M. ; Santana, Isabel ; Rego, A. Cristina articleopenAccess
523-Apr-2023Resective Epilepsy Surgery and Respective Histopathological Diagnoses: A Retrospective Cohort StudyJesus-Ribeiro, Joana ; Rebelo, Olinda ; Bento, Conceição; Pereira, Cristina Maria Gonçalves ; Robalo, Conceição ; Rito, Manuel; Pereira, Ricardo; Costa, José Augusto; Melo, Joana Barbosa ; Freire, António ; Santana, Isabel ; Sales, Francisco articleopenAccess
532019Retinal texture biomarkers may help to discriminate between Alzheimer's, Parkinson's, and healthy controlsNunes, Ana ; Silva, Gilberto ; Duque, Cristina; Januário, Cristina ; Santana, Isabel ; Ambrósio, António ; Castelo-Branco, Miguel ; Bernardes, Rui articleopenAccess
542015Scaling cognitive domains of the Montreal Cognitive Assessment (MoCA): An analysis using the Partial Credit ModelFreitas, Sandra ; Prieto, Gerardo ; Simões, Mário Rodrigues ; Santana, Isabel articleopenAccess
552019Semi-quantification and grading of amyloid PET: A project of the European Alzheimer's Disease Consortium (EADC)Chincarini, A.; Peira, E.; Morbelli, S.; Pardini, M.; Bauckneht, M.; Arbizu, J.; Castelo-Branco, Miguel ; Büsing, K. A.; de Mendonça, A.; Didic, M.; Dottorini, M.; Engelborghs, S.; Ferrarese, C.; Frisoni, G. B.; Garibotto, V.; Guedj, E.; Hausner, L.; Hugon, J.; Verhaeghe, J.; Mecocci, P.; Musarra, M.; Queneau, M.; Riverol, M.; Santana, Isabel ; Guerra, U. P.; Nobili, F.articleopenAccess
562013TeLPI Performance in subjects with Mild Cognitive Impairment and Alzheimer`s Disease: A validation studyAlves, Lara ; Simões, Mário Rodrigues ; Martins, Cristina ; Freitas, Sandra ; Santana, Isabel articleopenAccess
57May-2023Temporal dynamics predict symptom onset and cognitive decline in familial frontotemporal dementiaWhiteside, David J.; Malpetti, Maura; Jones, P Simon; Ghosh, Boyd C. P.; Coyle-Gilchrist, Ian; van Swieten, John C.; Seelaar, Harro; Jiskoot, Lize; Borroni, Barbara; Sánchez-Valle, Raquel ; Moreno, Fermin; Laforce, Robert; Graff, Caroline; Synofzik, Matthis; Galimberti, Daniela; Masellis, Mario; Tartaglia, Maria Carmela; Finger, Elizabeth; Vandenberghe, Rik; de Mendonça, Alexandre; Tagliavini, Fabrizio ; Butler, Chris R.; Santana, Isabel ; Ber, Isabelle Le; Gerhard, Alexander; Ducharme, Simon; Levin, Johannes; Danek, Adrian; Otto, Markus; Sorbi, Sandro; Pasquier, Florence; Bouzigues, Arabella; Russell, Lucy L.; Rohrer, Jonathan D. ; Rowe, James B.; Rittman, TimothyarticleopenAccess
582022The Assessment of Cognitive Reserve: A Systematic Review of the Most Used Quantitative Measurement Methods of Cognitive Reserve for AgingNogueira, Joana ; Gerardo, Bianca Salguinho ; Santana, Isabel ; Simões, Mário R. ; Freitas, Sandra articleopenAccess
5915-Mar-2023The Benson Complex Figure Test detects deficits in visuoconstruction and visual memory in symptomatic familial frontotemporal dementia: A GENFI studyJiskoot, Lize C.; Russell, Lucy L.; Peakman, Georgia; Convery, Rhian S.; Greaves, Caroline V.; Bocchetta, Martina; Poos, Jackie M.; Seelaar, Harro; Giannini, Lucia A. A.; van Swieten, John C.; van Minkelen, Rick; Pijnenburg, Yolande A. L.; Rowe, James B.; Borroni, Barbara; Galimberti, Daniela; Masellis, Mario; Tartaglia, Carmela; Finger, Elizabeth; Butler, Chris R.; Graff, Caroline; Laforce, Robert; Sánchez-Valle, Raquel ; de Mendonça, Alexandre; Moreno, Fermin; Synofzik, Matthis; Vandenberghe, Rik; Ducharme, Simon; le Ber, Isabelle; Levin, Johannes; Otto, Markus; Pasquier, Florence; Santana, Isabel ; Cash, David M.; Thomas, David; Rohrer, Jonathan D. articleopenAccess
602018The Quadruple Helix-Based Innovation Model of Reference Sites for Active and Healthy Ageing in Europe: The Ageing@Coimbra Case StudyMalva, João O. ; Amado, Alda ; Rodrigues, Alexandra; Mota-Pinto, Anabela ; Cardoso, Ana F.; Teixeira, Ana M. ; Todo-Bom, Ana ; Devesa, António; Ambrósio, António ; Cunha, António L.; Gomes, Bárbara ; Dantas, Carina; Abreu, Cidalina ; Santana, Isabel ; Bousquet, Jean ; Apóstolo, João ; Santos, Lúcia; Meneses de Almeida, Lúcio; Illario, Maddalena; Veríssimo, Rafaela ; Rodrigues, Vitor ; Veríssimo, Manuel T. articleopenAccess
612015The relevance of sociodemographic and health variables on MMSE normative dataFreitas, Sandra ; Simões, Mário Rodrigues ; Alves, Lara ; Santana, Isabel articleopenAccess
622020The Retinal Inner Plexiform Synaptic Layer Mirrors Grey Matter Thickness of Primary Visual Cortex with Increased Amyloid β Load in Early Alzheimer's DiseaseJorge, Lília; Canário, Nádia; Martins, Ricardo ; Santiago, Beatriz ; Santana, Isabel ; Quental, Hugo ; Ambrósio, Francisco ; Bernardes, Rui ; Castelo-Branco, Miguel articleopenAccess
632021The Revised Self-Monitoring Scale detects early impairment of social cognition in genetic frontotemporal dementia within the GENFI cohortFranklin, Hannah D; Russell, Lucy L; Peakman, Georgia; Greaves, Caroline V; Bocchetta, Martina; Nicholas, Jennifer; Poos, Jackie; Convery, Rhian S; Cash, David M; van Swieten, John; Jiskoot, Lize; Moreno, Fermin; Santana, Isabel ; Almeida, M. R.; Afonso, S.articleopenAccess
6429-Jan-2022The Road to Personalized Medicine in Alzheimer's Disease: The Use of Artificial IntelligenceSilva-Spínola, Anuschka; Baldeiras, Inês E. ; Arrais, Joel P. ; Santana, Isabel articleopenAccess
652019White matter hyperintensities in progranulin-associated frontotemporal dementia: A longitudinal GENFI studySudre, Carole H.; Bocchetta, Martina; Heller, Carolin; Convery, Rhian; Neason, Mollie; Moore, Katrina M.; Cash, David M.; Thomas, David L.; Woollacott, Ione O. C.; Foiani, Martha; Heslegrave, Amanda; Shafei, Rachelle; Greaves, Caroline; van Swieten, John; Moreno, Fermin; Sánchez-Valle, Raquel ; Borroni, Barbara; Laforce, Robert; Masellis, Mario; Tartaglia, Maria Carmela; Graff, Caroline; Galimberti, Daniela; Rowe, James B; Finger, Elizabeth; Synofzik, Matthis; Vandenberghe, Rik; de Mendonça, Alexandre; Tagliavini, Fabrizio ; Santana, Isabel ; Ducharme, Simon; Butler, Chris; Gerhard, Alex; Levin, Johannes; Danek, Adrian; Frisoni, Giovanni B; Sorbi, Sandro; Otto, Markus; Zetterberg, Henrik; Ourselin, Sebastien; Cardoso, M Jorge; Rohrer, Jonathan D. articleopenAccess