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Issue DateTitleAuthor(s)TypeAccess
118-May-2021Neuromodulation and neuroprotective effects of chlorogenic acids in excitatory synapses of mouse hippocampal slicesFernandes, Mara Yone D.; Dobrachinski, Fernando; Silva, Henrique B. ; Lopes, João Pedro ; Gonçalves, Francisco Q. ; Soares, Felix A A; Porciúncula, Lisiane O. ; Andrade, Geanne M; Cunha, Rodrigo A. ; Tomé, Ângelo R. articleopenAccess
231-Aug-2020The blood-brain barrier is disrupted in Machado-Joseph disease/spinocerebellar ataxia type 3: evidence from transgenic mice and human post-mortem samplesDuarte Lobo, Diana; Nobre, Rui J. ; Miranda, Catarina Sofia Oliveira ; Pereira, Dina ; Castelhano, João ; Sereno, José ; Koeppen, Arnulf ; Castelo-Branco, Miguel ; Almeida, Luís Pereira de articleopenAccess
329-Jul-2019Sources of hepatic glycogen synthesis in mice fed with glucose or fructose as the sole dietary carbohydrateJarak, Ivana ; Barosa, Cristina ; Martins, Fátima O. ; Silva, Joao C. P.; Santos, Cristiano; Belew, Getachew Debas; Rito, João; Viegas, Ivan ; Teixeira, José; Oliveira, Paulo J. ; Jones, John Griffith articleembargoedAccess
4Apr-2020Estimating pentose phosphate pathway activity from the analysis of hepatic glycogen 13 C-isotopomers derived from [U-13 C]fructose and [U-13 C]glucoseBelew, Getachew D.; Di Nunzio, Giada; Tavares, Ludgero ; Silva, Joao G.; Torres, Alejandra N.; Jones, John Griffith articleembargoedAccess
52019Establishing a Link between Endothelial Cell Metabolism and Vascular Behaviour in a Type 1 Diabetes Mouse ModelSilva, Carolina; Sampaio-Pinto, Vasco; Andrade, Sara ; Rodrigues, Ilda; Costa, Raquel; Guerreiro, Susana; Carvalho, Eugenia ; Pinto-do-Ó, Perpétua; Nascimento, Diana S; Soares, RaquelarticleopenAccess
626-Apr-2019Chronic stress triggers divergent dendritic alterations in immature neurons of the adult hippocampus, depending on their ultimate terminal fieldsDioli, Chrysoula; Patrício, Patrícia; Sousa, Nuno; Kokras, Nikolaos; Dalla, Christina; Guerreiro, Sara ; Santos-Silva, Miguel A.; Rego, Ana Cristina ; Pinto, Luísa ; Ferreiro, Elisabete ; Sotiropoulos, IoannisarticleopenAccess
72020Adenosine A2A receptors format long-term depression and memory strategies in a mouse model of Angelman syndromeMoreira-de-Sá, Ana ; Gonçalves, Francisco Q. ; Lopes, João P. ; Silva, Henrique B. ; Tomé, Ângelo R. ; Cunha, Rodrigo A. ; Canas, Paula articleopenAccess
82018Neuronal Adenosine A2A Receptors Are Critical Mediators of Neurodegeneration Triggered by ConvulsionsCanas, Paula M. ; Porciúncula, Lisiane O. ; Simões, Ana Patrícia ; Augusto, Elisabete de Oliveira ; Silva, Henrique B. ; Machado, Nuno J. ; Gonçalves, Nélio ; Alfaro, Tiago M. ; Gonçalves, Francisco Q. ; Araújo, Inês M. ; Real, Joana I. ; Coelho, Joana E. ; Andrade, Geanne M. ; Almeida, Ramiro D. ; Chen, Jiang-Fan ; Köfalvi, Attila ; Agostinho, Paula ; Cunha, Rodrigo A. articleopenAccess
916-Apr-2020Glioblastoma hijacks microglial gene expression to support tumor growthMaas, Sybren L. N.; Abels, Erik R.; Van De Haar, Lieke L.; Zhang, Xuan; Morsett, Liza; Sil, Srinjoy; Guedes, Joana ; Sen, Pritha; Prabhakar, Shilpa; Hickman, Suzanne E.; Lai, Charles P.; Ting, David T.; Breakefield, Xandra O.; Broekman, Marike L. D.; El Khoury, JosepharticleopenAccess
1022-Mar-2021Synaptotagmin-7 places dense-core vesicles at the cell membrane to promote Munc13-2- and Ca2+-dependent primingTawfik, Bassam; Martins, Joana S; Houy, Sébastien; Imig, Cordelia; Pinheiro, Paulo S. ; Wojcik, Sonja M; Brose, Nils; Cooper, Benjamin H; Sørensen, Jakob BalslevarticleopenAccess
112018Can we induce spermatogenesis in the domestic cat using an in vitro tissue culture approach?Silva, Andreia F. ; Escada-Rebelo, Sara ; Amaral, Sandra ; Santos Tavares, Renata ; Schlatt, Stefan; Ramalho-Santos, João ; Mota, Paula C. articleopenAccess
1216-Jul-2018The exercise sex gap and the impact of the estrous cycle on exercise performance in miceAguiar, Aderbal S. ; Speck, Ana Elisa ; Amaral, Inês M. ; Canas, Paula M. ; Cunha, Rodrigo A. articleopenAccess
132-Oct-2017Crosstalk between glial and glioblastoma cells triggers the "go-or-grow" phenotype of tumor cellsOliveira, Ana Isabel; Anjo, Sandra I. ; Vieira de Castro, Joana; Serra, Sofia C.; Salgado, António J. ; Manadas, Bruno ; Costa, Bruno M.articleopenAccess
1419-Jan-2017Glucocorticoid receptor signalling activates YAP in breast cancerSorrentino, Giovanni; Ruggeri, Naomi; Zannini, Alessandro; Ingallina, Eleonora; Bertolio, Rebecca; Marotta, Carolina; Neri, Carmelo; Cappuzzello, Elisa; Forcato, Mattia; Rosato, Antonio; Mano, Miguel ; Bicciato, Silvio; Del Sal, GianninoarticleopenAccess
15Oct-2017Transcription factor NRF2 controls the fate of neural stem cells in the subgranular zone of the hippocampusRobledinos-Antón, Natalia; Rojo, Ana I; Ferreiro, Elisabete ; Núñez, Ángel; Krause, Karl-Heinz; Jaquet, Vincent; Cuadrado, AntonioarticleopenAccess
1625-Aug-2017The Parkinson's disease-associated GPR37 receptor interacts with striatal adenosine A2A receptor controlling its cell surface expression and function in vivoMorató, Xavier; Luján, Rafael; López-Cano, Marc; Gandía, Jorge; Stagljar, Igor; Watanabe, Masahiko; Cunha, Rodrigo A. ; Fernández-Dueñas, Víctor; Ciruela, Francisco articleopenAccess
1710-Jun-2016Oncostatin M promotes excitotoxicity by inhibiting glutamate uptake in astrocytes: implications in HIV-associated neurotoxicityMoidunny, Shamsudheen; Matos, Marco ; Wesseling, Evelyn; Banerjee, Santanu; Volsky, David J.; Cunha, Rodrigo A.; Agostinho, Paula ; Boddeke, Hendrikus W.; Roy, SabitaarticleopenAccess
1827-Sep-2016Blunted dynamics of adenosine A2A receptors is associated with increased susceptibility to Candida albicans infection in the elderlyRodrigues, Lisa ; Miranda, Isabel M.; Andrade, Geanne M. ; Mota, Marta ; Cortes, Luísa ; Rodrigues, Acácio G.; Cunha, Rodrigo A. ; Gonçalves, Teresa articleopenAccess
1921-Jul-2015Reduced α-MSH Underlies Hypothalamic ER-Stress-Induced Hepatic GluconeogenesisSchneeberger, Marc; Gómez-Valadés, Alicia G.; Altirriba, Jordi; Sebastián, David; Ramírez, Sara; Garcia, Ainhoa; Esteban, Yaiza; Drougard, Anne; Ferrés-Coy, Albert; Bortolozzi, Analía; Garcia-Roves, Pablo M.; Jones, John G. ; Manadas, Bruno ; Zorzano, Antonio; Gomis, Ramon; Claret, MarcarticleopenAccess
202015Nitric Oxide Regulates Neurogenesis in the Hippocampus following SeizuresCarreira, Bruno P. ; Santos, Daniela F; Santos, Ana I. ; Carvalho, Caetana M. ; Araújo, InêsarticleopenAccess
212017Anti-Inflammatory Strategy for M2 Microglial Polarization Using Retinoic Acid-Loaded NanoparticlesMachado-Pereira, Marta; Santos, Tiago ; Ferreira, Lino ; Bernardino, Liliana ; Ferreira, RaquelarticleopenAccess
2230-Jan-2013Activation of microglial cells triggers a release of brain-derived neurotrophic factor (BDNF) inducing their proliferation in an adenosine A2A receptor-dependent manner: A2A receptor blockade prevents BDNF release and proliferation of microgliaGomes, Catarina ; Ferreira, Raquel ; George, Jimmy ; Sanches, Rui; Rodrigues, Diana I. ; Gonçalves, Nélio ; Cunha, Rodrigo A. articleopenAccess
232013Differential contribution of the guanylyl cyclase-cyclic GMP-protein kinase G pathway to the proliferation of neural stem cells stimulated by nitric oxideCarreira, Bruno P. ; Morte, Maria Inês ; Lourenço, Ana Sofia ; Santos, Ana Isabel ; Inácio, Ângela ; Ambrósio, A. Francisco ; Carvalho, Caetana M. ; Araújo, Inês M. articleopenAccess
242013Silencing mutant ataxin-3 rescues motor deficits and neuropathology in Machado-Joseph disease transgenic miceNóbrega, Clévio ; Nascimento-Ferreira, Isabel ; Onofre, Isabel ; Albuquerque, David ; Hirai, Hirokazu; Déglon, Nicole ; Almeida, Luís Pereira de articleopenAccess
252013Brain-derived neurotrophic factor promotes vasculature-associated migration of neuronal precursors toward the ischemic striatumGrade, Sofia ; Weng, Yuan C.; Snapyan, Marina; Kriz, Jasna; Malva, João O. ; Saghatelyan, ArmenarticleopenAccess
262013Activation of type 1 cannabinoid receptor (CB1R) promotes neurogenesis in murine subventricular zone cell culturesXapelli, Sara Alves ; Agasse, Fabienne ; Sardà-Arroyo, Laura; Bernardino, Liliana ; Santos, Tiago ; Ribeiro, Filipa F.; Valero, Jorge ; Bragança, José ; Schitine, Clarissa; de Melo Reis, Ricardo A; Sebastião, Ana M. ; Malva, João O. articleopenAccess
278-May-2012Histamine modulates microglia functionFerreira, Raquel ; Santos, Tiago ; Gonçalves, Joana ; Baltazar, Graça ; Ferreira, Lino ; Agasse, Fabienne ; Bernardino, Liliana articleopenAccess
282012A new strategy based on SmRho protein loaded chitosan nanoparticles as a candidate oral vaccine against schistosomiasisOliveira, Carolina R.; Rezende, Cíntia M. F.; Silva, Marina R.; Pêgo, Ana Paula; Borges, Olga ; Goes, Alfredo M.articleopenAccess
292012Oral vaccination based on DNA-chitosan nanoparticles against Schistosoma mansoni infectionOliveira, Carolina R.; Rezende, Cíntia M. F.; Silva, Marina R.; Borges, Olga M. ; Pêgo, Ana P.; Goes, Alfredo M.articleopenAccess
3029-Nov-2010Functional and pathogenic differences of Th1 and Th17 cells in experimental autoimmune encephalomyelitisDomingues, Helena S. ; Mues, Marsilius; Lassmann, Hans; Wekerle, Hartmut; Krishnamoorthy, GurumoorthyarticleopenAccess
31Jul-2023Hypothalamic JNK1-hepatic fatty acid synthase axis mediates a metabolic rewiring that prevents hepatic steatosis in male mice treated with olanzapine via intraperitoneal: Additional effects of PTP1B inhibitionFerreira, Vitor; Folgueira, Cintia; García-Altares, María; Guillén, Maria; Ruíz-Rosario, Mónica; DiNunzio, Giada ; Garcia-Martinez, Irma; Alen, Rosa; Bookmeyer, Christoph; Jones, John G. ; Cigudosa, Juan C.; López-Larrubia, Pilar; Correig-Blanchar, Xavier; Davis, Roger J.; Sabio, Guadalupe; Rada, Patricia; Valverde, Angela M. articleopenAccess
329-Feb-2023Comparative Analysis of Retinal Organotypic Cultures and In Vivo Axotomized RetinasGonzález-Riquelme, María José; Lucas-Ruiz, Fernando; Galindo-Romero, Caridad; Boia, Raquel ; Ambrósio, António Francisco ; Vidal-Sanz, Manuel; Santiago, Ana Raquel ; Agudo-Barriuso, MartaarticleopenAccess
332023ECSIT is essential for RANKL-induced stimulation of mitochondria in osteoclasts and a target for the anti-osteoclastogenic effects of estrogensCarvalho, Adriana Marques ; Sardão, Vilma A. ; Kim, Ha-Neui; Almeida, Maria SarticleopenAccess
34Dec-2023The striatum drives the ergogenic effects of caffeinede Bem Alves, Ana Cristina; Speck, Ana Elisa ; Farias, Hémelin Resende; Martins, Leo Meira; Dos Santos, Naiara Souza; Pannata, Gabriela; Tavares, Ana Paula Gomes ; de Oliveira, Jade; Tomé, Ângelo R. ; Cunha, Rodrigo A. ; Aguiar, Aderbal S. articleopenAccess
359-Mar-2020Endophilin-A coordinates priming and fusion of neurosecretory vesicles via intersectinGowrisankaran, Sindhuja; Houy, Sébastien; Del Castillo, Johanna G Peña; Steubler, Vicky; Gelker, Monika; Kroll, Jana; Pinheiro, Paulo S. ; Schwitters, Dirk; Halbsgut, Nils; Pechstein, Arndt; van Weering, Jan R. T.; Maritzen, Tanja; Haucke, Volker; Raimundo, Nuno ; Sørensen, Jakob B.; Milosevic, Ira articleopenAccess
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