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Issue DateTitleAuthor(s)TypeAccess
11-Oct-2020SVEP1 as a Genetic Modifier of TEK-Related Primary Congenital GlaucomaYoung, Terri L.; Whisenhunt, Kristina N.; Jin, Jing; LaMartina, Sarah M.; Martin, Sean M.; Souma, Tomokazu; Limviphuvadh, Vachiranee; Suri, Fatemeh; Souzeau, Emmanuelle; Zhang, Xue; Dan, Yongwook; Anagnos, Evie; Carmona, Susana ; Jody, Nicole M.; Stangel, Nickie; Higuchi, Emily C.; Huang, Samuel J.; Siggs, Owen M.; Simões, Maria José; Lawson, Brendan M.; Martin, Jacob S.; Elahi, Elahe; Narooie-Nejad, Mehrnaz; Motlagh, Behzad Fallahi; Quaggin, Susan E.; Potter, Heather D.; Silva, Eduardo D. ; Craig, Jamie E.; Egas, Conceição ; Maroofian, Reza; Maurer-Stroh, Sebastian; Bradfield, Yasmin S.; Tompson, Stuart W.articleopenAccess
27-Jul-2020Neurofilaments in spinocerebellar ataxia type 3: blood biomarkers at the preataxic and ataxic stage in humans and miceWilke, Carlo; Haas, Eva; Reetz, Kathrin; Faber, Jennifer; Garcia-Moreno, Hector; Santana, Magda M. ; van de Warrenburg, Bart; Hengel, Holger; Lima, Manuela ; Filla, Alessandro; Durr, Alexandra; Melegh, Bela; Masciullo, Marcella; Infante, Jon; Giunti, Paola; Neumann, Manuela; de Vries, Jeroen; Almeida, Luís Pereira de ; Rakowicz, Maria; Jacobi, Heike; Schüle, Rebecca; Kaeser, Stephan A.; Kuhle, Jens; Klockgether, Thomas; Schöls, Ludger; Barro, Christian; Hübener-Schmid, Jeannette; Synofzik, MatthisarticleopenAccess
318-May-2021Neuromodulation and neuroprotective effects of chlorogenic acids in excitatory synapses of mouse hippocampal slicesFernandes, Mara Yone D.; Dobrachinski, Fernando; Silva, Henrique B. ; Lopes, João Pedro ; Gonçalves, Francisco Q. ; Soares, Felix A A; Porciúncula, Lisiane O. ; Andrade, Geanne M; Cunha, Rodrigo A. ; Tomé, Ângelo R. articleopenAccess
431-Aug-2020The blood-brain barrier is disrupted in Machado-Joseph disease/spinocerebellar ataxia type 3: evidence from transgenic mice and human post-mortem samplesDuarte Lobo, Diana; Nobre, Rui J. ; Miranda, Catarina Sofia Oliveira ; Pereira, Dina ; Castelhano, João ; Sereno, José ; Koeppen, Arnulf ; Castelo-Branco, Miguel ; Almeida, Luís Pereira de articleopenAccess
5Nov-2020Sulforaphane prevents age-associated cardiac and muscular dysfunction through Nrf2 signalingBose, Chhanda; Alves, Inês ; Singh, Preeti; Palade, Philip T.; Carvalho, Eugenia ; Børsheim, Elisabet; Jun, Se-Ran; Cheema, Amrita; Boerma, Marjan; Awasthi, Sanjay; Singh, Sharda P.articleopenAccess
68-Mar-2017Histone Deacetylase Inhibitors Protect Against Pyruvate Dehydrogenase Dysfunction in Huntington's DiseaseNaia, Luana ; Cunha-Oliveira, Teresa ; Rodrigues, Joana ; Rosenstock, Tatiana R. ; Oliveira, Ana ; Ribeiro, Márcio ; Carmo, Catarina ; Oliveira-Sousa, Sofia I. ; Duarte, Ana I. ; Hayden, Michael R. ; Rego, A. Cristina articleopenAccess
729-Jul-2019Sources of hepatic glycogen synthesis in mice fed with glucose or fructose as the sole dietary carbohydrateJarak, Ivana ; Barosa, Cristina ; Martins, Fátima O. ; Silva, Joao C. P.; Santos, Cristiano; Belew, Getachew Debas; Rito, João; Viegas, Ivan ; Teixeira, José; Oliveira, Paulo J. ; Jones, John Griffith articleembargoedAccess
8Apr-2020Estimating pentose phosphate pathway activity from the analysis of hepatic glycogen 13 C-isotopomers derived from [U-13 C]fructose and [U-13 C]glucoseBelew, Getachew D.; Di Nunzio, Giada; Tavares, Ludgero ; Silva, Joao G.; Torres, Alejandra N.; Jones, John Griffith articleembargoedAccess
92013Therapeutic Potential of Caspofungin Combined with Trimethoprim-Sulfamethoxazole for Pneumocystis Pneumonia: A Pilot Study in MiceLobo, Maria Luísa ; Esteves, Francisco ; Sousa, Bruno de ; Cardoso, Fernando ; Cushion, Melanie T. ; Antunes, Francisco ; Matos, Olga articleopenAccess
107-Aug-2020Neuronal adenosine A2A receptors signal ergogenic effects of caffeineAguiar, Aderbal S. ; Speck, Ana Elisa ; Canas, Paula M. ; Cunha, Rodrigo A. articleopenAccess
1113-Nov-2019Retinal thinning of inner sub-layers is associated with cortical atrophy in a mouse model of Alzheimer's disease: a longitudinal multimodal in vivo studyChiquita, Samuel; Campos, Elisa J. ; Castelhano, João ; Ribeiro, Mário ; Sereno, José ; Moreira, Paula I. ; Castelo-Branco, Miguel ; Ambrósio, António Francisco articleopenAccess
122019Establishing a Link between Endothelial Cell Metabolism and Vascular Behaviour in a Type 1 Diabetes Mouse ModelSilva, Carolina; Sampaio-Pinto, Vasco; Andrade, Sara ; Rodrigues, Ilda; Costa, Raquel; Guerreiro, Susana; Carvalho, Eugenia ; Pinto-do-Ó, Perpétua; Nascimento, Diana S; Soares, RaquelarticleopenAccess
1326-Apr-2019Chronic stress triggers divergent dendritic alterations in immature neurons of the adult hippocampus, depending on their ultimate terminal fieldsDioli, Chrysoula; Patrício, Patrícia; Sousa, Nuno; Kokras, Nikolaos; Dalla, Christina; Guerreiro, Sara ; Santos-Silva, Miguel A.; Rego, Ana Cristina ; Pinto, Luísa ; Ferreiro, Elisabete ; Sotiropoulos, IoannisarticleopenAccess
149-Apr-2019microRNA-155 inhibition restores Fibroblast Growth Factor 7 expression in diabetic skin and decreases wound inflammationMoura, João ; Sørensen, Anja; Leal, Ermelindo ; Svendsen, Rikke; Carvalho, Lina ; Willemoes, Rie Juul; Jørgensen, Per Trolle; Jenssen, Håvard; Wengel, Jesper; Dalgaard, Louise Torp; Carvalho, Eugenia articleopenAccess
152018Neuronal Adenosine A2A Receptors Are Critical Mediators of Neurodegeneration Triggered by ConvulsionsCanas, Paula M. ; Porciúncula, Lisiane O. ; Simões, Ana Patrícia ; Augusto, Elisabete de Oliveira ; Silva, Henrique B. ; Machado, Nuno J. ; Gonçalves, Nélio ; Alfaro, Tiago M. ; Gonçalves, Francisco Q. ; Araújo, Inês M. ; Real, Joana I. ; Coelho, Joana E. ; Andrade, Geanne M. ; Almeida, Ramiro D. ; Chen, Jiang-Fan ; Köfalvi, Attila ; Agostinho, Paula ; Cunha, Rodrigo A. articleopenAccess
162018Reactive Oxygen Species Deficiency Due to Ncf1-Mutation Leads to Development of Adenocarcinoma and Metabolomic and Lipidomic Remodeling in a New Mouse Model of Dextran Sulfate Sodium-Induced ColitisCarvalho, Lina ; Gomes, Joana R. M. ; Tavares, Ludgero C. ; Xavier, Ana R.; Klika, Karel D.; Holmdahl, Rikard; Carvalho, Rui A. ; Carneiro, Maria Margarida Souto articleopenAccess
175-Jan-2021Intermittent Hypoxic Conditioning Rescues Cognition and Mitochondrial Bioenergetic Profile in the Triple Transgenic Mouse Model of Alzheimer's DiseaseCorreia, Sónia C. ; Machado, Nuno J. ; Alves, Marco G; Oliveira, Pedro F. ; Moreira, Paula I. articleopenAccess
182018Considerations and Pitfalls in Selecting the Drug Vehicles for Evaluation of New Drug Candidates: Focus on in vivo Pharmaco-Toxicological Assays Based on the Rotarod Performance TestMatias, Mariana ; Silvestre, Samuel ; Falcão, Amílcar ; Alves, Gilberto articleopenAccess
1916-Apr-2020Glioblastoma hijacks microglial gene expression to support tumor growthMaas, Sybren L. N.; Abels, Erik R.; Van De Haar, Lieke L.; Zhang, Xuan; Morsett, Liza; Sil, Srinjoy; Guedes, Joana ; Sen, Pritha; Prabhakar, Shilpa; Hickman, Suzanne E.; Lai, Charles P.; Ting, David T.; Breakefield, Xandra O.; Broekman, Marike L. D.; El Khoury, JosepharticleopenAccess
2025-Jun-2021The Alterations of Mitochondrial Function during NAFLD Progression-An Independent Effect of Mitochondrial ROS ProductionSimões, Inês C M; Amorim, Ricardo ; Teixeira, José; Karkucinska-Wieckowska, Agnieszka; Carvalho, Adriana ; Pereira, Susana P; Simões, Rui F. ; Szymanska, Sylwia; Dąbrowski, Michał; Janikiewicz, Justyna; Dobrzyń, Agnieszka; Oliveira, Paulo J; Potes, Yaiza; Wieckowski, Mariusz R. articleopenAccess
212018MicroRNA-124-loaded nanoparticles increase survival and neuronal differentiation of neural stem cells in vitro but do not contribute to stroke outcome in vivoSaraiva, Cláudia; Talhada, Daniela; Rai, Akhilesh ; Ferreira, Raquel; Ferreira, Lino ; Bernardino, Liliana ; Ruscher, Karsten articleopenAccess
222018Can we induce spermatogenesis in the domestic cat using an in vitro tissue culture approach?Silva, Andreia F. ; Escada-Rebelo, Sara ; Amaral, Sandra ; Santos Tavares, Renata ; Schlatt, Stefan; Ramalho-Santos, João ; Mota, Paula C. articleopenAccess
2316-Jul-2018The exercise sex gap and the impact of the estrous cycle on exercise performance in miceAguiar, Aderbal S. ; Speck, Ana Elisa ; Amaral, Inês M. ; Canas, Paula M. ; Cunha, Rodrigo A. articleopenAccess
2412-Jun-2018Dual Therapy with Liraglutide and Ghrelin Promotes Brain and Peripheral Energy Metabolism in the R6/2 Mouse Model of Huntington's DiseaseDuarte, Ana I. ; Sjögren, Marie; Santos, Maria S. ; Oliveira, Catarina R. ; Moreira, Paula I. ; Björkqvist, MariaarticleopenAccess
255-Dec-2017Control of Huntington's Disease-Associated Phenotypes by the Striatum-Enriched Transcription Factor Foxp2Hachigian, Lea J.; Carmona, Vitor ; Fenster, Robert J.; Kulicke, Ruth; Heilbut, Adrian; Sittler, Annie; Almeida, Luís Pereira de ; Mesirov, Jill P.; Gao, Fan; Kolaczyk, Eric D.; Heiman, MyriamarticleopenAccess
262017Testing the excitation/inhibition imbalance hypothesis in a mouse model of the autism spectrum disorder: in vivo neurospectroscopy and molecular evidence for regional phenotypesGonçalves, Joana ; Violante, Inês R. ; Sereno, José ; Leitão, Ricardo A. ; Cai, Ying; Abrunhosa, Antero ; Silva, Ana Paula ; Silva, Alcino J.; Castelo-Branco, Miguel articleopenAccess
2711-May-2017Prolonged intracellular accumulation of light-inducible nanoparticles in leukemia cells allows their remote activationBoto, Carlos ; Quartin, Emanuel ; Cai, Yijun; Martín-Lorenzo, Alberto; Cenador, María Begoña García; Pinto, Sandra ; Gupta, Rajeev; Enver, Tariq; Sánchez-García, Isidro; Hong, Dengli; Neves, Ricardo Pires das ; Ferreira, Lino articleopenAccess
2825-Aug-2017The Parkinson's disease-associated GPR37 receptor interacts with striatal adenosine A2A receptor controlling its cell surface expression and function in vivoMorató, Xavier; Luján, Rafael; López-Cano, Marc; Gandía, Jorge; Stagljar, Igor; Watanabe, Masahiko; Cunha, Rodrigo A. ; Fernández-Dueñas, Víctor; Ciruela, Francisco articleopenAccess
2924-Oct-2017Ghrelin rescues skeletal muscle catabolic profile in the R6/2 mouse model of Huntington's diseaseSjögren, Marie; Duarte, Ana I. ; McCourt, Andrew C.; Shcherbina, Liliya; Wierup, Nils; Björkqvist, MariaarticleopenAccess
3021-Oct-2016Natural killer cell-based adoptive immunotherapy eradicates and drives differentiation of chemoresistant bladder cancer stem-like cellsFerreira-Teixeira, Margarida ; Paiva-Oliveira, Daniela ; Parada, Belmiro ; Alves, Vera ; Sousa, Vítor ; Chijioke, Obinna; Münz, Christian; Reis, Flávio ; Rodrigues-Santos, Paulo ; Gomes, Célia articleopenAccess
3127-Sep-2016Blunted dynamics of adenosine A2A receptors is associated with increased susceptibility to Candida albicans infection in the elderlyRodrigues, Lisa ; Miranda, Isabel M.; Andrade, Geanne M. ; Mota, Marta ; Cortes, Luísa ; Rodrigues, Acácio G.; Cunha, Rodrigo A. ; Gonçalves, Teresa articleopenAccess
3221-Jul-2015Reduced α-MSH Underlies Hypothalamic ER-Stress-Induced Hepatic GluconeogenesisSchneeberger, Marc; Gómez-Valadés, Alicia G.; Altirriba, Jordi; Sebastián, David; Ramírez, Sara; Garcia, Ainhoa; Esteban, Yaiza; Drougard, Anne; Ferrés-Coy, Albert; Bortolozzi, Analía; Garcia-Roves, Pablo M.; Jones, John G. ; Manadas, Bruno ; Zorzano, Antonio; Gomis, Ramon; Claret, MarcarticleopenAccess
332015Nitric Oxide Regulates Neurogenesis in the Hippocampus following SeizuresCarreira, Bruno P. ; Santos, Daniela F; Santos, Ana I. ; Carvalho, Caetana M. ; Araújo, InêsarticleopenAccess
342014Behavioral phenotyping of Parkin-deficient mice: looking for early preclinical features of Parkinson's diseaseRial, Daniel ; Castro, Adalberto A.; Machado, Nuno J. ; Garção, Pedro ; Gonçalves, Francisco Q. ; Silva, Henrique B. ; Tomé, Ângelo R. ; Köfalvi, Attila ; Corti, Olga; Raisman-Vozari, Rita; Cunha, Rodrigo A. ; Prediger, Rui D.articleopenAccess
352014Deficient production of reactive oxygen species leads to severe chronic DSS-induced colitis in Ncf1/p47phox-mutant miceRodrigues-Sousa, Tiago ; Ladeirinha, Ana Filipa Ferreira ; Santiago, Ana Raquel ; Carvalheiro, Helena ; Raposo, Bruno; Alarcão, Ana ; Cabrita, António ; Holmdahl, Rikard; Carvalho, Lina ; Carneiro, M. Margarida Souto articleopenAccess
362013Brain-derived neurotrophic factor promotes vasculature-associated migration of neuronal precursors toward the ischemic striatumGrade, Sofia ; Weng, Yuan C.; Snapyan, Marina; Kriz, Jasna; Malva, João O. ; Saghatelyan, ArmenarticleopenAccess
374-Apr-2012Therapeutic implications of an enriched cancer stem-like cell population in a human osteosarcoma cell lineMartins-Neves, Sara R. ; Lopes, Áurio ; Carmo, Anália do ; Paiva, Artur A. ; Simões, Paulo C.; Abrunhosa, Antero ; Gomes, Célia M. F. articleopenAccess
382012Caffeine consumption prevents diabetes-induced memory impairment and synaptotoxicity in the hippocampus of NONcZNO10/LTJ miceDuarte, João M. N. ; Agostinho, Paula M. ; Carvalho, Rui A. ; Cunha, Rodrigo A. articleopenAccess
3926-Apr-2023Neurobehavioral sex-related differences in Nf1+/- mice: female show a "camouflaging"-type behaviorSantos, Sofia ; Martins, Beatriz ; Sereno, José ; Martins, João ; Castelo-Branco, Miguel ; Gonçalves, Joana articleopenAccess
405-Apr-2023Lateral septum adenosine A2A receptors control stress-induced depressive-like behaviors via signaling to the hypothalamus and habenulaWang, Muran; Li, Peijun; Li, Zewen; Silva, Beatriz S. da ; Zheng, Wu; Xiang, Zhenghua; He, Yan; Xu, Tao; Cordeiro, Cristina; Deng, Lu; Dai, Yuwei; Ye, Mengqian; Lin, Zhiqing; Zhou, Jianhong; Zhou, Xuzhao; Ye, Fenfen; Cunha, Rodrigo A. ; Chen, Jiang-Fan ; Guo, WeiarticleopenAccess
41Jul-2023Hypothalamic JNK1-hepatic fatty acid synthase axis mediates a metabolic rewiring that prevents hepatic steatosis in male mice treated with olanzapine via intraperitoneal: Additional effects of PTP1B inhibitionFerreira, Vitor; Folgueira, Cintia; García-Altares, María; Guillén, Maria; Ruíz-Rosario, Mónica; DiNunzio, Giada ; Garcia-Martinez, Irma; Alen, Rosa; Bookmeyer, Christoph; Jones, John G. ; Cigudosa, Juan C.; López-Larrubia, Pilar; Correig-Blanchar, Xavier; Davis, Roger J.; Sabio, Guadalupe; Rada, Patricia; Valverde, Angela M. articleopenAccess
429-Feb-2023Comparative Analysis of Retinal Organotypic Cultures and In Vivo Axotomized RetinasGonzález-Riquelme, María José; Lucas-Ruiz, Fernando; Galindo-Romero, Caridad; Boia, Raquel ; Ambrósio, António Francisco ; Vidal-Sanz, Manuel; Santiago, Ana Raquel ; Agudo-Barriuso, MartaarticleopenAccess
43Dec-2023The striatum drives the ergogenic effects of caffeinede Bem Alves, Ana Cristina; Speck, Ana Elisa ; Farias, Hémelin Resende; Martins, Leo Meira; Dos Santos, Naiara Souza; Pannata, Gabriela; Tavares, Ana Paula Gomes ; de Oliveira, Jade; Tomé, Ângelo R. ; Cunha, Rodrigo A. ; Aguiar, Aderbal S. articleopenAccess
444-Jan-2023Effects of Chronic Caffeine Consumption on Synaptic Function, Metabolism and Adenosine Modulation in Different Brain AreasLopes, Cátia R. ; Oliveira, Andreia; Gaspar, Ingride L. ; Rodrigues, Matilde S. ; Santos, Joana ; Szabó, Eszter; Silva, Henrique B. ; Tomé, Ângelo R. ; Canas, Paula M. ; Agostinho, Paula M. ; Carvalho, Rui A. ; Cunha, Rodrigo A. ; Simões, Ana Patrícia ; Lopes, João Pedro ; Ferreira, Samira G. articleopenAccess
459-Mar-2020Endophilin-A coordinates priming and fusion of neurosecretory vesicles via intersectinGowrisankaran, Sindhuja; Houy, Sébastien; Del Castillo, Johanna G Peña; Steubler, Vicky; Gelker, Monika; Kroll, Jana; Pinheiro, Paulo S. ; Schwitters, Dirk; Halbsgut, Nils; Pechstein, Arndt; van Weering, Jan R. T.; Maritzen, Tanja; Haucke, Volker; Raimundo, Nuno ; Sørensen, Jakob B.; Milosevic, Ira articleopenAccess
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