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Issue DateTitleAuthor(s)TypeAccess
12022Cerebellar morphometric and spectroscopic biomarkers for Machado-Joseph DiseaseMiranda, Catarina Oliveira ; Nobre, Rui Jorge ; Paiva, Vítor Hugo ; Duarte, João Valente ; Castelhano, João ; Petrella, Lorena Itati ; Sereno, José ; Santana, Magda ; Afonso, Sónia ; Januário, Cristina ; Castelo Branco, Miguel ; Almeida, Luís Pereira de articleopenAccess
217-Jan-2020SLMP53-1 Inhibits Tumor Cell Growth through Regulation of Glucose Metabolism and Angiogenesis in a P53-Dependent MannerRamos, Helena; Calheiros, Juliana; Almeida, Joana; Barcherini, Valentina; Santos, Sónia ; Carvalho, Alexandra T. P. ; Santos, Maria M. M.; Saraiva, LucíliaarticleopenAccess
321-Oct-2020Calcium Modulation, Anti-Oxidant and Anti-Inflammatory Effect of Skin Allergens Targeting the Nrf2 Signaling Pathway in Alzheimer's Disease Cellular ModelsSilva, Ana ; Pereira, Marta ; Carrascal, Mylène A. ; Brites, Gonçalo; Neves, Bruno; Moreira, Patrícia ; Resende, Rosa ; Silva, Maria Manuel ; Santos, Armanda E. ; Pereira, Cláudia ; Cruz, Maria Teresa articleopenAccess
41-Oct-2020SVEP1 as a Genetic Modifier of TEK-Related Primary Congenital GlaucomaYoung, Terri L.; Whisenhunt, Kristina N.; Jin, Jing; LaMartina, Sarah M.; Martin, Sean M.; Souma, Tomokazu; Limviphuvadh, Vachiranee; Suri, Fatemeh; Souzeau, Emmanuelle; Zhang, Xue; Dan, Yongwook; Anagnos, Evie; Carmona, Susana ; Jody, Nicole M.; Stangel, Nickie; Higuchi, Emily C.; Huang, Samuel J.; Siggs, Owen M.; Simões, Maria José; Lawson, Brendan M.; Martin, Jacob S.; Elahi, Elahe; Narooie-Nejad, Mehrnaz; Motlagh, Behzad Fallahi; Quaggin, Susan E.; Potter, Heather D.; Silva, Eduardo D. ; Craig, Jamie E.; Egas, Conceição ; Maroofian, Reza; Maurer-Stroh, Sebastian; Bradfield, Yasmin S.; Tompson, Stuart W.articleopenAccess
56-Mar-2020Characterization and Cytotoxicity Assessment of the Lipophilic Fractions of Different Morphological Parts of Acacia dealbataOliveira, Cátia S. D.; Moreira, Patrícia ; Resende, Judite; Cruz, Maria T. ; Pereira, Cláudia F. ; Silva, Artur M. S. ; Santos, Sónia A. O. ; Silvestre, Armando J. D. articleopenAccess
67-Jul-2020Neurofilaments in spinocerebellar ataxia type 3: blood biomarkers at the preataxic and ataxic stage in humans and miceWilke, Carlo; Haas, Eva; Reetz, Kathrin; Faber, Jennifer; Garcia-Moreno, Hector; Santana, Magda M. ; van de Warrenburg, Bart; Hengel, Holger; Lima, Manuela ; Filla, Alessandro; Durr, Alexandra; Melegh, Bela; Masciullo, Marcella; Infante, Jon; Giunti, Paola; Neumann, Manuela; de Vries, Jeroen; Almeida, Luís Pereira de ; Rakowicz, Maria; Jacobi, Heike; Schüle, Rebecca; Kaeser, Stephan A.; Kuhle, Jens; Klockgether, Thomas; Schöls, Ludger; Barro, Christian; Hübener-Schmid, Jeannette; Synofzik, MatthisarticleopenAccess
7Dec-2021The transcription factor Ndt80 is a repressor of Candida parapsilosis virulence attributesBranco, Joana; Martins-Cruz, Cláudia; Rodrigues, Lisa ; Silva, Raquel M.; Araújo-Gomes, Nuno; Gonçalves, Teresa ; Miranda, Isabel M.; Rodrigues, Acácio G.articleopenAccess
831-Aug-2020The blood-brain barrier is disrupted in Machado-Joseph disease/spinocerebellar ataxia type 3: evidence from transgenic mice and human post-mortem samplesDuarte Lobo, Diana; Nobre, Rui J. ; Miranda, Catarina Sofia Oliveira ; Pereira, Dina ; Castelhano, João ; Sereno, José ; Koeppen, Arnulf ; Castelo-Branco, Miguel ; Almeida, Luís Pereira de articleopenAccess
92015Analysis of pro-apoptotic protein trafficking to and from mitochondriaVega-Naredo, Ignacio ; Cunha-Oliveira, Teresa ; Serafim, Teresa L. ; Sardão, Vilma A. ; Oliveira, Paulo J. articleopenAccess
104-May-2016Determination of Metabolic Viability and Cell Mass Using a Tandem Resazurin/Sulforhodamine B AssaySilva, Filomena S. G. ; Starostina, Irina G. ; Ivanova, Vilena V. ; Rizvanov, Albert A. ; Oliveira, Paulo J. ; Pereira, Susana P. articleopenAccess
1128-Sep-2017Antimicrobial peptide-gold nanoscale therapeutic formulation with high skin regenerative potentialComune, Michela ; Rai, Akhilesh ; Chereddy, Kiran K; Pinto, Sandra; Aday, Sezin; Ferreira, André F; Zonari, Alessandra ; Blersch, Josephine; Cunha, Rodrigo Pinto Antunes da ; Rodrigues, Ricardo; Lerma, Juan ; Simões, Pedro Nuno ; Préat, Veronique; Ferreira, Lino articleopenAccess
122016Highly active ozonides selected against drug resistant malariaLobo, Lis ; Sousa, Bruno de ; Cabral, Lília ; Cristiano, Maria L. S. ; Nogueira, Fátima articleopenAccess
134-Mar-2021Cytotoxic Mechanism of Sphaerodactylomelol, an Uncommon Bromoditerpene Isolated from Sphaerococcus coronopifoliusAlves, Celso ; Silva, Joana; Pinteus, Susete; Alonso, Eva; Alvariño, Rebeca; Duarte, Adriana ; Marmitt, Diorge; Goettert, Márcia Inês; Gaspar, Helena ; Alfonso, Amparo; Alpoim, Maria C. ; Botana, Luis M.; Pedrosa, RuiarticleopenAccess
1429-Apr-2020Standardised comparison of limonene-derived monoterpenes identifies structural determinants of anti-inflammatory activitySousa, Cátia ; Leitão, Alcino Jorge ; Neves, Bruno Miguel ; Judas, Fernando ; Cavaleiro, Carlos ; Mendes, Alexandrina F. articleopenAccess
1510-Apr-2020Giardia lamblia Decreases NF-κB p65RelA Protein Levels and Modulates LPS-Induced Pro-Inflammatory Response in MacrophagesFaria, Clarissa Perez ; Neves, Bruno Miguel ; Lourenço, Ágata ; Cruz, Maria Teresa ; Martins, João D. ; Silva, Ana ; Pereira, Sónia ; Sousa, Maria do Céu articleopenAccess
1623-Jul-2019Synaptogenesis Stimulates a Proteasome-Mediated Ribosome Reduction in AxonsCosta, Rui O. ; Martins, Helena ; Martins, Luís F. ; Cwetsch, Andrzej W; Mele, Miranda ; Pedro, Joana R. ; Tomé, Diogo ; Jeon, Noo Li; Cancedda, Laura; Jaffrey, Samie R.; Almeida, Ramiro D. articleopenAccess
1722-Mar-2019Sterol regulatory element binding protein 1 couples mechanical cues and lipid metabolismBertolio, Rebecca; Napoletano, Francesco; Mano, Miguel ; Maurer-Stroh, Sebastian; Fantuz, Marco; Zannini, Alessandro; Bicciato, Silvio; Sorrentino, Giovanni; Del Sal, GianninoarticleopenAccess
1823-Oct-2018Oncolysis with DTT-205 and DTT-304 generates immunological memory in cured animalsZhou, Heng; Mondragón, Laura; Xie, Wei; Mauseth, Brynjar; Leduc, Marion; Sauvat, Allan; Silva, Lígia C. Gomes da ; Forveille, Sabrina; Iribarren, Kristina; Souquere, Sylvie; Bezu, Lucillia; Liu, Peng; Zhao, Liwei; Zitvogel, Laurence; Sveinbjørnsson, Baldur; Eksteen, J Johannes; Rekdal, Øystein; Kepp, Oliver; Kroemer, GuidoarticleopenAccess
199-Apr-2019microRNA-155 inhibition restores Fibroblast Growth Factor 7 expression in diabetic skin and decreases wound inflammationMoura, João ; Sørensen, Anja; Leal, Ermelindo ; Svendsen, Rikke; Carvalho, Lina ; Willemoes, Rie Juul; Jørgensen, Per Trolle; Jenssen, Håvard; Wengel, Jesper; Dalgaard, Louise Torp; Carvalho, Eugenia articleopenAccess
2013-Apr-2021A selective p53 activator and anticancer agent to improve colorectal cancer therapyRamos, Helena; Soares, Maria I. L. ; Silva, Joana; Raimundo, Liliana; Calheiros, Juliana; Gomes, Célia ; Reis, Flávio ; Monteiro, Filipe A; Nunes, Cláudia; Reis, Salette ; Bosco, Bartolomeo; Piazza, Silvano; Domingues, Lucília; Chlapek, Petr; Vlcek, Petr; Fabian, Pavel; Rajado, Ana Teresa ; Carvalho, A. T. P. ; Veselska, Renata; Inga, Alberto; Pinho e Melo, Teresa M. V. D. ; Saraiva, LucíliaarticleembargoedAccess
215-Oct-2021Impact of the Pd2Spm (Spermine) Complex on the Metabolism of Triple-Negative Breast Cancer Tumors of a Xenograft Mouse ModelCarneiro, Tatiana J. ; Araújo, Rita ; Vojtek, Martin; Gonçalves-Monteiro, Salomé; Batista de Carvalho, Ana L. M. ; Marques, Maria Paula M. ; Diniz, Carmen ; Gil, Ana M.articleopenAccess
222-Jun-2021Cell surface Nucleolin represents a novel cellular target for neuroblastoma therapyBrignole, Chiara; Bensa, Veronica; Fonseca, Nuno A. ; Del Zotto, Genny; Bruno, Silvia; Cruz, Ana F. ; Malaguti, Fabiana; Carlini, Barbara; Morandi, Fabio; Calarco, Enzo; Perri, Patrizia; Moura, Vera ; Emionite, Laura; Cilli, Michele; De Leonardis, Francesco; Tondo, Annalisa; Amoroso, Loredana; Conte, Massimo; Garaventa, Alberto; Sementa, Angela R.; Corrias, Maria V.; Ponzoni, Mirco; Moreira, João N. ; Pastorino, FabioarticleopenAccess
2324-Mar-2021Neuronal cell-based high-throughput screen for enhancers of mitochondrial function reveals luteolin as a modulator of mitochondria-endoplasmic reticulum couplingNaia, Luana Carvalho ; Pinho, Catarina M.; Dentoni, Giacomo; Liu, Jianping; Leal, Nuno Santos; Ferreira, Duarte M. S.; Schreiner, Bernadette; Filadi, Riccardo; Fão, Lígia ; Connolly, Niamh M. C.; Forsell, Pontus; Nordvall, Gunnar; Shimozawa, Makoto; Greotti, Elisa; Basso, Emy; Theurey, Pierre; Gioran, Anna; Joselin, Alvin; Arsenian-Henriksson, Marie; Nilsson, Per; Rego, A. Cristina ; Ruas, Jorge L.; Park, David; Bano, Daniele; Pizzo, Paola; Prehn, Jochen H. M.; Ankarcrona, MariaarticleopenAccess
242020Anti-inflammatory potential of Portuguese thermal watersSilva, A. ; Oliveira, A. S.; Vaz, C. V.; Correia, S.; Ferreira, R. ; Breitenfeld, L.; Martinez-de-Oliveira, J.; Palmeira-de-Oliveira, R.; Pereira, C. M. F. ; Palmeira-de-Oliveira, A.; Cruz, M. T. articleopenAccess
252020PINK1/PARKIN signalling in neurodegeneration and neuroinflammationQuinn, Peter M. J.; Moreira, Paula I. ; Ambrósio, António Francisco ; Alves, C. Henrique articleopenAccess
2614-Oct-2020The Coffee-Acrylamide Apparent Paradox: An Example of Why the Health Impact of a Specific Compound in a Complex Mixture Should Not Be Evaluated in IsolationNehlig, Astrid; Cunha, Rodrigo A. articleopenAccess
2713-Apr-2021A selective p53 activator and anticancer agent to improve colorectal cancer therapyRamos, Helena; Soares, Maria I. L. ; Silva, Joana; Raimundo, Liliana; Calheiros, Juliana; Gomes, Célia ; Reis, Flávio ; Monteiro, Filipe A.; Nunes, Cláudia; Reis, Salette ; Bosco, Bartolomeo; Piazza, Silvano; Domingues, Lucília; Chlapek, Petr; Vlcek, Petr; Fabian, Pavel; Rajado, Ana Teresa; Carvalho, A. T. P. ; Veselska, Renata; Inga, Alberto; Melo, Teresa M. V. D. Pinho e ; Saraiva, LucíliaarticleopenAccess
28Jan-2020Stimulation of cell invasion by the Golgi Ion Channel GAAP/TMBIM4 via an H2O2-Dependent MechanismAlmeida, Nuno; Carrara, Guia; Palmeira, Carlos M. ; Fernandes, Ana S.; Parsons, Maddy; Smith, Geoffrey L.; Saraiva, Nuno articleopenAccess
2927-Mar-2018Memantine loaded PLGA PEGylated nanoparticles for Alzheimer's disease: in vitro and in vivo characterizationSánchez-López, Elena ; Ettcheto, Miren; Egea, Maria Antonia; Espina, Marta; Cano, Amanda ; Calpena, Ana Cristina; Camins, Antoni; Carmona, Nuria; Silva, Amelia M.; Souto, Eliana B. ; García, Maria LuisaarticleopenAccess
3012-Jun-2018Dual Therapy with Liraglutide and Ghrelin Promotes Brain and Peripheral Energy Metabolism in the R6/2 Mouse Model of Huntington's DiseaseDuarte, Ana I. ; Sjögren, Marie; Santos, Maria S. ; Oliveira, Catarina R. ; Moreira, Paula I. ; Björkqvist, MariaarticleopenAccess
315-Dec-2017Control of Huntington's Disease-Associated Phenotypes by the Striatum-Enriched Transcription Factor Foxp2Hachigian, Lea J.; Carmona, Vitor ; Fenster, Robert J.; Kulicke, Ruth; Heilbut, Adrian; Sittler, Annie; Almeida, Luís Pereira de ; Mesirov, Jill P.; Gao, Fan; Kolaczyk, Eric D.; Heiman, MyriamarticleopenAccess
321-Jul-2017Id genes are essential for early heart formationCunningham, Thomas J.; Yu, Michael S.; McKeithan, Wesley L.; Spiering, Sean; Carrette, Florent; Huang, Chun-Teng; Bushway, Paul J.; Tierney, Matthew; Albini, Sonia; Giacca, Mauro; Mano, Miguel ; Puri, Pier Lorenzo; Sacco, Alessandra; Ruiz-Lozano, Pilar; Riou, Jean-Francois; Umbhauer, Muriel; Duester, Gregg; Mercola, Mark; Colas, Alexandre R.articleopenAccess
332-Mar-2017Valorization of Lipids from Gracilaria sp. through Lipidomics and Decoding of Antiproliferative and Anti-Inflammatory ActivityCosta, Elisabete da; Melo, Tânia; Moreira, Ana S. P.; Bernardo, Carina; Helguero, Luisa; Ferreira, Isabel ; Cruz, Maria Teresa ; Rego, Andreia M.; Domingues, Pedro ; Calado, Ricardo ; Abreu, Maria H.; Domingues, Maria RosárioarticleopenAccess
34Jun-2017DIMP53-1: a novel small-molecule dual inhibitor of p53-MDM2/X interactions with multifunctional p53-dependent anticancer propertiesSoares, Joana; Espadinha, Margarida; Raimundo, Liliana; Ramos, Helena; Gomes, Ana Sara; Gomes, Sara; Loureiro, Joana B.; Inga, Alberto; Reis, Flávio ; Gomes, Célia ; Santos, Maria M. M.; Saraiva, LucíliaarticleopenAccess
3511-May-2017Prolonged intracellular accumulation of light-inducible nanoparticles in leukemia cells allows their remote activationBoto, Carlos ; Quartin, Emanuel ; Cai, Yijun; Martín-Lorenzo, Alberto; Cenador, María Begoña García; Pinto, Sandra ; Gupta, Rajeev; Enver, Tariq; Sánchez-García, Isidro; Hong, Dengli; Neves, Ricardo Pires das ; Ferreira, Lino articleopenAccess
3619-Jan-2017Glucocorticoid receptor signalling activates YAP in breast cancerSorrentino, Giovanni; Ruggeri, Naomi; Zannini, Alessandro; Ingallina, Eleonora; Bertolio, Rebecca; Marotta, Carolina; Neri, Carmelo; Cappuzzello, Elisa; Forcato, Mattia; Rosato, Antonio; Mano, Miguel ; Bicciato, Silvio; Del Sal, GianninoarticleopenAccess
37Oct-2017Transcription factor NRF2 controls the fate of neural stem cells in the subgranular zone of the hippocampusRobledinos-Antón, Natalia; Rojo, Ana I; Ferreiro, Elisabete ; Núñez, Ángel; Krause, Karl-Heinz; Jaquet, Vincent; Cuadrado, AntonioarticleopenAccess
3825-Aug-2017The Parkinson's disease-associated GPR37 receptor interacts with striatal adenosine A2A receptor controlling its cell surface expression and function in vivoMorató, Xavier; Luján, Rafael; López-Cano, Marc; Gandía, Jorge; Stagljar, Igor; Watanabe, Masahiko; Cunha, Rodrigo A. ; Fernández-Dueñas, Víctor; Ciruela, Francisco articleopenAccess
3924-Oct-2017Ghrelin rescues skeletal muscle catabolic profile in the R6/2 mouse model of Huntington's diseaseSjögren, Marie; Duarte, Ana I. ; McCourt, Andrew C.; Shcherbina, Liliya; Wierup, Nils; Björkqvist, MariaarticleopenAccess
4021-Oct-2016Natural killer cell-based adoptive immunotherapy eradicates and drives differentiation of chemoresistant bladder cancer stem-like cellsFerreira-Teixeira, Margarida ; Paiva-Oliveira, Daniela ; Parada, Belmiro ; Alves, Vera ; Sousa, Vítor ; Chijioke, Obinna; Münz, Christian; Reis, Flávio ; Rodrigues-Santos, Paulo ; Gomes, Célia articleopenAccess
4117-Jun-2016Early synaptic deficits in the APP/PS1 mouse model of Alzheimer's disease involve neuronal adenosine A2A receptorsSilva, Sílvia Viana da ; Haberl, Matthias Georg; Zhang, Pei; Bethge, Philipp; Lemos, Cristina ; Gonçalves, Nélio ; Gorlewicz, Adam; Malezieux, Meryl; Gonçalves, Francisco Q. ; Grosjean, Noëlle; Blanchet, Christophe; Frick, Andreas; Nägerl, U Valentin; Cunha, Rodrigo A. ; Mulle, Christophe articleopenAccess
4226-Jan-2016Reactivation of wild-type and mutant p53 by tryptophanolderived oxazoloisoindolinone SLMP53-1, a novel anticancer small-moleculeSoares, Joana; Raimundo, Liliana; Pereira, Nuno A. L.; Monteiro, Ângelo; Gomes, Sara; Bessa, Cláudia; Pereira, Clara; Queiroz, Glória; Bisio, Alessandra; Fernandes, João ; Gomes, Célia ; Reis, Flávio ; Gonçalves, Jorge; Inga, Alberto; Santos, Maria M. M.; Saraiva, LucíliaarticleopenAccess
4321-Jul-2015Reduced α-MSH Underlies Hypothalamic ER-Stress-Induced Hepatic GluconeogenesisSchneeberger, Marc; Gómez-Valadés, Alicia G.; Altirriba, Jordi; Sebastián, David; Ramírez, Sara; Garcia, Ainhoa; Esteban, Yaiza; Drougard, Anne; Ferrés-Coy, Albert; Bortolozzi, Analía; Garcia-Roves, Pablo M.; Jones, John G. ; Manadas, Bruno ; Zorzano, Antonio; Gomis, Ramon; Claret, MarcarticleopenAccess
4412-Feb-2015Brain ischemia downregulates the neuroprotective GDNF-Ret signaling by a calpain-dependent mechanism in cultured hippocampal neuronsCurcio, M.; Salazar, I. L. ; Inácio, A. R.; Duarte, E. P. ; Canzoniero, L. M. T.; Duarte, C. B. articleopenAccess
452015Limited Effect of Chronic Valproic Acid Treatment in a Mouse Model of Machado-Joseph DiseaseEsteves, Sofia; Duarte-Silva, Sara; Naia, Luana ; Neves-Carvalho, Andreia; Teixeira-Castro, Andreia ; Rego, Ana Cristina ; Silva-Fernandes, Anabela; Maciel, Patrícia articleopenAccess
4622-Feb-2014Intracellular coexpression of CXC- and CC- chemokine receptors and their ligands in human melanoma cell lines and dynamic variations after xenotransplantationPinto, Sandra ; Martínez-Romero, Alicia; O'Connor, José-Enrique; Gil-Benso, Rosario; San-Miguel, Teresa; Terrádez, Liria; Monteagudo, Carlos; Callaghan, Robert CarticleopenAccess
472018A nanoformulation for the preferential accumulation in adult neurogenic nichesPraça, Catarina ; Rai, Akhilesh ; Santos, Tiago ; Cristovão, Ana C.; Pinho, Sonia L.; Cecchelli, Romeo; Dehouck, Marie-Pierre ; Bernardino, Liliana Inácio ; Ferreira, Lino S. articleopenAccess
482013Essential oil of common sage (Salvia officinalis L.) from Jordan: assessment of safety in mammalian cells and its antifungal and anti-inflammatory potentialAbu-Darwish, M. S.; Cabral, C. ; Ferreira, I. V. ; Gonçalves, M. J. ; Cavaleiro, C. ; Cruz, M. T. ; Al-bdour, T. H.; Salgueiro, L. articleopenAccess
492013Silencing mutant ataxin-3 rescues motor deficits and neuropathology in Machado-Joseph disease transgenic miceNóbrega, Clévio ; Nascimento-Ferreira, Isabel ; Onofre, Isabel ; Albuquerque, David ; Hirai, Hirokazu; Déglon, Nicole ; Almeida, Luís Pereira de articleopenAccess
502013Boron nitride nanotube-mediated stimulation of cell co-culture on micro-engineered hydrogelsRicotti, Leonardo; Fujie, Toshinori; Vazão, Helena ; Ciofani, Gianni; Marotta, Roberto; Brescia, Rosaria; Filippeschi, Carlo; Corradini, Irene; Matteoli, Michela; Mattoli, Virgilio; Ferreira, Lino ; Menciassi, AriannaarticleopenAccess
Results 1-50 of 73 (Search time: 0.415 seconds).