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Issue DateTitleAuthor(s)TypeAccess
121-Oct-2020Calcium Modulation, Anti-Oxidant and Anti-Inflammatory Effect of Skin Allergens Targeting the Nrf2 Signaling Pathway in Alzheimer's Disease Cellular ModelsSilva, Ana ; Pereira, Marta ; Carrascal, Mylène A. ; Brites, Gonçalo; Neves, Bruno; Moreira, Patrícia ; Resende, Rosa ; Silva, Maria Manuel ; Santos, Armanda E. ; Pereira, Cláudia ; Cruz, Maria Teresa articleopenAccess
22022Differences in Immune-Related Genes Underlie Temporal and Regional Pathological Progression in 3xTg-AD MiceFernandes, Adelaide; Caldeira, Cláudia; Cunha, Carolina; Ferreiro, Elisabete ; Vaz, Ana Rita; Brites, Dora articleopenAccess
38-Feb-2021Neuropeptide Y (NPY) intranasal delivery alleviates Machado-Joseph diseaseDuarte-Neves, Joana ; Cavadas, Cláudia ; Almeida, Luís Pereira de articleopenAccess
418-May-2021Neuromodulation and neuroprotective effects of chlorogenic acids in excitatory synapses of mouse hippocampal slicesFernandes, Mara Yone D.; Dobrachinski, Fernando; Silva, Henrique B. ; Lopes, João Pedro ; Gonçalves, Francisco Q. ; Soares, Felix A A; Porciúncula, Lisiane O. ; Andrade, Geanne M; Cunha, Rodrigo A. ; Tomé, Ângelo R. articleopenAccess
5Aug-2019Regulation of PKCβ levels and autophagy by PML is essential for high-glucose-dependent mesenchymal stem cell adipogenesisMorganti, Claudia; Missiroli, Sonia; Lebiedzinska-Arciszewska, Magdalena; Ferroni, Letizia; Morganti, Lucia; Perrone, Mariasole; Ramaccini, Daniela; Occhionorelli, Savino; Zavan, Barbara; Wieckowski, Mariusz R. ; Giorgi, CarlottaarticleembargoedAccess
62016Highly active ozonides selected against drug resistant malariaLobo, Lis ; Sousa, Bruno de ; Cabral, Lília ; Cristiano, Maria L. S. ; Nogueira, Fátima articleopenAccess
72013Therapeutic Potential of Caspofungin Combined with Trimethoprim-Sulfamethoxazole for Pneumocystis Pneumonia: A Pilot Study in MiceLobo, Maria Luísa ; Esteves, Francisco ; Sousa, Bruno de ; Cardoso, Fernando ; Cushion, Melanie T. ; Antunes, Francisco ; Matos, Olga articleopenAccess
813-Nov-2019Retinal thinning of inner sub-layers is associated with cortical atrophy in a mouse model of Alzheimer's disease: a longitudinal multimodal in vivo studyChiquita, Samuel; Campos, Elisa J. ; Castelhano, João ; Ribeiro, Mário ; Sereno, José ; Moreira, Paula I. ; Castelo-Branco, Miguel ; Ambrósio, António Francisco articleopenAccess
92019Establishing a Link between Endothelial Cell Metabolism and Vascular Behaviour in a Type 1 Diabetes Mouse ModelSilva, Carolina; Sampaio-Pinto, Vasco; Andrade, Sara ; Rodrigues, Ilda; Costa, Raquel; Guerreiro, Susana; Carvalho, Eugenia ; Pinto-do-Ó, Perpétua; Nascimento, Diana S; Soares, RaquelarticleopenAccess
102020Adenosine A2A receptors format long-term depression and memory strategies in a mouse model of Angelman syndromeMoreira-de-Sá, Ana ; Gonçalves, Francisco Q. ; Lopes, João P. ; Silva, Henrique B. ; Tomé, Ângelo R. ; Cunha, Rodrigo A. ; Canas, Paula articleopenAccess
112018Reactive Oxygen Species Deficiency Due to Ncf1-Mutation Leads to Development of Adenocarcinoma and Metabolomic and Lipidomic Remodeling in a New Mouse Model of Dextran Sulfate Sodium-Induced ColitisCarvalho, Lina ; Gomes, Joana R. M. ; Tavares, Ludgero C. ; Xavier, Ana R.; Klika, Karel D.; Holmdahl, Rikard; Carvalho, Rui A. ; Carneiro, Maria Margarida Souto articleopenAccess
125-Jan-2021Intermittent Hypoxic Conditioning Rescues Cognition and Mitochondrial Bioenergetic Profile in the Triple Transgenic Mouse Model of Alzheimer's DiseaseCorreia, Sónia C. ; Machado, Nuno J. ; Alves, Marco G; Oliveira, Pedro F. ; Moreira, Paula I. articleopenAccess
139-Apr-2020Trehalose alleviates the phenotype of Machado-Joseph disease mouse modelsSantana, Magda M. ; Paixão, Susana ; Cunha-Santos, Janete; Silva, Teresa Pereira ; Trevino-Garcia, Allyson; Gaspar, Laetitia da Silva ; Nóbrega, Clévio ; Nobre, Rui J. ; Cavadas, Cláudia ; Greif, Hagar; Almeida, Luís Pereira de articleopenAccess
142018MicroRNA-124-loaded nanoparticles increase survival and neuronal differentiation of neural stem cells in vitro but do not contribute to stroke outcome in vivoSaraiva, Cláudia; Talhada, Daniela; Rai, Akhilesh ; Ferreira, Raquel; Ferreira, Lino ; Bernardino, Liliana ; Ruscher, Karsten articleopenAccess
1512-Jun-2018Dual Therapy with Liraglutide and Ghrelin Promotes Brain and Peripheral Energy Metabolism in the R6/2 Mouse Model of Huntington's DiseaseDuarte, Ana I. ; Sjögren, Marie; Santos, Maria S. ; Oliveira, Catarina R. ; Moreira, Paula I. ; Björkqvist, MariaarticleopenAccess
165-Dec-2017Control of Huntington's Disease-Associated Phenotypes by the Striatum-Enriched Transcription Factor Foxp2Hachigian, Lea J.; Carmona, Vitor ; Fenster, Robert J.; Kulicke, Ruth; Heilbut, Adrian; Sittler, Annie; Almeida, Luís Pereira de ; Mesirov, Jill P.; Gao, Fan; Kolaczyk, Eric D.; Heiman, MyriamarticleopenAccess
172017Testing the excitation/inhibition imbalance hypothesis in a mouse model of the autism spectrum disorder: in vivo neurospectroscopy and molecular evidence for regional phenotypesGonçalves, Joana ; Violante, Inês R. ; Sereno, José ; Leitão, Ricardo A. ; Cai, Ying; Abrunhosa, Antero ; Silva, Ana Paula ; Silva, Alcino J.; Castelo-Branco, Miguel articleopenAccess
1825-Aug-2017The Parkinson's disease-associated GPR37 receptor interacts with striatal adenosine A2A receptor controlling its cell surface expression and function in vivoMorató, Xavier; Luján, Rafael; López-Cano, Marc; Gandía, Jorge; Stagljar, Igor; Watanabe, Masahiko; Cunha, Rodrigo A. ; Fernández-Dueñas, Víctor; Ciruela, Francisco articleopenAccess
1924-Oct-2017Ghrelin rescues skeletal muscle catabolic profile in the R6/2 mouse model of Huntington's diseaseSjögren, Marie; Duarte, Ana I. ; McCourt, Andrew C.; Shcherbina, Liliya; Wierup, Nils; Björkqvist, MariaarticleopenAccess
2017-Jun-2016Early synaptic deficits in the APP/PS1 mouse model of Alzheimer's disease involve neuronal adenosine A2A receptorsSilva, Sílvia Viana da ; Haberl, Matthias Georg; Zhang, Pei; Bethge, Philipp; Lemos, Cristina ; Gonçalves, Nélio ; Gorlewicz, Adam; Malezieux, Meryl; Gonçalves, Francisco Q. ; Grosjean, Noëlle; Blanchet, Christophe; Frick, Andreas; Nägerl, U Valentin; Cunha, Rodrigo A. ; Mulle, Christophe articleopenAccess
212016Inoculated Cell Density as a Determinant Factor of the Growth Dynamics and Metastatic Efficiency of a Breast Cancer Murine ModelGregório, Ana C. ; Fonseca, Nuno A. ; Moura, Vera ; Lacerda, Manuela ; Figueiredo, Paulo; Simões, Sérgio ; Dias, Sérgio; Moreira, João Nuno articleopenAccess
222015Nitric Oxide Regulates Neurogenesis in the Hippocampus following SeizuresCarreira, Bruno P. ; Santos, Daniela F; Santos, Ana I. ; Carvalho, Caetana M. ; Araújo, InêsarticleopenAccess
232015Limited Effect of Chronic Valproic Acid Treatment in a Mouse Model of Machado-Joseph DiseaseEsteves, Sofia; Duarte-Silva, Sara; Naia, Luana ; Neves-Carvalho, Andreia; Teixeira-Castro, Andreia ; Rego, Ana Cristina ; Silva-Fernandes, Anabela; Maciel, Patrícia articleopenAccess
2422-Feb-2014Intracellular coexpression of CXC- and CC- chemokine receptors and their ligands in human melanoma cell lines and dynamic variations after xenotransplantationPinto, Sandra ; Martínez-Romero, Alicia; O'Connor, José-Enrique; Gil-Benso, Rosario; San-Miguel, Teresa; Terrádez, Liria; Monteagudo, Carlos; Callaghan, Robert CarticleopenAccess
252014Behavioral phenotyping of Parkin-deficient mice: looking for early preclinical features of Parkinson's diseaseRial, Daniel ; Castro, Adalberto A.; Machado, Nuno J. ; Garção, Pedro ; Gonçalves, Francisco Q. ; Silva, Henrique B. ; Tomé, Ângelo R. ; Köfalvi, Attila ; Corti, Olga; Raisman-Vozari, Rita; Cunha, Rodrigo A. ; Prediger, Rui D.articleopenAccess
262014Deficient production of reactive oxygen species leads to severe chronic DSS-induced colitis in Ncf1/p47phox-mutant miceRodrigues-Sousa, Tiago ; Ladeirinha, Ana Filipa Ferreira ; Santiago, Ana Raquel ; Carvalheiro, Helena ; Raposo, Bruno; Alarcão, Ana ; Cabrita, António ; Holmdahl, Rikard; Carvalho, Lina ; Carneiro, M. Margarida Souto articleopenAccess
272012A new strategy based on SmRho protein loaded chitosan nanoparticles as a candidate oral vaccine against schistosomiasisOliveira, Carolina R.; Rezende, Cíntia M. F.; Silva, Marina R.; Pêgo, Ana Paula; Borges, Olga ; Goes, Alfredo M.articleopenAccess
28Dec-2010Regulation of the mPTP by SIRT3-mediated deacetylation of CypD at lysine 166 suppresses age-related cardiac hypertrophyHafner, Angela V. ; Dai, Jing ; Gomes, Ana P. ; Xiao, Chun-Yang ; Palmeira, Carlos M. ; Rosenzweig, Anthony; Sinclair, David A.articleopenAccess
293-Oct-2023Mitochondrial Dysfunction and Decreased Cytochrome c in Cell and Animal Models of Machado-Joseph DiseaseAlmeida, Filipa ; Ferreira, Ildete L. ; Naia, Luana ; Marinho, Daniela ; Vilaça-Ferreira, Ana Catarina; Costa, Marta D.; Duarte-Silva, Sara; Maciel, Patrícia ; Rego, A. Cristina articleopenAccess
30May-2023Obstructive sleep apnea in a mouse model is associated with tissue-specific transcriptomic changes in circadian rhythmicity and mean 24-hour gene expressionKoritala, Bala S. C.; Lee, Yin Yeng; Gaspar, Laetitia S. ; Bhadri, Shweta S.; Su, Wen; Wu, Gang; Francey, Lauren J.; Ruben, Marc D.; Gong, Ming C.; Hogenesch, John B.; Smith, David F.articleopenAccess
319-Apr-2023Downregulation of Sirtuin 1 Does Not Account for the Impaired Long-Term Potentiation in the Prefrontal Cortex of Female APPswe/PS1dE9 Mice Modelling Alzheimer's DiseaseLopes, Cátia R. ; Silva, Joana S; Santos, Joana ; Rodrigues, Matilde S. ; Madeira, Daniela ; Oliveira, Andreia ; Moreira-de-Sá, Ana ; Lourenço, Vanessa S. ; Gonçalves, Francisco Q. ; Silva, Henrique B. ; Simões, Ana Patrícia; Rolo, Anabela P. ; Canas, Paula M. ; Tomé, Ângelo R. ; Palmeira, Carlos M. ; Lopes, João Pedro ; Cunha, Rodrigo A. ; Agostinho, Paula M. ; Ferreira, Samira G. articleopenAccess
329-Mar-2020Endophilin-A coordinates priming and fusion of neurosecretory vesicles via intersectinGowrisankaran, Sindhuja; Houy, Sébastien; Del Castillo, Johanna G Peña; Steubler, Vicky; Gelker, Monika; Kroll, Jana; Pinheiro, Paulo S. ; Schwitters, Dirk; Halbsgut, Nils; Pechstein, Arndt; van Weering, Jan R. T.; Maritzen, Tanja; Haucke, Volker; Raimundo, Nuno ; Sørensen, Jakob B.; Milosevic, Ira articleopenAccess
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