Eugenia Carvalho
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Credit Name
Eugenia Carvalho
Name
Carvalho, Eugenia
Biography
Dr. Carvalho, PI at the Center for Neuroscience and Cell Biology (CNC), University of Coimbra (UC), studies underlying cellular and molecular mechanisms that are in the origin of diabetes and complications. She has discovered that low insulin receptor substrate-1 protein levels in fat are predictors of pre-diabetes. She investigates insulin resistance and metabolic dysfunction in adipocytes in response to immunosuppressive and antipsychotic drugs She is studying the effect of functional foods in combating insulin resistance and inflammation, to protect from these chronic diseases.
Moreover, she is also evaluating wound healing and tissue regeneration in diabetes, with the goal of enhancing early diagnosis of subjects at risk for chronic complications in order to personalize treatment. She is assessing the role of microRNAs and antimicrobial peptides in animal models of diabetic wound healing and infection. Dr. Carvalho and her team are advocates of Health Literacy for the public.
She has published over 80 scientific papers (h-index=37; >4000 citations; google scholar). She has mentored: Post-Docs (>20); PhDs (10); Master/Erasmus students (>20) and she has obtained >30 travel fellowships from the European Foundation for the Study of Diabetes (EFSD) for young students. She has secured funding: Europe (H2020-MSCA-ITN-2016 TREATMENT; EFSD; Diabetes UK); NIH (NIGMS-NIH P20GM109096; Pepper Older American Independence Centers; ABI); National (INFARMED; FCT; SPD; SPT). She is a board member: European Tissue Repair Society, senior editor: J of Endocrinology; J Mol Endocrinology, and reviewer for >40 journals and funding agencies: MRC UK; Israel Sci F; FONDECYT/CONACYT; FWF Der Wissenschaftsfonds; Wellcome Trust; Diabetes UK; French ANR. https://www.ncbi.nlm.nih.gov/myncbi/1N_kjxvZYzSAP/bibliography/public/
Main research lines:
1 - Metabolism across the lifespan;
2 - Wound healing and tissue regeneration
3 - Oxidative capacity of circulating cells and tissues
Moreover, she is also evaluating wound healing and tissue regeneration in diabetes, with the goal of enhancing early diagnosis of subjects at risk for chronic complications in order to personalize treatment. She is assessing the role of microRNAs and antimicrobial peptides in animal models of diabetic wound healing and infection. Dr. Carvalho and her team are advocates of Health Literacy for the public.
She has published over 80 scientific papers (h-index=37; >4000 citations; google scholar). She has mentored: Post-Docs (>20); PhDs (10); Master/Erasmus students (>20) and she has obtained >30 travel fellowships from the European Foundation for the Study of Diabetes (EFSD) for young students. She has secured funding: Europe (H2020-MSCA-ITN-2016 TREATMENT; EFSD; Diabetes UK); NIH (NIGMS-NIH P20GM109096; Pepper Older American Independence Centers; ABI); National (INFARMED; FCT; SPD; SPT). She is a board member: European Tissue Repair Society, senior editor: J of Endocrinology; J Mol Endocrinology, and reviewer for >40 journals and funding agencies: MRC UK; Israel Sci F; FONDECYT/CONACYT; FWF Der Wissenschaftsfonds; Wellcome Trust; Diabetes UK; French ANR. https://www.ncbi.nlm.nih.gov/myncbi/1N_kjxvZYzSAP/bibliography/public/
Main research lines:
1 - Metabolism across the lifespan;
2 - Wound healing and tissue regeneration
3 - Oxidative capacity of circulating cells and tissues
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Publications
(All)
Results 1-25 of 25 (Search time: 0.02 seconds).
| Issue Date | Title | Author(s) | Type | Access | |
|---|---|---|---|---|---|
| 1 | 2023 | Are Dietary Sugars Potent Adipose Tissue and Immune Cell Modulators? | Barbosa, Pedro ; Carvalho, Eugenia | article | openAccess |
| 2 | 17-Dec-2021 | Bioactive Antimicrobial Peptides as Therapeutic Agents for Infected Diabetic Foot Ulcers | Da Silva, Jessica; Leal, Ermelindo C. ; Carvalho, Eugenia | article | openAccess |
| 3 | 2023 | Bioactive Ingredients in Traditional Fermented Food Condiments: Emerging Products for Prevention and Treatment of Obesity and Type 2 Diabetes | Laya, Alphonse ; Wangso, Honoré; Fernandes, Iva; Djakba, Raphaël; Oliveira, Joana; Carvalho, Eugenia | article | openAccess |
| 4 | 1-Jan-2023 | Circulating microRNA levels differ in the early stages of insulin resistance in prepubertal children with obesity | Santos, Diana ; Porter-Gill, Patricia; Goode, Grace; Delhey, Leanna; Sørensen, Anja Elaine; Rose, Shannon; Børsheim, Elisabet; Dalgaard, Louise Torp; Carvalho, Eugenia | article | openAccess |
| 5 | 7-Mar-2013 | Early cardiac changes in a rat model of prediabetes: brain natriuretic peptide overexpression seems to be the best marker | Nunes, Sara ; Soares, Edna ; Fernandes, João ; Viana, Sofia D. ; Carvalho, Eugenia ; Pereira, Frederico C. ; Reis, Flávio | article | openAccess |
| 6 | 2019 | Establishing a Link between Endothelial Cell Metabolism and Vascular Behaviour in a Type 1 Diabetes Mouse Model | Silva, Carolina; Sampaio-Pinto, Vasco; Andrade, Sara ; Rodrigues, Ilda; Costa, Raquel; Guerreiro, Susana; Carvalho, Eugenia ; Pinto-do-Ó, Perpétua; Nascimento, Diana S; Soares, Raquel | article | openAccess |
| 7 | 21-Jun-2017 | Glucose and Lipid Dysmetabolism in a Rat Model of Prediabetes Induced by a High-Sucrose Diet | Burgeiro, Ana ; Cerqueira, Manuela G. ; Varela-Rodríguez, Bárbara M; Nunes, Sara ; Neto, Paula; Pereira, Frederico C. ; Reis, Flávio ; Carvalho, Eugenia | article | openAccess |
| 8 | 25-Feb-2023 | Green Antimicrobials as Therapeutic Agents for Diabetic Foot Ulcers | Teixeira, Inês D. ; Carvalho, Eugenia ; Leal, Ermelindo C. | article | openAccess |
| 9 | 12-Mar-2021 | Improved diabetic wound healing by LFcinB is associated with relevant changes in the skin immune response and microbiota | Mouritzen, Michelle V.; Petkovic, Marija ; Qvist, Katrine; Poulsen, Steen S.; Alarico, Susana ; Leal, Ermelindo C. ; Dalgaard, Louise T.; Empadinhas, Nuno ; Carvalho, Eugenia ; Jenssen, Håvard | article | openAccess |
| 10 | 8-Jun-2023 | Innovative Functional Biomaterials as Therapeutic Wound Dressings for Chronic Diabetic Foot Ulcers | Silva, Jéssica da ; Leal, Ermelindo C. ; Carvalho, Eugenia ; Silva, Eduardo A | article | openAccess |
| 11 | 2-Oct-2020 | Mechanistic Actions of microRNAs in Diabetic Wound Healing | Petkovic, Marija ; Sørensen, Anja Elaine; Leal, Ermelindo Carreira ; Carvalho, Eugenia ; Dalgaard, Louise Torp | article | openAccess |
| 12 | 2017 | Microbiota of Chronic Diabetic Wounds: Ecology, Impact, and Potential for Innovative Treatment Strategies | Pereira, Sónia G. ; Moura, João ; Carvalho, Eugenia ; Empadinhas, Nuno | article | openAccess |
| 13 | 9-Apr-2019 | microRNA-155 inhibition restores Fibroblast Growth Factor 7 expression in diabetic skin and decreases wound inflammation | Moura, João ; Sørensen, Anja; Leal, Ermelindo ; Svendsen, Rikke; Carvalho, Lina ; Willemoes, Rie Juul; Jørgensen, Per Trolle; Jenssen, Håvard; Wengel, Jesper; Dalgaard, Louise Torp; Carvalho, Eugenia | article | openAccess |
| 14 | 29-Sep-2020 | Multi-Omic Analysis Reveals Different Effects of Sulforaphane on the Microbiome and Metabolome in Old Compared to Young Mice | Jun, Se-Ran; Cheema, Amrita; Bose, Chhanda; Boerma, Marjan; Palade, Philip T.; Carvalho, Eugenia ; Awasthi, Sanjay; Singh, Sharda P. | article | openAccess |
| 15 | 2020 | Neonatal diet impacts liver mitochondrial bioenergetics in piglets fed formula or human milk | Carvalho, Eugenia ; Adams, Sean H; Børsheim, Elisabet; Blackburn, Michael L; Ono-Moore, Kikumi D; Cotter, Matthew; Bowlin, Anne K; Yeruva, Laxmi | article | openAccess |
| 16 | 2014 | Neurotensin decreases the proinflammatory status of human skin fibroblasts and increases epidermal growth factor expression | Silva, Lucília Pereira da ; Neves, Bruno Miguel ; Moura, Liane I. F. ; Cruz, M. Teresa Girão da ; Carvalho, Eugenia | article | openAccess |
| 17 | 2013 | Neurotensin modulates the migratory and inflammatory response of macrophages under hyperglycemic conditions | Moura, Liane I. F. ; Silva, Lucília ; Leal, Ermelindo C. ; Tellechea, Ana ; Cruz, Maria Teresa ; Carvalho, Eugenia | article | openAccess |
| 18 | 2021 | Redox Imbalance and Methylation Disturbances in Early Childhood Obesity | Barbosa, Pedro ; Melnyk, Stepan; Bennuri, Sirish C; Delhey, Leanna; Reis, Andreia ; Moura, Gabriela R; Børsheim, Elisabet; Rose, Shannon; Carvalho, Eugenia | article | openAccess |
| 19 | Nov-2017 | Skeletal Muscle Acute and Chronic Metabolic Response to Essential Amino Acid Supplementation in Hypertriglyceridemic Older Adults | Marquis, Bryce J; Hurren, Nicholas M; Carvalho, Eugenia ; Kim, Il-Young; Schutzler, Scott; Azhar, Gohar; Wolfe, Robert R; Børsheim, Elisabet | article | openAccess |
| 20 | Nov-2020 | Sulforaphane prevents age-associated cardiac and muscular dysfunction through Nrf2 signaling | Bose, Chhanda; Alves, Inês ; Singh, Preeti; Palade, Philip T.; Carvalho, Eugenia ; Børsheim, Elisabet; Jun, Se-Ran; Cheema, Amrita; Boerma, Marjan; Awasthi, Sanjay; Singh, Sharda P. | article | openAccess |
| 21 | 2015 | The Place of Dipeptidyl Peptidase-4 Inhibitors in Type 2 Diabetes Therapeutics: A "Me Too" or "the Special One" Antidiabetic Class? | Godinho, Ricardo ; Mega, Cristina ; Teixeira-Lemos, Edite ; Carvalho, Eugenia ; Teixeira, Frederico ; Fernandes, Rosa ; Reis, Flávio | article | openAccess |
| 22 | 29-Sep-2014 | The Role of MicroRNAs in Diabetic Complications-Special Emphasis on Wound Healing | Moura, João ; Børsheim, Elisabet; Carvalho, Eugenia | article | openAccess |
| 23 | 17-Feb-2022 | The Role of Nutraceutical Containing Polyphenols in Diabetes Prevention | Fernandes, Iva; Oliveira, Joana; Pinho, Aryane ; Carvalho, Eugenia | article | openAccess |
| 24 | 14-Oct-2021 | Tracing Hepatic Glycogen and Lipid Metabolism with Stable Isotope Tracers: Insight From Murine Studies | Di Nunzio, Giada | doctoralThesis | openAccess |
| 25 | 20-May-2014 | Transition from cyclosporine-induced renal dysfunction to nephrotoxicity in an in vivo rat model | Sereno, José ; Rodrigues-Santos, Paulo ; Vala, Helena; Rocha-Pereira, Petronila ; Alves, Rui; Fernandes, João; Santos-Silva, Alice; Carvalho, Eugenia ; Teixeira, Frederico ; Reis, F. | article | openAccess |