Pereira, Carlos Filipe
Claim profile
Loading...
2
0
20
0
false
Credit Name
Pereira, Carlos Filipe
Name
Pereira, Carlos Filipe
Variants
Pereira, Carlos Filipe
Unidade de I&D
Email
filipe.pereira@cnc.uc.pt
Ciência ID
Scopus Author ID
Researcher ID
Status
UC Researcher
Biography
I have long held an interest in understanding how cell identity is acquired, maintained and ultimately modified or reversed. During my PhD, I have made my first contributions to the cellular reprogramming field by establishing cell fusion and heterokaryons as a new approach to study reprogramming mechanisms towards pluripotency. Of note I implicated the essential role of Polycomb repression in reprogramming. Then, during my postdoc, I brought cellular reprogramming concepts to hematopoeisis for the first time. I identified a combination of transcription factors that induces hemogenesis and established that cellular reprogramming approaches can inform the developmental specification of hematopoietic stem cells. My independent research group has now shown that cooperative transcription factor binding mediates hemogenic induction and pioneered cell fate reprogramming approaches in immunology with induced dendritic cells. This conceptual shift opens exciting opportunities to merge cellular reprogramming and cancer immunotherapy. I am an Assistant Investigator at Coimbra University and Associate Professor at Lund University and group leader of the Cell Reprogramming in Hematopoiesis and Immunity laboratory. I am also scientific co-founder of BRT Blood Reprogramming Technologies and Asgard Therapeutics.
Loading...
3
0
20
0
false
Publications
(All)
Results 1-18 of 18 (Search time: 0.022 seconds).
| Issue Date | Title | Author(s) | Type | Access | |
|---|---|---|---|---|---|
| 1 | 2021 | Cell Fate Reprogramming in the Era of Cancer Immunotherapy | Zimmermannova, Olga; Caiado, Inês ; Ferreira, Alexandra G. ; Pereira, Carlos Filipe | article | openAccess |
| 2 | 4-Dec-2018 | Cooperative Transcription Factor Induction Mediates Hemogenic Reprogramming | Gomes, Andreia ; Kurochkin, Ilia; Chang, Betty; Daniel, Michael; Law, Kenneth; Satija, Namita; Lachmann, Alexander; Wang, Zichen; Ferreira, Lino ; Ma'ayan, Avi; Chen, Benjamin K.; Papatsenko, Dmitri; Lemischka, Ihor R; Moore, Kateri A.; Pereira, Carlos Filipe | article | openAccess |
| 3 | 21-Sep-2017 | Designing Transcription Factors for Efficient Hematopoietic Reprogramming | Alves, Rita Alexandra Silvério | masterThesis | openAccess |
| 4 | 2016 | Direct Reprogramming of Fibroblasts to Dendritic Cells for Immunotherapy | Rosa, Fábio Alexandre Fiúza | masterThesis | embargoedAccess |
| 5 | 8-Oct-2018 | Elucidating Blood Origin: From Reprogramming to Ontogeny | Gomes, Andreia Marques | doctoralThesis | embargoedAccess |
| 6 | 17-Sep-2019 | Elucidating Gata2 transcription facto role during DNA replication and epigenetic inheritance | Silva, Catarina Milheiro Soares da | masterThesis | embargoedAccess |
| 7 | 14-Aug-2023 | GATA2 mitotic bookmarking is required for definitive haematopoiesis | Silvério-Alves, Rita ; Kurochkin, Ilia; Rydström, Anna; Vazquez Echegaray, Camila; Haider, Jakob; Nicholls, Matthew; Rode, Christina; Thelaus, Louise; Lindgren, Aida Yifter; Ferreira, Alexandra G. ; Brandão, Rafael; Larsson, Jonas; de Bruijn, Marella F. T. R.; Martin-Gonzalez, Javier; Pereira, Carlos Filipe | article | openAccess |
| 8 | 10-Jun-2021 | Generating dendritic cells by direct cell reprogramming | Rosa, Fábio Alexandre Fiúza | doctoralThesis | openAccess |
| 9 | 3-Sep-2023 | High-Throughput Drug Screening Revealed That Ciclopirox Olamine Can Engender Gastric Cancer Stem-like Cells | Pádua, Diana; Figueira, Paula; Pinto, Mariana; Maia, André Filipe; Peixoto, Joana; Lima, Raquel T; Pombinho, António; Pereira, Carlos Filipe ; Almeida, Raquel ; Mesquita, Patrícia | article | openAccess |
| 10 | 2021 | HMGA1 Has Predictive Value in Response to Chemotherapy in Gastric Cancer | Pádua, Diana; Pinto, Débora Filipa; Figueira, Paula; Pereira, Carlos Filipe ; Almeida, Raquel ; Mesquita, Patrícia | article | openAccess |
| 11 | 25-Sep-2018 | Inducing Antigen Presentation in Tumor cells by Direct Reprogramming | Caiado, Inês Maria Nascimento | masterThesis | embargoedAccess |
| 12 | 3-Nov-2023 | Mechanisms Underlying the Specification of Definitive Hematopoiesis | Alves, Rita | doctoralThesis | openAccess |
| 13 | 14-Jul-2023 | Restoring tumor immunogenicity with dendritic cell reprogramming | Zimmermannova, Olga; Ferreira, Alexandra G. ; Ascic, Ervin; Velasco Santiago, Marta; Kurochkin, Ilia; Hansen, Morten; Met, Özcan; Caiado, Inês ; Shapiro, Ilja E.; Michaux, Justine; Humbert, Marion; Soto-Cabrera, Diego; Benonisson, Hreinn; Silvério-Alves, Rita ; Gomez-Jimenez, David; Bernardo, Carina; Bauden, Monika; Andersson, Roland; Höglund, Mattias; Miharada, Kenichi; Nakamura, Yukio; Hugues, Stephanie; Greiff, Lennart; Lindstedt, Malin; Rosa, Fábio F. ; Pires, Cristiana F.; Bassani-Sternberg, Michal; Svane, Inge Marie; Pereira, Carlos Filipe | article | openAccess |
| 14 | 19-Sep-2018 | The role of LSD1/CoREST during hemogenic reprogramming. | Santos, Ana Raquel Pereira | masterThesis | embargoedAccess |
| 15 | 20-Feb-2020 | A SOX2 Reporter System Identifies Gastric Cancer Stem-Like Cells Sensitive to Monensin | Pádua, Diana; Barros, Rita ; Amaral, Ana Luísa ; Mesquita, Patrícia; Freire, Ana Filipa ; Sousa, Mafalda ; Maia, André Filipe; Caiado, Inês ; Fernandes, Hugo; Pombinho, António; Pereira, Carlos Filipe ; Almeida, Raquel | article | openAccess |
| 16 | 11-Jul-2017 | Transient HES5 Activity Instructs Mesodermal Cells toward a Cardiac Fate | Freire, Ana G.; Waghray, Avinash; Soares-da-Silva, Francisca ; Resende, Tatiana P.; Lee, Dung-Fang; Pereira, Carlos Filipe ; Nascimento, Diana S.; Lemischka, Ihor R.; Pinto-do-Ó, Perpétua | article | openAccess |
| 17 | 2019 | Understanding and Modulating Immunity With Cell Reprogramming | Pires, Cristiana Ferreira ; Rosa, Fábio F. ; Kurochkin, Ilia; Pereira, Carlos Filipe | article | openAccess |
| 18 | 18-Sep-2019 | Understanding the Genetic Program of Conventional Dendritic Cells Type 2 with Direct Cell Reprogramming | Oliveira, Luís Filipe Henriques | masterThesis | embargoedAccess |