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Credit Name
Brito, Rui
 
Name
Brito, Rui M. M.
 
Variants
Brito, Rui
Brito, Rui Manuel Pontes Meireles Ferreira de
 
 
Email
brito@ci.uc.pt
 
 
Scopus Author ID
 
Status
UC Researcher
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Publications
(Todas)

Resultados 1-32 de 32.

Data de publicaçãoTítuloAutor(es)TipoAcesso
119-Abr-2022Alchemical Design of Pharmacological Chaperones with Higher Affinity for Phenylalanine HydroxylaseConde-Giménez, María; Galano-Frutos, Juan José; Galiana-Cameo, María; Mahía, Alejandro; Victor, Bruno L. ; Salillas, Sandra; Velázquez-Campoy, Adrián; Brito, Rui M. M. ; Gálvez, José Antonio; Díaz-de-Villegas, María D.; Sancho, JavierarticleopenAccess
22020An Innovative Sequence-to-Structure-Based Approach to Drug Resistance Interpretation and Prediction: The Use of Molecular Interaction Fields to Detect HIV-1 Protease Binding-Site DissimilaritiesAlves, Nuno G. ; Mata, Ana I. ; Luís, João P. ; Brito, Rui M. M. ; Simões, Carlos J. V. articleopenAccess
32016Cell Spotting: educational and motivational outcomes of cell biology citizen science project in the classroomBrito, Rui M. M. ; Carrodeguas, Jose; Serrano Sanz, Fermin; Mota, Paulo ; Brasileiro, Francisco; Andrade, Nazareno; Schäfer, Teresa; Lostal, Eduardo; Manahl, Caroline; Monteiro, Antonio; Silva, Cândida G. articleopenAccess
42012Changes in channel trafficking and protein stability caused by LQT2 mutations in the PAS domain of the HERG channelHarley, Carol A.; Jesus, Catarina S. H. ; Carvalho, Ricardo; Brito, Rui M. M. ; Morais-Cabral, João H.articleopenAccess
5Set-2010Cinética de agregação da proteína transtirretina: contribuição para a compreensão dos processos de formação de amilóideAlmeida, Zaida C. Lourenço de masterThesisopenAccess
62000Comparative calorimetric study of non-amyloidogenic and amyloidogenic variants of the homotetrameric protein transthyretinShnyrov, Valery L. ; Villar, Enrique ; Zhadan, Galina G. ; Sanchez-Ruiz, Jose M. ; Quintas, Alexandre ; Saraiva, Maria João M. ; Brito, Rui M. M. articleopenAccess
726-Fev-2022Conformational Dynamics of the Soluble and Membrane-Bound Forms of Interleukin-1 Receptor Type-1: Insights into Linker Flexibility and Domain OrientationLuís, João P. ; Mata, Ana I. ; Simões, Carlos J. V. ; Brito, Rui M. M. articleopenAccess
8Fev-2016Em busca de determinantes estruturais no reconhecimento e ligação de amilóide: β-2 microglobulina como caso de estudoFernandes, Pedro Miguel Pinto masterThesisopenAccess
92012Uma estratégia para a discriminação entre compostos activos e inactivos em experiências de rastreio virtual : COX-1 como caso de estudoCarreiras, Pedro Miguel Serrano Germano Calado masterThesisopenAccess
1027-Set-2017Estudo das alterações metabólicas post mortem no fígado por espectroscopia de RMNTomé, Ana Sofia Monteiro masterThesisopenAccess
112016Hereditary nonspherocytic hemolytic anemia caused by red cell glucose-6-phosphate isomerase (GPI) deficiency in two Portuguese patients: Clinical features and molecular studyManco, Licínio ; Bento, Celeste ; Victor, Bruno L. ; Pereira, Janet ; Relvas, Luís ; Brito, Rui M. ; Seabra, Carlos ; Maia, Tabita M. ; Ribeiro, M. Letícia articleopenAccess
12Set-2015Identification and characterization of small molecule interactions with transthyretin amyloid fibersFerreira, Elisabete Priscila Pinto masterThesisopenAccess
1331-Jan-2014Kinetics and Energetics of Fundamental Events in Peptide and Protein (Un)FoldingJesus, Catarina Sofia Henriques de doctoralThesisembargoedAccess
1414-Nov-2020Ligand-Targeted Delivery of Photosensitizers for Cancer TreatmentGierlich, Piotr ; Mata, Ana I. ; Donohoe, Claire ; Brito, Rui M. M. ; Senge, Mathias O. ; Silva, Lígia C. Gomes da articleopenAccess
1531-Ago-2016A New Folding Kinetic Mechanism for Human Transthyretin and the Influence of the Amyloidogenic V30M MutationJesus, Catarina S. H. ; Almeida, Zaida L. ; Vaz, Daniela C. ; Faria, Tiago Q. ; Brito, Rui M. M. articleopenAccess
163-Dez-2020Oligomerization Profile of Human Transthyretin Variants with Distinct AmyloidogenicityFrangolho, Ana; Correia, Bruno E.; Vaz, Daniela C. ; Almeida, Zaida L. ; Brito, Rui M. M. articleopenAccess
1726-Set-2019OSA and TransthyretinSantos, Alexander Michael RibeiromasterThesisembargoedAccess
1825-Set-2019O papel dos halogénios no desenho de fármacos. O caso da ligação de pequenos ligantes à Transtirretina.Caniceiro, Ana Beatriz Ramos masterThesisopenAccess
1915-Nov-2010Protein conformational plasticity and aggregation : transthyretin and δ-toxin as two case studiesFerreira, Nuno Ricardo Santos Loureiro da Silva doctoralThesisopenAccess
2030-Dez-2021Searching for the Best Transthyretin Aggregation Protocol to Study Amyloid Fibril DisruptionFerreira, Elisabete ; Almeida, Zaida L. ; Cruz, Pedro F. ; Sousa, Marta Silva e ; Veríssimo, Paula ; Brito, Rui M. M. articleopenAccess
212013A serpin released by an entomopathogen impairs clot formation in insect defense systemToubarro, Duarte; Avila, Mónica M.; Hao, Youjin; Balasubramanian, Natesan; Jing, Yingjun; Montiel, Rafael ; Faria, Tiago Q. ; Brito, Rui M. ; Simões, Nelson articleopenAccess
2229-Jun-1999Solution Structures of the C-Terminal Domain of Cardiac Troponin C Free and Bound to the N-Terminal Domain of Cardiac Troponin IGasmi-Seabrook, Geneviève M. C. ; Howarth, Jack W. ; Finley, Natosha ; Abusamhadneh, Ekram ; Gaponenko, Vadim ; Brito, Rui M. M. ; Solaro, R. John ; Rosevear, Paul R. articleopenAccess
236-Mar-2020Structure and Aggregation Mechanisms in AmyloidsAlmeida, Zaida L. ; Brito, Rui M. M. articleopenAccess
241-Jun-2022Targeting Neuroinflammation: from target validation to rational design of selective modulatorsLuís, João Pedro dos ReisdoctoralThesisopenAccess
25Fev-2013The apoptogenic toxin AIP56 is a metalloprotease A-B toxin that cleaves NF-κb P65Silva, Daniela S.; Pereira, Liliana M. G.; Moreira, Ana R.; Ferreira-da-Silva, Frederico; Brito, Rui M. ; Faria, Tiago Q. ; Zornetta, Irene; Montecucco, Cesare; Oliveira, Pedro; Azevedo, Jorge E.; Pereira, Pedro J. B.; Macedo-Ribeiro, Sandra ; do Vale, Ana; dos Santos, Nuno M. S.articleopenAccess
2622-Fev-2020The Central Role of Non-Structural Protein 1 (NS1) in Influenza Biology and InfectionRosário-Ferreira, Nícia ; Preto, Antonio J. ; Melo, Rita ; Moreira, Irina S. ; Brito, Rui M. M. articleopenAccess
272-Fev-2022The Therapeutic Prospects of Targeting IL-1R1 for the Modulation of Neuroinflammation in Central Nervous System DisordersLuís, João P. ; Simões, Carlos J. V. ; Brito, Rui M. M. articleopenAccess
282012The V30M Amyloidogenic Mutation Decreases the Rate of Refolding Kinetics of the Tetrameric Protein TransthyretinJesus, Catarina S. H. ; Vaz, Daniela C. ; Saraiva, Maria J. M.; Brito, Rui M. M. articleopenAccess
292005Towards Data Warehousing and Mining of Protein Unfolding Simulation DataBerrar, Daniel ; Stahl, Frederic ; Silva, Candida ; Rodrigues, J. ; Brito, Rui ; Dubitzky, Werner articleopenAccess
3011-Set-2017Towards the discovery of novel anti-Influenza agents using a reverse virtual fragment screening approachCunha, Andreia Espírito Santo masterThesisopenAccess
313-Fev-2023Unveiling New Druggable Pockets in Influenza Non-Structural Protein 1: NS1-Host Interactions as Antiviral Targets for FluCunha, Andreia E. S. ; Loureiro, Rui J. S. ; Simões, Carlos J. V. ; Brito, Rui M. M. articleopenAccess
3220-Dez-2012Virtual Screening with Sense and Sensibility in the Search of New Amyloid InhibitorsSimões, Carlos José Vieira doctoralThesisopenAccess