Please use this identifier to cite or link to this item:
https://hdl.handle.net/10316/45024
Title: | Solid-state studies and antioxidant properties of the γ-cyclodextrin·fisetin inclusion compound | Authors: | Pais, Joana M. Barroca, Maria João Marques, M. P. M. Almeida Paz, Filipe A. Braga, Susana S. |
Issue Date: | 1-Jan-2017 | Serial title, monograph or event: | Beilstein Journal of Organic Chemistry | Volume: | 13 | Abstract: | Fisetin is a natural antioxidant with a wide range of nutraceutical properties, including antidiabetic, neuroprotecting, and suppression or prevention of tumors. The present work describes the preparation of a water-soluble, solid inclusion compound of fisetin with gamma-cyclodextrin (γ-CD), a cyclic oligosaccharide approved for human consumption. A detailed physicochemical analysis of the product is carried out using elemental analysis, powder X-ray diffraction (PXRD), Raman, infrared and 13C{1H} CP-MAS NMR spectroscopies, and thermal analysis (TGA) to verify fisetin inclusion and to present a hypothetical structural arrangement for the host-guest units. The antioxidant activity of the γ-CD·fisetin inclusion compound is evaluated by the DPPH assay. | URI: | https://hdl.handle.net/10316/45024 | DOI: | 10.3762/bjoc.13.212 | Rights: | embargoedAccess |
Appears in Collections: | FCTUC Ciências da Vida - Artigos em Revistas Internacionais |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
BJOC_17.pdf | 657.56 kB | Adobe PDF | View/Open |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.