Please use this identifier to cite or link to this item: http://hdl.handle.net/10316/45024
Title: Solid-state studies and antioxidant properties of the γ-cyclodextrin·fisetin inclusion compound
Authors: Pais, Joana M 
Barroca, Maria João 
Marques, M P M 
Almeida Paz, Filipe A 
Braga, Susana S 
Issue Date: 1-Jan-2017
Serial title, monograph or event: Beilstein Journal of Organic Chemistry
Volume: 13
Abstract: Fisetin is a natural antioxidant with a wide range of nutraceutical properties, including antidiabetic, neuroprotecting, and suppression or prevention of tumors. The present work describes the preparation of a water-soluble, solid inclusion compound of fisetin with gamma-cyclodextrin (γ-CD), a cyclic oligosaccharide approved for human consumption. A detailed physicochemical analysis of the product is carried out using elemental analysis, powder X-ray diffraction (PXRD), Raman, infrared and 13C{1H} CP-MAS NMR spectroscopies, and thermal analysis (TGA) to verify fisetin inclusion and to present a hypothetical structural arrangement for the host-guest units. The antioxidant activity of the γ-CD·fisetin inclusion compound is evaluated by the DPPH assay.
URI: http://hdl.handle.net/10316/45024
DOI: 10.3762/bjoc.13.212
Rights: embargoedAccess
Appears in Collections:FCTUC Ciências da Vida - Artigos em Revistas Internacionais

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