Please use this identifier to cite or link to this item:
https://hdl.handle.net/10316/115155
Title: | Seaweeds as Nutraceutical Elements and Drugs for Diabetes Mellitus: Future Perspectives | Authors: | Cotas, João Lomartire, Silvia Pereira, Leonel Valado, Ana Marques, J. Gonçalves, Ana Marta |
Keywords: | antidiabetic agents; chemical diversity; complications; diabetes mellitus; high blood glucose levels; insulin; marine natural products; mechanisms of action; multitargeted effects; peptides; polyphenols; polysaccharides; preclinical studies; seaweeds; therapeutic potential | Issue Date: | 10-Apr-2024 | Publisher: | MDPI | Project: | info:eu-repo/grantAgreement/UIDB/04004/2020 info:eu-repo/grantAgreement/UIDB/04292/2020/PT info:eu-repo/grantAgreement/FCT/UIDP/04292/2020 LA/P/0069/2020 UIDB/50017/2020 UIDP/50017/2020 info:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/LA/P/0092/2020/PT |
Serial title, monograph or event: | Marine Drugs | Volume: | 22 | Issue: | 4 | Abstract: | Diabetes mellitus is a chronic metabolic condition marked by high blood glucose levels caused by inadequate insulin synthesis or poor insulin use. This condition affects millions of individuals worldwide and is linked to a variety of consequences, including cardiovascular disease, neuropathy, nephropathy, and retinopathy. Diabetes therapy now focuses on controlling blood glucose levels through lifestyle changes, oral medicines, and insulin injections. However, these therapies have limits and may not successfully prevent or treat diabetic problems. Several marine-derived chemicals have previously demonstrated promising findings as possible antidiabetic medicines in preclinical investigations. Peptides, polyphenols, and polysaccharides extracted from seaweeds, sponges, and other marine species are among them. As a result, marine natural products have the potential to be a rich source of innovative multitargeted medications for diabetes prevention and treatment, as well as associated complications. Future research should focus on the chemical variety of marine creatures as well as the mechanisms of action of marine-derived chemicals in order to find new antidiabetic medicines and maximize their therapeutic potential. Based on preclinical investigations, this review focuses on the next step for seaweed applications as potential multitargeted medicines for diabetes, highlighting the bioactivities of seaweeds in the prevention and treatment of this illness. | URI: | https://hdl.handle.net/10316/115155 | ISSN: | 1660-3397 | DOI: | 10.3390/md22040168 | Rights: | openAccess |
Appears in Collections: | I&D MARE - Artigos em Revistas Internacionais FCTUC Ciências da Vida - Artigos em Revistas Internacionais I&D CFE - Artigos em Revistas Internacionais |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
marinedrugs-22-00168 (1).pdf | 1.63 MB | Adobe PDF | View/Open |
Page view(s)
106
checked on Oct 16, 2024
Download(s)
33
checked on Oct 16, 2024
Google ScholarTM
Check
Altmetric
Altmetric
This item is licensed under a Creative Commons License