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Title: Antioxidant and Antidiabetic Activity of Algae
Authors: Abo-Shady, Atef Mohamed
Gheda, Saly Farouk
Ismail, Gehan Ahmed
Cotas, João 
Pereira, Leonel 
Abdel-Karim, Omnia Hamdy
Keywords: algal treatments; antihyperglycemic; antioxidant; body weight; diabetes; lipid profile
Issue Date: 7-Feb-2023
Publisher: MDPI
Project: UIDB/04292/2020 
European Regional Development Fund through the Interreg Atlantic Area Program, under the project NASPA (EAPA_451/2016) 
Serial title, monograph or event: Life
Volume: 13
Issue: 2
Abstract: Currently, algae arouse a growing interest in the pharmaceutical and cosmetic area due to the fact that they have a great diversity of bioactive compounds with the potential for pharmacological and nutraceutical applications. Due to lifestyle modifications brought on by rapid urbanization, diabetes mellitus, a metabolic illness, is the third largest cause of death globally. The hunt for an efficient natural-based antidiabetic therapy is crucial to battling diabetes and the associated consequences due to the unfavorable side effects of currently available antidiabetic medications. Finding the possible advantages of algae for the control of diabetes is crucial for the creation of natural drugs. Many of algae's metabolic processes produce bioactive secondary metabolites, which give algae their diverse chemical and biological features. Numerous studies have demonstrated the antioxidant and antidiabetic benefits of algae, mostly by blocking carbohydrate hydrolyzing enzyme activity, such as α-amylase and α-glucosidase. Additionally, bioactive components from algae can lessen diabetic symptoms in vivo. Therefore, the current review concentrates on the role of various secondary bioactive substances found naturally in algae and their potential as antioxidants and antidiabetic materials, as well as the urgent need to apply these substances in the pharmaceutical industry.
ISSN: 2075-1729
DOI: 10.3390/life13020460
Rights: openAccess
Appears in Collections:FCTUC Ciências da Vida - Artigos em Revistas Internacionais
I&D MARE - Artigos em Revistas Internacionais

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