Please use this identifier to cite or link to this item:
https://hdl.handle.net/10316/113379
Title: | Marine Macroalgae Polyphenols as Potential Neuroprotective Antioxidants in Neurodegenerative Diseases | Authors: | Lomartire, Silvia Gonçalves, Ana M. M. |
Keywords: | marine polyphenols; seaweeds; antioxidant activity; neurodegenerative diseases; neuroprotective activity | Issue Date: | 23-Apr-2023 | Publisher: | MDPI | Project: | LA/P/0069/ 2020 info:eu-repo/grantAgreement/UIDB/04292/2020 UIDP/50017/2020 UIDB/50017/2020 2021.05005.BD |
Serial title, monograph or event: | Marine Drugs | Volume: | 21 | Issue: | 5 | Abstract: | Polyphenols are beneficial natural compounds with antioxidant properties that have recently gain a lot of interest for their potential therapeutic applications. Marine polyphenols derived from marine macroalgae have been discovered to possess interesting antioxidant properties; therefore, these compounds can be included in several areas of drug development. Authors have considered the use of polyphenol extracts from seaweeds as neuroprotective antioxidants in neurodegenerative diseases. Marine polyphenols may slow the progression and limit neuronal cell loss due to their antioxidant activity; therefore, the use of these natural compounds would improve the quality of life for patients affected with neurodegenerative diseases. Marine polyphenols have distinct characteristics and potential. Among seaweeds, brown algae are the main sources of polyphenols, and present the highest antioxidant activity in comparison to red algae and green algae. The present paper collects the most recent in vitro and in vivo evidence from investigations regarding polyphenols extracted from seaweeds that exhibit neuroprotective antioxidant activity. Throughout the review, oxidative stress in neurodegeneration and the mechanism of action of marine polyphenol antioxidant activity are discussed to evidence the potential of algal polyphenols for future use in drug development to delay cell loss in patients with neurodegenerative disorders. | URI: | https://hdl.handle.net/10316/113379 | ISSN: | 1660-3397 | DOI: | 10.3390/md21050261 | Rights: | openAccess |
Appears in Collections: | FCTUC Ciências da Vida - Artigos em Revistas Internacionais I&D MARE - Artigos em Revistas Internacionais |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
Marine-Macroalgae-Polyphenols-as-Potential-Neuroprotective-Antioxidants-in-Neurodegenerative-DiseasesMarine-Drugs.pdf | 1.37 MB | Adobe PDF | View/Open |
Page view(s)
72
checked on Sep 25, 2024
Download(s)
13
checked on Sep 25, 2024
Google ScholarTM
Check
Altmetric
Altmetric
This item is licensed under a Creative Commons License