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https://hdl.handle.net/10316/112159
Title: | Overview of Caffeine Effects on Human Health and Emerging Delivery Strategies | Authors: | Saraiva, Sofia M. Jacinto, Telma A. Gonçalves, Ana C. Gaspar, Dário Silva, Luís R. |
Keywords: | caffeine; health benefits; athletic effects; dietary supplements; nanocarriers | Issue Date: | 27-Jul-2023 | Publisher: | MDPI | Project: | CENTRO- 04-3559-FSE-000162 UIDP/00709/2020 UIDB/00709/2020 PD21-00023 PRR-C05-i03-I-000143 2020.04947.BD |
Serial title, monograph or event: | Pharmaceuticals | Volume: | 16 | Issue: | 8 | Abstract: | Caffeine is a naturally occurring alkaloid found in various plants. It acts as a stimulant, antioxidant, anti-inflammatory, and even an aid in pain management, and is found in several over-the-counter medications. This naturally derived bioactive compound is the best-known ingredient in coffee and other beverages, such as tea, soft drinks, and energy drinks, and is widely consumed worldwide. Therefore, it is extremely important to research the effects of this substance on the human body. With this in mind, caffeine and its derivatives have been extensively studied to evaluate its ability to prevent diseases and exert anti-aging and neuroprotective effects. This review is intended to provide an overview of caffeine's effects on cancer and cardiovascular, immunological, inflammatory, and neurological diseases, among others. The heavily researched area of caffeine in sports will also be discussed. Finally, recent advances in the development of novel nanocarrier-based formulations, to enhance the bioavailability of caffeine and its beneficial effects will be discussed. | URI: | https://hdl.handle.net/10316/112159 | ISSN: | 1424-8247 | DOI: | 10.3390/ph16081067 | Rights: | openAccess |
Appears in Collections: | FCTUC Eng.Química - Artigos em Revistas Internacionais I&D CERES - Artigos em Revistas Internacionais |
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