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https://hdl.handle.net/10316/11197| Title: | A mathematical model for a comprehensive approach to the dynamics of human colonic aberrant crypt foci | Authors: | Figueiredo, Isabel N. Figueiredo, Pedro N. Leal, Carlos Urbano, José Miguel |
Keywords: | Aberrant crypt foci; Logistic differential equation; Apoptosis index; Proliferation index; Colorectal cancer | Issue Date: | 2008 | Publisher: | Centro de Matemática da Universidade de Coimbra | Citation: | Pré-Publicações DMUC. 08-01 (2008) | Abstract: | In this paper, we propose mathematical models for the growth dynamics of aberrant crypt foci in the human colon, as well as for some of their characteristics, namely the apoptosis and proliferation indices. The models rely on logistic type differential equations and clinical observations at different times, and can arguably be used as an auxiliary screening tool for colon cancer. We report several results using available medical data. | URI: | https://hdl.handle.net/10316/11197 | Rights: | openAccess |
| Appears in Collections: | FMUC Medicina - Vários FCTUC Matemática - Vários |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| A mathematical model for aberrant crypt foci.pdf | 2.13 MB | Adobe PDF | View/Open |
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