Please use this identifier to cite or link to this item:
https://hdl.handle.net/10316/11197
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Figueiredo, Isabel N. | - |
dc.contributor.author | Figueiredo, Pedro N. | - |
dc.contributor.author | Leal, Carlos | - |
dc.contributor.author | Urbano, José Miguel | - |
dc.date.accessioned | 2009-08-27T08:16:34Z | - |
dc.date.available | 2009-08-27T08:16:34Z | - |
dc.date.issued | 2008 | - |
dc.identifier.citation | Pré-Publicações DMUC. 08-01 (2008) | en_US |
dc.identifier.uri | https://hdl.handle.net/10316/11197 | - |
dc.description.abstract | In this paper, we propose mathematical models for the growth dynamics of aberrant crypt foci in the human colon, as well as for some of their characteristics, namely the apoptosis and proliferation indices. The models rely on logistic type differential equations and clinical observations at different times, and can arguably be used as an auxiliary screening tool for colon cancer. We report several results using available medical data. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Centro de Matemática da Universidade de Coimbra | en_US |
dc.rights | openAccess | eng |
dc.subject | Aberrant crypt foci | en_US |
dc.subject | Logistic differential equation | en_US |
dc.subject | Apoptosis index | en_US |
dc.subject | Proliferation index | en_US |
dc.subject | Colorectal cancer | en_US |
dc.title | A mathematical model for a comprehensive approach to the dynamics of human colonic aberrant crypt foci | en_US |
dc.type | preprint | en_US |
uc.controloAutoridade | Sim | - |
item.openairecristype | http://purl.org/coar/resource_type/c_816b | - |
item.openairetype | preprint | - |
item.cerifentitytype | Publications | - |
item.grantfulltext | open | - |
item.fulltext | Com Texto completo | - |
item.languageiso639-1 | en | - |
crisitem.author.researchunit | CMUC - Centre for Mathematics of the University of Coimbra | - |
crisitem.author.researchunit | CMUC - Centre for Mathematics of the University of Coimbra | - |
crisitem.author.orcid | 0000-0002-0215-8851 | - |
crisitem.author.orcid | 0000-0001-9872-6341 | - |
crisitem.author.orcid | 0000-0002-5715-2588 | - |
Appears in Collections: | FMUC Medicina - Vários FCTUC Matemática - Vários |
Files in This Item:
File | Description | Size | Format | |
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A mathematical model for aberrant crypt foci.pdf | 2.13 MB | Adobe PDF | View/Open |
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