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Title: | Progressing nanotechnology to improve targeted cancer treatment: overcoming hurdles in its clinical implementation | Authors: | Chehelgerdi, Mohammad Chehelgerdi, Matin Allela, Omer Qutaiba B Pecho, Renzon Daniel Cosme Jayasankar, Narayanan Rao, Devendra Pratap Thamaraikani, Tamilanban Vasanthan, Manimaran Viktor, Patrik Lakshmaiya, Natrayan Saadh, Mohamed J. Amajd, Ayesha Abo-Zaid, Mabrouk A Castillo-Acobo, Roxana Yolanda Ismail, Ahmed H. Amin, Ali H. Akhavan-Sigari, Reza |
Keywords: | Nanotechnology; Cancer detection; Cancer treatment; Nanoscale targeting techniques; Protein engineering; Materials science; Nanocarriers; Medicinal purposes; Human trials | Issue Date: | 9-Oct-2023 | Publisher: | Springer Nature | Project: | Deputyship for Research & Innovation, Ministry of Education in Saudi Arabia project number : IFP22UQU4331100DSR020 | Serial title, monograph or event: | Molecular Cancer | Volume: | 22 | Issue: | 1 | Abstract: | The use of nanotechnology has the potential to revolutionize the detection and treatment of cancer. Developments in protein engineering and materials science have led to the emergence of new nanoscale targeting techniques, which offer renewed hope for cancer patients. While several nanocarriers for medicinal purposes have been approved for human trials, only a few have been authorized for clinical use in targeting cancer cells. In this review, we analyze some of the authorized formulations and discuss the challenges of translating findings from the lab to the clinic. This study highlights the various nanocarriers and compounds that can be used for selective tumor targeting and the inherent difficulties in cancer therapy. Nanotechnology provides a promising platform for improving cancer detection and treatment in the future, but further research is needed to overcome the current limitations in clinical translation. | URI: | https://hdl.handle.net/10316/111222 | ISSN: | 1476-4598 | DOI: | 10.1186/s12943-023-01865-0 | Rights: | openAccess |
Appears in Collections: | FCTUC Eng.Mecânica - Artigos em Revistas Internacionais I&D CEMMPRE - Artigos em Revistas Internacionais |
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