Please use this identifier to cite or link to this item:
https://hdl.handle.net/10316/109265
Title: | Field evaluation of a push-pull system to reduce malaria transmission | Authors: | Menger, David J. Omusula, Philemon Holding, Maarten Homan, Tobias Carreira, Ana S. Vandendaele, Patrice Derycke, Jean-Luc Mweresa, Collins K. Mukabana, Wolfgang Richard van Loon, Joop J. A. Takken, Willem |
Issue Date: | 2015 | Publisher: | Public Library of Science | Serial title, monograph or event: | PLoS ONE | Volume: | 10 | Issue: | 4 | Abstract: | Malaria continues to place a disease burden on millions of people throughout the tropics, especially in sub-Saharan Africa. Although efforts to control mosquito populations and reduce human-vector contact, such as long-lasting insecticidal nets and indoor residual spraying, have led to significant decreases in malaria incidence, further progress is now threatened by the widespread development of physiological and behavioural insecticide-resistance as well as changes in the composition of vector populations. A mosquito-directed push-pull system based on the simultaneous use of attractive and repellent volatiles offers a complementary tool to existing vector-control methods. In this study, the combination of a trap baited with a five-compound attractant and a strip of net-fabric impregnated with micro-encapsulated repellent and placed in the eaves of houses, was tested in a malaria-endemic village in western Kenya. Using the repellent delta-undecalactone, mosquito house entry was reduced by more than 50%, while the traps caught high numbers of outdoor flying mosquitoes. Model simulations predict that, assuming area-wide coverage, the addition of such a push-pull system to existing prevention efforts will result in up to 20-fold reductions in the entomological inoculation rate. Reductions of such magnitude are also predicted when mosquitoes exhibit a high resistance against insecticides. We conclude that a push-pull system based on non-toxic volatiles provides an important addition to existing strategies for malaria prevention. | URI: | https://hdl.handle.net/10316/109265 | ISSN: | 1932-6203 | DOI: | 10.1371/journal.pone.0123415 | Rights: | openAccess |
Appears in Collections: | I&D CERES - Artigos em Revistas Internacionais |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
Field-evaluation-of-a-pushpull-system-to-reduce-malaria-transmissionPLoS-ONE.pdf | 4.23 MB | Adobe PDF | View/Open |
Page view(s)
82
checked on Oct 16, 2024
Download(s)
53
checked on Oct 16, 2024
Google ScholarTM
Check
Altmetric
Altmetric
This item is licensed under a Creative Commons License