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Credit Name
Santana, Isabel
 
Name
Santana, Isabel J.
 
Variants
Santana, Isabel
Santana, I.
 
 
 
Ciência ID
 
Scopus Author ID
 
Status
UC Researcher
Biography
Maria Isabel Jacinto Santana graduated in Medicine at the University of Coimbra in 1984, completed is PhD in Neurology (Alzheimer's Disease) in 1999 and is Full Professor of Neurology at the Faculty of Medicine of the University of Coimbra and co-coordinator of the Neurosciences and Mental Health Group since 2019. She is the director of the Neurology Department at the Centro Hospitalar e Universitário de Coimbra, being head of the Memory/Dementia Clinic and the Neuropsychological Unit and coordinator of the Coimbra Center at the European Alzheimers disease Consortium (EADC). Her main areas of expertise are neurodegenerative diseases in both clinical practise and translational investigation, including 20 years of experience in clinical trials and is a member of the National Ethics Committee for Clinical Investigation (CEIC) since 2017. As an integrated Member of the Center for Neuroscience and Cell Biology (CNC-UC) and head of the clinical/translational research group "Biomarkers in Neuropsychiatric Disorders: from Molecules to Diagnosis and Intervention" of the Center for Innovative Biomedicine and Biotechnology. She participates and/or has participated as Principal investigator in 13 project(s) and as Researcher in 26 project(s) with competitive financial support, received 26 awards and/or honors, is author/co-author of over 250 papers (6492 citations/h factor: 41), 31 books/section(s) of books and of more than 500 oral presentations in national and/or international scientific meetings. She has supervised/co-supervised 10 PhD thesis and 51 MSc dissertations.
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Publications

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Subject:  Aged
Fulltext:  Com Texto completo

Results 1-13 of 13 (Search time: 0.039 seconds).

Issue DateTitleAuthor(s)TypeAccess
120-Mar-2018Addition of the Aβ42/40 ratio to the cerebrospinal fluid biomarker profile increases the predictive value for underlying Alzheimer's disease dementia in mild cognitive impairmentBaldeiras, Inês ; Santana, Isabel ; Leitão, Maria João ; Gens, Helena; Pascoal, Rui; Tábuas-Pereira, Miguel ; Beato-Coelho, José; Duro, Diana ; Almeida, Maria do Rosário ; Oliveira, Catarina Resende de articleopenAccess
230-May-2018Aphasia Rapid Test: Estudos de Tradução, Adaptação e Validação para a População PortuguesaTábuas-Pereira, Miguel ; Freitas, Sandra ; Beato-Coelho, José; Ribeiro, Joana; Parra, Joana; Martins, Cristina ; Silva, Miguel; Matos, Maria Assunção; Nogueira, Ana Rita; Silva, Fernando; Sargento-Freitas, João ; Cordeiro, Gustavo ; Cunha, Luís ; Santana, Isabel articleopenAccess
330-Jan-2020Cerebrospinal fluid lipocalin 2 as a novel biomarker for the differential diagnosis of vascular dementiaLlorens, Franc; Hermann, Peter; Villar-Piqué, Anna; Diaz-Lucena, Daniela; Nägga, Katarina; Hansson, Oskar; Santana, Isabel ; Schmitz, Matthias; Schmidt, Christian; Varges, Daniela; Goebel, Stefan; Dumurgier, Julien; Zetterberg, Henrik; Blennow, Kaj; Paquet, Claire; Baldeiras, Inês ; Ferrer, Isidro; Zerr, IngaarticleopenAccess
423-Nov-2019Clinical validation of the Lumipulse G cerebrospinal fluid assays for routine diagnosis of Alzheimer's diseaseLeitão, Maria João ; Spínola, Anuschka da Silva ; Santana, Isabel ; Olmedo, Veronica; Nadal, Alicia; Le Bastard, Nathalie; Baldeiras, Inês articleopenAccess
52018Data driven diagnostic classification in Alzheimer's disease based on different reference regions for normalization of PiB-PET images and correlation with CSF concentrations of Aβ speciesOliveira, Francisco ; Leuzy, Antoine; Castelhano, J. ; Chiotis, Konstantinos; Hasselbalch, Steen Gregers; Rinne, Juha; Mendonça, Alexandre de ; Otto, Markus; Lleó, Alberto ; Santana, Isabel ; Johansson, Jarkko; Anderl-Straub, Sarah; Arnim, Christine; Beer, Ambros; Blesa, Rafael ; Fortea, Juan; Sanna-Kaisa, Herukka; Portelius, Erik; Pannee, Josef; Zetterberg, Henrik; Blennow, Kaj; Moreira, Ana P. ; Abrunhosa, Antero ; Nordberg, Agneta; Castelo-Branco, Miguel articleopenAccess
65-Jan-2019Erlangen Score as a tool to predict progression from mild cognitive impairment to dementia in Alzheimer's diseaseBaldeiras, Inês ; Santana, Isabel ; Leitão, Maria João ; Vieira, Daniela ; Duro, Diana; Mroczko, Barbara; Kornhuber, Johannes; Lewczuk, PiotrarticleopenAccess
728-Nov-2019Evaluation of Human Cerebrospinal Fluid Malate Dehydrogenase 1 as a Marker in Genetic Prion Disease PatientsZerr, Inga; Villar-Piqué, Anna; Schmitz, Vanda Edit; Poleggi, Anna; Pocchiari, Maurizio; Sánchez-Valle, Raquel ; Calero, Miguel; Calero, Olga; Baldeiras, Inês ; Santana, Isabel ; Kovacs, Gabor G.; Llorens, Franc; Schmitz, MatthiasarticleopenAccess
817-Nov-2020Increased C-X-C Motif Chemokine Ligand 12 Levels in Cerebrospinal Fluid as a Candidate Biomarker in Sporadic Amyotrophic Lateral SclerosisAndrés-Benito, Pol; Povedano, Mònica; Domínguez, Raúl; Marco, Carla; Colomina, Maria J.; López-Pérez, Óscar; Santana, Isabel ; Baldeiras, Inês ; Martínez-Yelámos, Sergio; Zerr, Inga; Llorens, Franc; Fernández-Irigoyen, Joaquín; Santamaría, Enrique; Ferrer, IsidroarticleopenAccess
9Apr-2016Mini-mental state examination: Avaliação dos novos dados normativos no rastreio e diagnóstico do défice cognitivoSantana, Isabel ; Duro, Diana ; Lemos, Raquel; Costa, Vanessa ; Pereira, Miguel; Simões, Mário R. ; Freitas, Sandra articleopenAccess
104-Jan-2021Progression of Behavioral Disturbances and Neuropsychiatric Symptoms in Patients With Genetic Frontotemporal DementiaBenussi, Alberto; Premi, Enrico; Gazzina, Stefano; Brattini, Chiara; Bonomi, Elisa; Alberici, Antonella; Jiskoot, Lize; van Swieten, John C; Sánchez-Valle, Raquel ; Moreno, Fermin; Laforce, Robert; Graff, Caroline; Synofzik, Matthis; Galimberti, Daniela; Masellis, Mario; Tartaglia, Carmela; Rowe, James B; Finger, Elizabeth; Vandenberghe, Rik; de Mendonça, Alexandre; Tagliavini, Fabrizio ; Santana, Isabel ; Ducharme, Simon; Butler, Chris R; Gerhard, Alexander; Levin, Johannes; Danek, Adrian; Otto, Markus; Frisoni, Giovanni; Ghidoni, Roberta; Sorbi, Sandro; Le Ber, Isabelle; Pasquier, Florence; Peakman, Georgia; Todd, Emily; Bocchetta, Martina; Rohrer, Jonathan D. ; Borroni, Barbara; Afonso, Sónia ; Leitão, Maria João ; et al.articleopenAccess
112019Retinal texture biomarkers may help to discriminate between Alzheimer's, Parkinson's, and healthy controlsNunes, Ana ; Silva, Gilberto ; Duque, Cristina; Januário, Cristina ; Santana, Isabel ; Ambrósio, António ; Castelo-Branco, Miguel ; Bernardes, Rui articleopenAccess
122019Semi-quantification and grading of amyloid PET: A project of the European Alzheimer's Disease Consortium (EADC)Chincarini, A.; Peira, E.; Morbelli, S.; Pardini, M.; Bauckneht, M.; Arbizu, J.; Castelo-Branco, Miguel ; Büsing, K. A.; de Mendonça, A.; Didic, M.; Dottorini, M.; Engelborghs, S.; Ferrarese, C.; Frisoni, G. B.; Garibotto, V.; Guedj, E.; Hausner, L.; Hugon, J.; Verhaeghe, J.; Mecocci, P.; Musarra, M.; Queneau, M.; Riverol, M.; Santana, Isabel ; Guerra, U. P.; Nobili, F.articleopenAccess
132019White matter hyperintensities in progranulin-associated frontotemporal dementia: A longitudinal GENFI studySudre, Carole H.; Bocchetta, Martina; Heller, Carolin; Convery, Rhian; Neason, Mollie; Moore, Katrina M.; Cash, David M.; Thomas, David L.; Woollacott, Ione O. C.; Foiani, Martha; Heslegrave, Amanda; Shafei, Rachelle; Greaves, Caroline; van Swieten, John; Moreno, Fermin; Sánchez-Valle, Raquel ; Borroni, Barbara; Laforce, Robert; Masellis, Mario; Tartaglia, Maria Carmela; Graff, Caroline; Galimberti, Daniela; Rowe, James B; Finger, Elizabeth; Synofzik, Matthis; Vandenberghe, Rik; de Mendonça, Alexandre; Tagliavini, Fabrizio ; Santana, Isabel ; Ducharme, Simon; Butler, Chris; Gerhard, Alex; Levin, Johannes; Danek, Adrian; Frisoni, Giovanni B; Sorbi, Sandro; Otto, Markus; Zetterberg, Henrik; Ourselin, Sebastien; Cardoso, M Jorge; Rohrer, Jonathan D. articleopenAccess