Irina S. Moreira acknowledges support by the Fundação para a Ciência e a Tecnologia (FCT) Investigator programme - IF/00578/2014 (co-financed by European Social Fund and Programa Operacional Potencial Humano), and a Marie Skłodowska-Curie Individual Fellowship MSCA-IF-2015 [MEMBRANEPROT 659826]. This work was also financed by the European Regional Development Fund (ERDF), through the Centro 2020 Regional Operational Programme under project CENTRO-01-0145-FEDER-000008: BrainHealth 2020, and through the COMPETE 2020 - Operational Programme for Competitiveness and Internationalisation and Portuguese national funds via FCT, under project POCI-01-0145-FEDER-007440. Rita Melo acknowledges support from the FCT (FCT—SFRH/BPD/97650/2013). Jörg Schaarschmidt acknowledges support from the European H2020 e-Infrastructure grant West-Life grant no. 675858. Mikael Trellet acknowledges support from the European H2020 e-Infrastructure grants West-Life grant no. 675858 and BioExcel grant no. 675728. Panagiotis Koukos and Alexandre Bonvin acknowledge financial support from the Dutch Foundation for Scientific Research (NWO) (TOP-PUNT grant 718.015.001). Zeynep H. Gümüş acknowledges financial support from start-up funds at Icahn School of Medicine at Mount Sinai.