info:eu-repo/grantAgreement/EC/H2020/72261

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Primary Data

Project title
info:eu-repo/grantAgreement/EC/H2020/72261
Code
FOIE GRAS -Bioenergetic Remodeling in the Pathophysiology and Treatment of Non-Alcoholic Fatty Liver Disease
Organization
 
Status
On going
Start date
01-01-2017
Expected Completion
30-06-2021
 

Description

Abstract
FOIE GRAS provides innovative training for 13 early stage researchers (ESRs) to answer two critical and unanswered questions: a) Is hepatic bioenergetic remodelling involved in NAFLD pathogenesis, and target for stratification or therapeutic/lifestyle interventions? and b) Is the disruption of the gut-liver axis involved in NAFLD progression? In Western Societies, there has been a recent surge of non-alcoholic fatty liver disease (NAFLD). Its progression to nonalcoholic steatohepatitis (NASH) is a leading risk factor for development of Type 2 diabetes, cirrhosis, and hepatocellular carcinoma. FOIE GRAS is first in supporting a cohesive and synergistic intersection of complementary and interdisciplinary training skills from academic and non-academic partners. FOIE GRAS combines strong scientific expertise with integrated and complementary training in translational research, clinical practice, technology commercialization, and public outreach, the combination of which in targeting NAFLD is lacking in the EU. Industrial partners CETICS, Mediagnost and Seahorse Biosciences provide experience on technology commercialization alongside scientific contributions while the affiliated patient organization will contribute with important training in societal awareness topics. ESRs training will utilize network-wide workshops and secondments to foster translation of basic research to clinical applications and SME creation. This diverse yet integrated skill set enhances the employment prospects of the trained researchers in both academic and non-academic sectors. Researchers will be endowed with excellent basic scientific knowledge and timely technology transfer know-how for developing novel therapeutic approaches for reversing the burden of NAFLD, thereby advancing both health and economic well-being of Europea
 
Keyword(s)
MSCA-ITN-2016 - Innovative Training Networks

Publications
(All)

Results 21-27 of 27 (Search time: 0.025 seconds).

Issue DateTitleAuthor(s)TypeAccess
2129-Nov-2021A mother's heart: impacts of gestation habits on maternal cardiac mitochondria metabolismSantos, Carolina Tocantins de FigueiredomasterThesisembargoedAccess
22Mar-2022Mushrooms on the plate: Trends towards NAFLD treatment, health improvement and sustainable dietsFontes, Adriana ; Ramalho-Santos, João ; Zischka, Hans; Azul, Anabela Marisa de Jesus Rodrigues articleopenAccess
23Feb-2019Targeting mitochondria to oppose the progression of nonalcoholic fatty liver diseaseGrattagliano, Ignazio; Montezinho, Liliana P. ; Oliveira, Paulo J. ; Frühbeck, Gema; Gómez-Ambrosi, Javier; Montecucco, Fabrizio; Carbone, Federico; Wieckowski, Mariusz R. ; Wang, David Q-H; Portincasa, PieroarticleembargoedAccess
24Oct-2020The mystery of mitochondria-ER contact sites in physiology and pathology: A cancer perspectiveSimoes, Ines C M; Morciano, Giampaolo; Lebiedzinska-Arciszewska, Magdalena; Aguiari, Gianluca; Pinton, Paolo; Potes, Yaiza; Wieckowski, Mariusz R. articleembargoedAccess
25Jan-2020The role of mitochondria-associated membranes in cellular homeostasis and diseasesPerrone, Mariasole; Caroccia, Natascia; Genovese, Ilaria; Missiroli, Sonia; Modesti, Lorenzo; Pedriali, Gaia; Vezzani, Bianca; Vitto, Veronica Angela Maria; Antenori, Michele; Lebiedzinska-Arciszewska, Magdalena; Wieckowski, Mariusz R. ; Giorgi, Carlotta; Pinton, PaolobookembargoedAccess
26Dec-2020The role of the liver in the modulation of glucose and insulin in non alcoholic fatty liver disease and type 2 diabetesGuerra, Sara Isabel da Silva ; Gastaldelli, AmaliaarticleembargoedAccess
2715-Oct-2020Western Diet Causes Obesity-Induced Nonalcoholic Fatty Liver Disease Development by Differentially Compromising the Autophagic ResponseSimoes, Ines C M; Karkucinska-Wieckowska, Agnieszka; Janikiewicz, Justyna; Szymanska, Sylwia; Pronicki, Maciej; Dobrzyn, Pawel; Dabrowski, Michal; Dobrzyn, Agnieszka; Oliveira, Paulo J. ; Zischka, Hans; Potes, Yaiza; Wieckowski, Mariusz R. articleopenAccess