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Issue Date | Title | Author(s) | Type | Access |
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19-Apr-2022 | Alchemical Design of Pharmacological Chaperones with Higher Affinity for Phenylalanine Hydroxylase | Conde-Giménez, María; Galano-Frutos, Juan José; Galiana-Cameo, María; Mahía, Alejandro; Victor, Bruno L. ; Salillas, Sandra; Velázquez-Campoy, Adrián; Brito, Rui M. M. ; Gálvez, José Antonio; Díaz-de-Villegas, María D.; Sancho, Javier | article | openAccess |
2020 | An Innovative Sequence-to-Structure-Based Approach to Drug Resistance Interpretation and Prediction: The Use of Molecular Interaction Fields to Detect HIV-1 Protease Binding-Site Dissimilarities | Alves, Nuno G. ; Mata, Ana I. ; Luís, João P. ; Brito, Rui M. M. ; Simões, Carlos J. V. | article | openAccess |
2016 | Cell Spotting: educational and motivational outcomes of cell biology citizen science project in the classroom | Brito, Rui M. M. ; Carrodeguas, Jose; Serrano Sanz, Fermin; Mota, Paulo ; Brasileiro, Francisco; Andrade, Nazareno; Schäfer, Teresa; Lostal, Eduardo; Manahl, Caroline; Monteiro, Antonio; Silva, Cândida G. | article | openAccess |
2012 | Changes in channel trafficking and protein stability caused by LQT2 mutations in the PAS domain of the HERG channel | Harley, Carol A.; Jesus, Catarina S. H. ; Carvalho, Ricardo; Brito, Rui M. M. ; Morais-Cabral, João H. | article | openAccess |
Sep-2010 | Cinética de agregação da proteína transtirretina: contribuição para a compreensão dos processos de formação de amilóide | Almeida, Zaida C. Lourenço de | masterThesis | openAccess |
2000 | Comparative calorimetric study of non-amyloidogenic and amyloidogenic variants of the homotetrameric protein transthyretin | Shnyrov, Valery L. ; Villar, Enrique ; Zhadan, Galina G. ; Sanchez-Ruiz, Jose M. ; Quintas, Alexandre ; Saraiva, Maria João M. ; Brito, Rui M. M. | article | openAccess |
26-Feb-2022 | Conformational Dynamics of the Soluble and Membrane-Bound Forms of Interleukin-1 Receptor Type-1: Insights into Linker Flexibility and Domain Orientation | Luís, João P. ; Mata, Ana I. ; Simões, Carlos J. V. ; Brito, Rui M. M. | article | openAccess |
Feb-2016 | Em busca de determinantes estruturais no reconhecimento e ligação de amilóide: β-2 microglobulina como caso de estudo | Fernandes, Pedro Miguel Pinto | masterThesis | openAccess |
2012 | Uma estratégia para a discriminação entre compostos activos e inactivos em experiências de rastreio virtual : COX-1 como caso de estudo | Carreiras, Pedro Miguel Serrano Germano Calado | masterThesis | openAccess |
27-Sep-2017 | Estudo das alterações metabólicas post mortem no fígado por espectroscopia de RMN | Tomé, Ana Sofia Monteiro | masterThesis | openAccess |
2016 | Hereditary nonspherocytic hemolytic anemia caused by red cell glucose-6-phosphate isomerase (GPI) deficiency in two Portuguese patients: Clinical features and molecular study | Manco, Licínio ; Bento, Celeste ; Victor, Bruno L. ; Pereira, Janet ; Relvas, Luís ; Brito, Rui M. ; Seabra, Carlos ; Maia, Tabita M. ; Ribeiro, M. Letícia | article | openAccess |
Sep-2015 | Identification and characterization of small molecule interactions with transthyretin amyloid fibers | Ferreira, Elisabete Priscila Pinto | masterThesis | openAccess |
31-Jan-2014 | Kinetics and Energetics of Fundamental Events in Peptide and Protein (Un)Folding | Jesus, Catarina Sofia Henriques de | doctoralThesis | embargoedAccess |
14-Nov-2020 | Ligand-Targeted Delivery of Photosensitizers for Cancer Treatment | Gierlich, Piotr ; Mata, Ana I. ; Donohoe, Claire ; Brito, Rui M. M. ; Senge, Mathias O. ; Silva, Lígia C. Gomes da | article | openAccess |
31-Aug-2016 | A New Folding Kinetic Mechanism for Human Transthyretin and the Influence of the Amyloidogenic V30M Mutation | Jesus, Catarina S. H. ; Almeida, Zaida L. ; Vaz, Daniela C. ; Faria, Tiago Q. ; Brito, Rui M. M. | article | openAccess |
3-Dec-2020 | Oligomerization Profile of Human Transthyretin Variants with Distinct Amyloidogenicity | Frangolho, Ana; Correia, Bruno E.; Vaz, Daniela C. ; Almeida, Zaida L. ; Brito, Rui M. M. | article | openAccess |
26-Sep-2019 | OSA and Transthyretin | Santos, Alexander Michael Ribeiro | masterThesis | embargoedAccess |
25-Sep-2019 | O papel dos halogénios no desenho de fármacos. O caso da ligação de pequenos ligantes à Transtirretina. | Caniceiro, Ana Beatriz Ramos | masterThesis | openAccess |
15-Nov-2010 | Protein conformational plasticity and aggregation : transthyretin and δ-toxin as two case studies | Ferreira, Nuno Ricardo Santos Loureiro da Silva | doctoralThesis | openAccess |
30-Dec-2021 | Searching for the Best Transthyretin Aggregation Protocol to Study Amyloid Fibril Disruption | Ferreira, Elisabete ; Almeida, Zaida L. ; Cruz, Pedro F. ; Sousa, Marta Silva e ; Veríssimo, Paula ; Brito, Rui M. M. | article | openAccess |