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https://hdl.handle.net/10316/95085| Title: | Mechanisms for increased risk of diabetes in chronic liver diseases | Authors: | Svegliati-Baroni, Gianluca Gaggini, Melania Carli, Fabrizia Barbieri, Chiara Cucco, Monica Youne, Ramy Rosso, Chiara Bugianesi, Elisabetta Gastaldelli, Amalia |
Issue Date: | Jun-2020 | Publisher: | Wiley Online Library | Project: | info:eu-repo/grantAgreement/EC/H2020/634413/EU/Elucidating Pathways of Steatohepatitis info:eu-repo/grantAgreement/EC/H2020/691042/EU/Mastiha treatment for healthy obese with NAFLD diagnosis (MAST4HEALTH). info:eu-repo/grantAgreement/EC/H2020/72261 |
Serial title, monograph or event: | Liver International | Volume: | 40 | Issue: | 10 | Abstract: | Patients with chronic liver disease (CLD), both non-alcoholic fatty liver disease (NAFLD) and chronic hepatitis C (CHC), are at high risk of diabetes (T2D), but mechanisms are still unknown. Muscle/liver insulin resistance (IR) and pancreatic dysfunction are the major metabolic defects leading to T2D. However, if the risk of T2D in CLD patients is because of reduced insulin response and/or to IR, and the impact of liver histology has not been investigated. | URI: | https://hdl.handle.net/10316/95085 | ISSN: | 1478-3223 1478-3231 |
DOI: | 10.1111/liv.14556 | Rights: | embargoedAccess |
| Appears in Collections: | I&D CNC - Artigos em Revistas Internacionais |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| paper HCV NAFLD beta cell LiverInt 2020.pdf | 706.78 kB | Adobe PDF | View/Open |
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