Drug delivery from an ocular implant into the vitreous chamber of the eye

Abstract

A mathematical model which simulates drug delivery from an ocular implant into the vitreous chamber of the eye is proposed. The model consists of coupled systems of partial differential equations linked by interface conditions. The chemical structure, the viscoelastic properties and the diffusion phenomena are taken into account to simulate the evolution of released drug. Numerical simulations that illustrate the interplay between these phenomena are included.