Please use this identifier to cite or link to this item:
https://hdl.handle.net/10316/114147
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Carneiro, Liliana P.T. | - |
dc.contributor.author | Pinto, Alexandra M.F.R. | - |
dc.contributor.author | Sales, M. Goreti F. | - |
dc.date.accessioned | 2024-03-21T12:38:21Z | - |
dc.date.available | 2024-03-21T12:38:21Z | - |
dc.date.issued | 2023 | - |
dc.identifier.issn | 13858947 | pt |
dc.identifier.uri | https://hdl.handle.net/10316/114147 | - |
dc.description.abstract | This work describes for the first time a paper-based direct methanol fuel cell platform (PB-DMFC) that functions as an energy source and biosensor, assembled on a simple paper substrate for point-of-care (POC) applications, targeting sarcosine as proof-of-concept. Specifically, a methanol fuel cell strip was developed from a square of Whatman paper, acting as substrate. The paper strip was treated with an impermeable agent (paraffin solution) and supported all fuel cell device components, including the electrolyte (Nafion®), anode electrode (carbon black Pt/Ru), cathode electrode (carbon black Pt), and current collectors (silver edges). All the described components formed a flexible single layer that operated in a completely passive mode by adding few microliters of a methanol solution on the anode side and by using atmospheric oxygen on the cathode side. The obtained platform had a stable electrical signal with an average OCV value of 0.45–0.55 V and a maximum power density of 20–50 μW/cm2, depending on the methanol concentration used (0.5 M–2 M). A sensing layer was built in situ on the anode electrode by electropolymerization of a solution of 3,4-ethylenedioxythiophene (EDOT) and pyrrole (Py) as monomers. The obtained PB-DMFC/biosensor was calibrated at room temperature in buffer and healthy human urine and showed linear responses from 1.0 × 10 7 to 1.0 × 10 3 M with a detection limit of 6.6 × 10 8 M. Selectivity studies evidenced signals changing within 1–10%, both in positive and negative directions. Results evidenced good reproducibility. Overall, the obtained results demonstrate a self-sufficient biosensor for the detection of sarcosine consisting of an innovative paper-based methanol fuel cell strip. This concept can open new horizons for massification of biosensors even in places with energy shortage. | pt |
dc.language.iso | eng | pt |
dc.publisher | Elsevier | pt |
dc.relation | The authors acknowledge the financial support of EU-Horizon 2020 (Symbiotic, FET-Open, GA665046) and LPTC (Grant references: SFRH/ BD/122954/2016; COVID/BD/151738/2021) acknowledges Fundaç˜ao para a Ciˆencia e Tecnologia (FCT) for financial support. This work was also financially supported by LA/P/0045/2020 (ALiCE), UIDB/00532/ 2020 and UIDP/00532/2020 (CEFT), funded by national funds through FCT/MCTES (PIDDAC) | pt |
dc.rights | openAccess | pt |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | pt |
dc.subject | Paper-based methanol fuel cell | pt |
dc.subject | Sensing platform | pt |
dc.subject | Molecularly imprinted polymer | pt |
dc.subject | Sarcosine | pt |
dc.subject | Point of care | pt |
dc.subject | Cancer biomarker | pt |
dc.title | Development of an innovative flexible paper-based methanol fuel cell (PB-DMFC) sensing platform – Application to sarcosine detection | pt |
dc.type | article | - |
degois.publication.firstPage | 139563 | pt |
degois.publication.title | Chemical Engineering Journal | pt |
dc.peerreviewed | yes | pt |
dc.identifier.doi | 10.1016/j.cej.2022.139563 | pt |
degois.publication.volume | 452 | pt |
dc.date.embargo | 2023-01-01 | * |
uc.date.periodoEmbargo | 0 | pt |
item.grantfulltext | open | - |
item.cerifentitytype | Publications | - |
item.languageiso639-1 | en | - |
item.openairetype | article | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.fulltext | Com Texto completo | - |
crisitem.author.orcid | 0000-0001-9936-7336 | - |
Appears in Collections: | FCTUC Eng.Química - Artigos em Revistas Internacionais |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
Development of an innovative flexible paper-based methanol fuel cell (PB-DMFC) sensing platform – Application to sarcosine detection.pdf | 7.42 MB | Adobe PDF | View/Open |
Page view(s)
132
checked on May 8, 2024
Download(s)
121
checked on May 8, 2024
Google ScholarTM
Check
Altmetric
Altmetric
This item is licensed under a Creative Commons License