Please use this identifier to cite or link to this item: https://hdl.handle.net/10316/113866
Title: Photoantibacterial Poly(vinyl)chloride Films Applying Curcumin Derivatives as Bio-Based Plasticizers and Photosensitizers
Authors: Rodrigues, Fábio M. S. 
Tavares, Iúri
Aroso, Rafael T. 
Dias, Lucas D. 
Domingos, Carolina V. 
de Faria, Clara M. G.
Piccirillo, Giusi 
Maria, Teresa M. R. 
Carrilho, Rui M. B. 
Bagnato, Vanderlei S.
Calvete, Mário J. F. 
Pereira, Mariette M. 
Keywords: curcumin; PVC films; bioplasticizer; photosensitizer; antimicrobial photodynamic inactivation (aPDT); photosensitive material; photodecontamination
Issue Date: 27-Feb-2023
Publisher: MDPI
Project: This work was funded by FCT—Foundation for Science and Technology, I.P., under projects UIDB/00313/2020,UID/BIA/04004/2020. Furthermore, the authors acknowledge PRR—Recovery and Resilience Plan and the Next Generation EU Funds for funding through Project no 6979-PRODUTECH R3 [Recuperação-Resiliência-Reindustrialização]. G.P. thanks FCT for PhD grant PD/BD/135532/2018. This work was partially supported by MCTIC/FNDCT-CNPq/MEC–CAPES/MS-Decit/N 14/2016 (CNPq 440585/2016–3 and CAPES 88881.130676/2016–01); Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP CEPOF 2013/07276–1, 2018/00106–7, and 2019/13569–8) and INCT “Basic Optics and Applied to Life Sciences” (FAPESP 2014/50857–8, CNPq 465360/2014–9). L.D.D. thanks Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq-Brasil) for Post-doc Grant 151188/2022–0. 
Serial title, monograph or event: Molecules
Volume: 28
Issue: 5
Abstract: Herein we describe the design of natural curcumin ester and ether derivatives and their application as potential bioplasticizers, to prepare photosensitive phthalate-free PVC-based materials. The preparation of PVC-based films incorporating several loadings of newly synthesized curcumin derivatives along with their standard solid-state characterization is also described. Remarkably, the plasticizing effect of the curcumin derivatives in the PVC material was found to be similar to that observed in previous PVC-phthalate materials. Finally, studies applying these new materials in the photoinactivation of S. aureus planktonic cultures revealed a strong structure/activity correlation, with the photosensitive materials reaching up to 6 log CFU reduction at low irradiation intensities.
URI: https://hdl.handle.net/10316/113866
ISSN: 1420-3049
DOI: 10.3390/molecules28052209
Rights: openAccess
Appears in Collections:I&D CQC - Artigos em Revistas Internacionais
FCTUC Química - Artigos em Revistas Internacionais

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