Utilize este identificador para referenciar este registo:
https://hdl.handle.net/10316/113463
Campo DC | Valor | Idioma |
---|---|---|
dc.contributor.author | Suleimenova, Akmaral | - |
dc.contributor.author | Frasco, Manuela F. | - |
dc.contributor.author | Soares da Silva, Francisco A.G. | - |
dc.contributor.author | Gama, Miguel | - |
dc.contributor.author | Fortunato, Elvira | - |
dc.contributor.author | Sales, M. Goreti F. | - |
dc.date.accessioned | 2024-02-20T12:56:11Z | - |
dc.date.available | 2024-02-20T12:56:11Z | - |
dc.date.issued | 2023 | - |
dc.identifier.issn | 25901370 | pt |
dc.identifier.uri | https://hdl.handle.net/10316/113463 | - |
dc.description.abstract | The development of optical biosensors based on structural colors generated by short-range ordered colloidal particles is attracting growing interest due to their non-iridescent and non-fading features. In this study, a biomimetic approach using biopolymers for the various steps of sensor construction is presented. Bacterial nanocellulose (BNC) has many foreseen applications in biomedical engineering because of its biocompatibility, good mechanical strength, and large modifiable surface area. Herein, a novel approach is taken by using functionalized BNC as a substrate to build a molecularly imprinted photonic sensing layer. BNC was modified with polydopamine (PDA), which improved the adhesion and mechanical properties of the BNC substrate while providing simultaneously a black background for color saturation. A molecularly imprinted polymer (MIP) also made of PDA was used to create the recognition sites for the biomarker lysozyme. A monodisperse colloidal suspension of silica particles was first synthesized and used as core of the MIP shell, and then the photonic structure was assembled on the PDA-BNC membrane. The biosensor showed a detection limit of about 0.8 nmol L 1 of lysozyme in spiked human serum and demonstrated to be selective against cystatin C. These properties, combined with biocompatible, eco-friendly, and low-cost materials, offer a sustainable sensing platform with great potential for healthcare applications. | pt |
dc.language.iso | eng | pt |
dc.publisher | Elsevier | pt |
dc.relation | European Commission through the project MindGAP (FET-Open/H2020/ GA829040) | pt |
dc.relation | MIT Portugal PhD grant (PD/BD/142776/2018) funded by Fundação para a Ciência e a Tecnologia (FCT). | pt |
dc.rights | openAccess | pt |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | pt |
dc.subject | Bacterial nanocellulose | pt |
dc.subject | Polydopamine | pt |
dc.subject | Molecular imprinting technology | pt |
dc.subject | Photonic polymers | pt |
dc.subject | Lysozyme | pt |
dc.title | Bacterial nanocellulose membrane as novel substrate for biomimetic structural color materials: Application to lysozyme sensing | pt |
dc.type | article | - |
degois.publication.firstPage | 100310 | pt |
degois.publication.title | Biosensors and Bioelectronics: X | pt |
dc.peerreviewed | yes | pt |
dc.identifier.doi | 10.1016/j.biosx.2023.100310 | pt |
degois.publication.volume | 13 | pt |
dc.date.embargo | 2023-01-01 | * |
uc.date.periodoEmbargo | 0 | pt |
item.fulltext | Com Texto completo | - |
item.languageiso639-1 | en | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.openairetype | article | - |
item.grantfulltext | open | - |
item.cerifentitytype | Publications | - |
crisitem.author.orcid | 0000-0002-1813-8089 | - |
crisitem.author.orcid | 0000-0001-9936-7336 | - |
Aparece nas coleções: | FCTUC Eng.Química - Artigos em Revistas Internacionais |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
---|---|---|---|---|
Bacterial nanocellulose membrane as novel substrate for biomimetic structural color materials Application to lysozyme sensing.pdf | 6.03 MB | Adobe PDF | Ver/Abrir |
Visualizações de página
43
Visto em 24/jul/2024
Downloads
28
Visto em 24/jul/2024
Google ScholarTM
Verificar
Altmetric
Altmetric
Este registo está protegido por Licença Creative Commons