Please use this identifier to cite or link to this item:
https://hdl.handle.net/10316/113124
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Marques, Mário Pedro | - |
dc.contributor.author | Varela, Carla Lopes | - |
dc.contributor.author | Mendonça, Laura | - |
dc.contributor.author | Cabral, Célia | - |
dc.date.accessioned | 2024-02-06T10:45:11Z | - |
dc.date.available | 2024-02-06T10:45:11Z | - |
dc.date.issued | 2023-06-14 | - |
dc.identifier.issn | 1999-4923 | - |
dc.identifier.uri | https://hdl.handle.net/10316/113124 | - |
dc.description.abstract | Atopic dermatitis (AD) is a chronic eczematous inflammatory disease that may arise from environmental, genetic, and immunological factors. Despite the efficacy of current treatment options such as corticosteroids, such approaches are mainly focused on symptom relief and may present certain undesirable side effects. In recent years, isolated natural compounds, oils, mixtures, and/or extracts have gained scientific attention because of their high efficiency and moderate to low toxicity. Despite their promising therapeutic effects, the applicability of such natural healthcare solutions is somewhat limited by their instability, poor solubility, and low bioavailability. Therefore, novel nanoformulation-based systems have been designed to overcome these limitations, thus enhancing the therapeutic potential, by promoting the capacity of these natural drugs to properly exert their action in AD-like skin lesions. To the best of our knowledge, this is the first literature review that has focused on summarizing recent nanoformulation-based solutions loaded with natural ingredients, specifically for the management of AD. We suggest that future studies should focus on robust clinical trials that may confirm the safety and effectiveness of such natural-based nanosystems, thus paving the way for more reliable AD treatments. | pt |
dc.language.iso | eng | pt |
dc.publisher | MDPI | pt |
dc.relation | COA/BRB/0019/2019 | pt |
dc.relation | UIDB/04539/2020 | pt |
dc.relation | info:eu-repo/grantAgreement/UIDP/04539/2020 | pt |
dc.relation | LA/P/0058/2020 | pt |
dc.relation | PRT/BD/153391/2021 | pt |
dc.rights | openAccess | pt |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | pt |
dc.subject | atopic dermatitis | pt |
dc.subject | skin inflammation | pt |
dc.subject | natural products | pt |
dc.subject | nanotechnology | pt |
dc.subject | topical delivery | pt |
dc.title | Nanotechnology-Based Topical Delivery of Natural Products for the Management of Atopic Dermatitis | pt |
dc.type | article | pt |
degois.publication.firstPage | 1724 | pt |
degois.publication.issue | 6 | pt |
degois.publication.title | Pharmaceutics | pt |
dc.peerreviewed | yes | pt |
dc.identifier.doi | 10.3390/pharmaceutics15061724 | - |
degois.publication.volume | 15 | pt |
dc.date.embargo | 2023-06-14 | * |
dc.identifier.pmid | 37376172 | - |
uc.date.periodoEmbargo | 0 | pt |
item.openairetype | article | - |
item.cerifentitytype | Publications | - |
item.languageiso639-1 | en | - |
item.fulltext | Com Texto completo | - |
item.grantfulltext | open | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
crisitem.author.researchunit | CIBB - Center for Innovative Biomedicine and Biotechnology | - |
crisitem.author.researchunit | CIBB - Center for Innovative Biomedicine and Biotechnology | - |
crisitem.author.researchunit | ICBR Coimbra Institute for Clinical and Biomedical Research | - |
crisitem.author.parentresearchunit | Faculty of Medicine | - |
crisitem.author.orcid | 0000-0002-5414-366X | - |
crisitem.author.orcid | 0000-0003-4562-6683 | - |
crisitem.project.grantno | Center for Innovative Biomedicine and Biotechnology - CIBB | - |
crisitem.project.grantno | Center for Innovative Biomedicine and Biotechnology | - |
crisitem.project.grantno | Center for Innovative Biomedicine and Biotechnology - Associate Laboratory | - |
Appears in Collections: | FMUC Medicina - Artigos em Revistas Internacionais I&D CFE - Artigos em Revistas Internacionais I&D CIBB - Artigos em Revistas Internacionais FCTUC Ciências da Vida - Artigos em Revistas Internacionais I&D CIEPQPF - Artigos em Revistas Internacionais I&D ICBR - Artigos em Revistas Internacionais |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
NanotechnologyBased-Topical-Delivery-of-Natural-Products-for-the-Management-of-Atopic-DermatitisPharmaceutics.pdf | 1.35 MB | Adobe PDF | View/Open |
SCOPUSTM
Citations
4
checked on Jun 24, 2024
WEB OF SCIENCETM
Citations
4
checked on Jun 2, 2024
Page view(s)
54
checked on Jun 26, 2024
Download(s)
109
checked on Jun 26, 2024
Google ScholarTM
Check
Altmetric
Altmetric
This item is licensed under a Creative Commons License