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https://hdl.handle.net/10316/110951| Title: | Electrochemical DNA Sensors for Detection of DNA Damage | Authors: | Diculescu, Victor Constantin Chiorcea-Paquim, Ana Maria Brett, Ana Maria |
Keywords: | DNA-electrochemical biosensor; DNA damage; damage to DNA bases; oxidative stress; biomarker of DNA damage; 8-oxo-7,8-dihydroxguanine (8-oxoGua); 8- oxo-7,8-dihydro-2’-deoxyguanosine (8-oxodGuo). | Issue Date: | 2005 | Publisher: | MDPI | Project: | SFRH /BPD/14425/2003 SFRH/BPD/18824/2004 POCTI (co-financed by the European Community Fund FEDER) and ICEMS (Research Unit 103) |
Serial title, monograph or event: | Sensors | Volume: | 5 | Issue: | 6 | Abstract: | Electrochemical devices have received particular attention due to their rapid detection and great sensitivity for the evaluation of DNA-hazard compounds interaction mechanisms. Several types of bioanalytical method use nucleic acids probes to detect DNA damage. This article reviews current directions and strategies in the development and applications of electrochemical DNA sensors for the detection of DNA damage. | URI: | https://hdl.handle.net/10316/110951 | ISSN: | 1424-8220 | DOI: | 10.3390/s5060377 | Rights: | openAccess |
| Appears in Collections: | FCTUC Química - Artigos em Revistas Internacionais |
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| File | Description | Size | Format | |
|---|---|---|---|---|
| Electrochemical-DNA-sensors-for-detection-of-DNA-damageSensors.pdf | 328.77 kB | Adobe PDF | View/Open |
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