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Título: | Influence of surface features on the adhesion of Staphylococcus epidermidis to Ag-TiCN thin films | Autor: | Carvalho, Isabel Henriques, Mariana Oliveira, João Almeida Alves, Cristiana Filipa Piedade, Ana Paula Carvalho, Sandra |
Palavras-chave: | sputtering; microorganism adhesion; biofilm; hydrophobicity; biomaterial | Data: | Jun-2013 | Editora: | Taylor & Francis | Projeto: | SFRH / BD / 67022 / 2009 PEST-C/FIS/UI607/2011 PEST-C/EME/UI0285/2011 PTDC/CTM/102853/2008 |
Título da revista, periódico, livro ou evento: | Science and Technology of Advanced Materials | Volume: | 14 | Número: | 3 | Resumo: | Staphylococcus epidermidis has emerged as one of the major nosocomial pathogens associated with infections of implanted medical devices. The initial adhesion of these organisms to the surface of biomaterials is assumed to be an important stage in their colonization. The main objective of this work is to assess the influence of surface features on the adhesion of S. epidermidis to Ag-TiCN coatings deposited by dc reactive magnetron sputtering. The structural results obtained by x-ray diffraction show that the coatings crystallize in a B1-NaCl crystal structure typical of TiC0.3N0.7. The increase of Ag content promoted the formation of Ag crystalline phases. According to the results obtained with atomic force microscopy, a decrease on the surface roughness of the films from 39 to 7 nm is observed as the Ag content increases from 0 to 15 at.%. Surface energy results show that the increase of Ag promotes an increase in hydrophobicity. Bacterial adhesion and biofilm formation on coatings were assessed by the enumeration of the number of viable cells. The results showed that the surface with lower roughness and higher hydrophobicity leads to greater bacterial adhesion and biofilm formation, highlighting that surface morphology and hydrophobicity rule the colonization of materials. | URI: | https://hdl.handle.net/10316/109810 | ISSN: | 1468-6996 | DOI: | 10.1088/1468-6996/14/3/035009 | Direitos: | openAccess |
Aparece nas coleções: | FCTUC Eng.Mecânica - Artigos em Revistas Internacionais |
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Ficheiro | Descrição | Tamanho | Formato | |
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Influence of surface features on the adhesion of Staphylococcus epidermidis to Ag TiCN thin films.pdf | 2.62 MB | Adobe PDF | Ver/Abrir |
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