Utilize este identificador para referenciar este registo:
https://hdl.handle.net/10316/107496
Campo DC | Valor | Idioma |
---|---|---|
dc.contributor.author | Brandão, Pedro | - |
dc.contributor.author | Pineiro, Marta | - |
dc.contributor.author | Burke, Anthony J. | - |
dc.date.accessioned | 2023-07-17T08:07:56Z | - |
dc.date.available | 2023-07-17T08:07:56Z | - |
dc.date.issued | 2022 | - |
dc.identifier.issn | 0039-7881 | pt |
dc.identifier.issn | 1437-210X | pt |
dc.identifier.uri | https://hdl.handle.net/10316/107496 | - |
dc.description.abstract | Tryptanthrin is a golden-yellow, naturally occurring alkaloid that can be obtained from multiple sources and through different synthetic methodologies. This tetracyclic compound displays several relevant biological activities. The potential of this tetracyclic alkaloid has been widely explored, and several researchers have focused their attention on expanding the variety of tryptanthrin derivatives by using a range of synthetic strategies. In this short review, we aim to address recent developments in the synthesis of the tryptanthrin core, as well as the development of new strategies employed by synthetic organic chemists to obtain novel tryptanthrin derivatives with potential biological activity, using different tools from the chemists’ toolbox, such as photocatalysis, solvent-free approaches, and multicomponent reactions. | pt |
dc.language.iso | eng | pt |
dc.publisher | Thieme | pt |
dc.relation | FCT - PhD grant PD/BD/128490/2017 - CATSUS FCT-PhD Program (PD/00248/2012) | pt |
dc.relation | UIDB/00313/2020 | pt |
dc.relation | UIDP/00313/2020 | pt |
dc.relation | UIDB/50006/2020 | pt |
dc.rights | openAccess | pt |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | pt |
dc.subject | tryptanthrin | pt |
dc.subject | indoloquinazoline derivatives | pt |
dc.subject | bioactive compounds | pt |
dc.subject | drug design | pt |
dc.title | Tryptanthrin and Its Derivatives in Drug Discovery: Synthetic Insights | pt |
dc.type | article | pt |
degois.publication.firstPage | 4235 | pt |
degois.publication.lastPage | 4245 | pt |
degois.publication.issue | 19 | pt |
degois.publication.title | Synthesis | pt |
dc.peerreviewed | yes | pt |
dc.identifier.doi | 10.1055/s-0040-1719901 | pt |
degois.publication.volume | 54 | pt |
dc.date.embargo | 2022-01-01 | * |
uc.date.periodoEmbargo | 0 | pt |
item.fulltext | Com Texto completo | - |
item.languageiso639-1 | en | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.openairetype | article | - |
item.grantfulltext | open | - |
item.cerifentitytype | Publications | - |
crisitem.author.researchunit | CQC - Coimbra Chemistry Centre | - |
crisitem.author.researchunit | CQC - Coimbra Chemistry Centre | - |
crisitem.author.parentresearchunit | Faculty of Sciences and Technology | - |
crisitem.author.parentresearchunit | Faculty of Sciences and Technology | - |
crisitem.author.orcid | 0000-0002-1455-7470 | - |
crisitem.author.orcid | 0000-0002-7460-3758 | - |
crisitem.project.grantno | Coimbra Chemistry Center | - |
crisitem.project.grantno | Coimbra Chemistry Center | - |
crisitem.project.grantno | Associated Laboratory for Green Chemistry - Clean Technologies and Processes- REQUIMTE | - |
Aparece nas coleções: | I&D CQC - Artigos em Revistas Internacionais |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
---|---|---|---|---|
Brandao2022Synthesis.pdf | 6.52 MB | Adobe PDF | Ver/Abrir |
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