Please use this identifier to cite or link to this item:
https://hdl.handle.net/10316/107440
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Brandão, Pedro | - |
dc.contributor.author | Marques, Carolina S. | - |
dc.contributor.author | Carreiro, Elisabete P. | - |
dc.contributor.author | Pineiro, Marta | - |
dc.contributor.author | Burke, Anthony J. | - |
dc.date.accessioned | 2023-07-12T09:18:02Z | - |
dc.date.available | 2023-07-12T09:18:02Z | - |
dc.date.issued | 2021-04 | - |
dc.identifier.issn | 1527-8999 | pt |
dc.identifier.issn | 1528-0691 | pt |
dc.identifier.uri | https://hdl.handle.net/10316/107440 | - |
dc.description.abstract | Multicomponent reactions (MCRs) are a valuable tool in diversity-oriented synthesis. Its application to privileged structures is gaining relevance in the fields of organic and medicinal chemistry. Isatin, due to its unique reactivity, can undergo different MCRs, affording multiple interesting scaffolds, namely oxindole-derivatives (including spirooxindoles, bis-oxindoles and 3,3-disubstituted oxindoles) and even, under certain conditions, ring-opening reactions occur that leads to other heterocyclic compounds. Over the past few years, new methodologies have been described for the application of this important and easily available starting material in MCRs. In this review, we explore these novelties, displaying them according to the structure of the final products obtained. | pt |
dc.language.iso | eng | pt |
dc.publisher | Wiley Online Library | pt |
dc.relation | info:eu-repo/grantAgreement/FCT/POR_CENTRO/PD/BD/128490/2017/PT/Sustainable Asymmetric Catalytic Synthesis of Novel Oxindole Hybrids with Potential Biological Activity | pt |
dc.relation | UIDB/50006/2020 | pt |
dc.relation | UIDB/00313/2020 | pt |
dc.rights | embargoedAccess | pt |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | pt |
dc.subject | isatin | pt |
dc.subject | multicomponent reactions | pt |
dc.subject | spiroxindoles | pt |
dc.subject | bis-oxindoles | pt |
dc.subject | 3,3-disubstituted oxindoles | pt |
dc.subject | oxindole | pt |
dc.subject | sustainability | pt |
dc.subject | catalysis | pt |
dc.subject | nanocatalysts | pt |
dc.subject | diversity oriented synthesis | pt |
dc.title | Engaging Isatins in Multicomponent Reactions (MCRs) - Easy Access to Structural Diversity | pt |
dc.type | article | - |
degois.publication.firstPage | 924 | pt |
degois.publication.lastPage | 1037 | pt |
degois.publication.issue | 4 | pt |
degois.publication.title | The Chemical Record | pt |
dc.peerreviewed | yes | pt |
dc.identifier.doi | 10.1002/tcr.202000167 | pt |
degois.publication.volume | 21 | pt |
dc.date.embargo | 2022-04-01 | * |
uc.date.periodoEmbargo | 365 | pt |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.grantfulltext | open | - |
item.openairetype | article | - |
item.languageiso639-1 | en | - |
item.fulltext | Com Texto completo | - |
item.cerifentitytype | Publications | - |
crisitem.project.grantno | Associated Laboratory for Green Chemistry - Clean Technologies and Processes- REQUIMTE | - |
crisitem.project.grantno | Coimbra Chemistry Center | - |
crisitem.author.researchunit | CQC - Coimbra Chemistry Centre | - |
crisitem.author.researchunit | CQC - Coimbra Chemistry Centre | - |
crisitem.author.parentresearchunit | Faculty of Sciences and Technology | - |
crisitem.author.parentresearchunit | Faculty of Sciences and Technology | - |
crisitem.author.orcid | 0000-0002-1455-7470 | - |
crisitem.author.orcid | 0000-0002-7460-3758 | - |
Appears in Collections: | I&D CQC - Artigos em Revistas Internacionais |
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File | Description | Size | Format | |
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Brandao2021ChemRec.pdf | 28.63 MB | Adobe PDF | View/Open |
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