Please use this identifier to cite or link to this item:
https://hdl.handle.net/10316/107309
DC Field | Value | Language |
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dc.contributor.author | Alves, Patrícia | - |
dc.contributor.author | Santos, Marta | - |
dc.contributor.author | Mendes, Sabrina | - |
dc.contributor.author | Miguel, Sónia P. | - |
dc.contributor.author | Sá, Kevin D. de | - |
dc.contributor.author | Cabral, Cátia S. D. | - |
dc.contributor.author | Correia, Ilídio J. | - |
dc.contributor.author | Ferreira, Paula | - |
dc.date.accessioned | 2023-07-03T09:12:07Z | - |
dc.date.available | 2023-07-03T09:12:07Z | - |
dc.date.issued | 2019-04-10 | - |
dc.identifier.issn | 2073-4360 | pt |
dc.identifier.uri | https://hdl.handle.net/10316/107309 | - |
dc.description.abstract | Recently, the biomedical scientists who are working in the skin regeneration area have proposed asymmetric membranes as ideal wound dressings, since they are able to reproduce both layers of skin and improve the healing process as well as make it less painful. Herein, an electrospinning technique was used to produce new asymmetric membranes. The protective layer was composed of a blending solution between polycaprolactone and polylactic acid, whereas the underlying layer was comprised of methacrylated gelatin and chitosan. The chemical/physical properties, the in vitro hemo- and biocompatibility of the nanofibrous membranes were evaluated. The results obtained reveal that the produced membranes exhibited a wettability able to provide a moist environment at wound site. Moreover, the membranes' hemocompatibility and fibroblast cell adhesion, spreading and proliferation at the surface of the membranes were also noticed in the in vitro assays. Such results highlight the suitability of these asymmetric membranes for wound dressing applications. | pt |
dc.language.iso | eng | pt |
dc.publisher | MDPI | pt |
dc.relation | SFRH/BD/109563/2015 | pt |
dc.relation | UID/Multi/00709/2013 | pt |
dc.rights | openAccess | pt |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | pt |
dc.subject | electrospinning | pt |
dc.subject | asymmetric membrane | pt |
dc.subject | skin regeneration | pt |
dc.subject | biocompatibility | pt |
dc.title | Photocrosslinkable Nanofibrous Asymmetric Membrane Designed for Wound Dressing | pt |
dc.type | article | - |
degois.publication.firstPage | 653 | pt |
degois.publication.issue | 4 | pt |
degois.publication.title | Polymers | pt |
dc.peerreviewed | yes | pt |
dc.identifier.doi | 10.3390/polym11040653 | pt |
degois.publication.volume | 11 | pt |
dc.date.embargo | 2019-04-10 | * |
uc.date.periodoEmbargo | 0 | pt |
item.fulltext | Com Texto completo | - |
item.grantfulltext | open | - |
item.languageiso639-1 | en | - |
item.cerifentitytype | Publications | - |
item.openairetype | article | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
crisitem.project.grantno | Health Sciences Research Centre | - |
crisitem.author.researchunit | CIEPQPF – Chemical Process Engineering and Forest Products Research Centre | - |
crisitem.author.researchunit | CIEPQPF – Chemical Process Engineering and Forest Products Research Centre | - |
crisitem.author.parentresearchunit | Faculty of Sciences and Technology | - |
crisitem.author.parentresearchunit | Faculty of Sciences and Technology | - |
crisitem.author.orcid | 0000-0002-8943-8329 | - |
crisitem.author.orcid | 0000-0002-1079-3070 | - |
crisitem.author.orcid | 0000-0003-1613-9675 | - |
crisitem.author.orcid | 0000-0003-3393-4427 | - |
Appears in Collections: | I&D CERES - Artigos em Revistas Internacionais |
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File | Description | Size | Format | |
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Photocrosslinkable-nanofibrous-asymmetric-membrane-designed-for-wound-dressingPolymers.pdf | 6.43 MB | Adobe PDF | View/Open |
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