Utilize este identificador para referenciar este registo: https://hdl.handle.net/10316/106938
Título: Near-Wall Flow in Cerebral Aneurysms
Autor: Goodarzi Ardakani, Vahid
Tu, Xin
Gambaruto, Alberto M.
Velho, Iolanda
Tiago, Jorge
Sequeira, Adélia
Pereira, Ricardo 
Palavras-chave: cerebral aneurysm; computational haemodynamics; no-slip critical points; near-wall transport; description of flow field
Data: 2019
Editora: MDPI
Projeto: University of Bristol though Ph.D. scholarships 
UID/Multi/04621/2013 
SFRH/BD/90339/2012 
Título da revista, periódico, livro ou evento: Fluids
Volume: 4
Número: 2
Resumo: The region where the vascular lumen meets the surrounding endothelium cell layer, hence the interface region between haemodynamics and cell tissue, is of primary importance in the physiological functions of the cardiovascular system. The functions include mass transport to/from the blood and tissue, and signalling via mechanotransduction, which are primary functions of the cardiovascular system and abnormalities in these functions are known to affect disease formation and vascular remodelling. This region is denoted by the near-wall region in the present work, and we outline simple yet effective numerical recipes to analyse the near-wall flow field. Computational haemodynamics solutions are presented for six patient specific cerebral aneurysms, at three instances in the cardiac cycle: peak systole, end systole (taken as dicrotic notch) and end diastole. A sensitivity study, based on Newtonian and non-Newtonian rheological models, and different flow rate profiles, is effected for a selection of aneurysm cases. The near-wall flow field is described by the wall shear stress (WSS) and the divergence of wall shear stress (WSSdiv), as descriptors of tangential and normal velocity components, respectively, as well as the wall shear stress critical points. Relations between near-wall and free-stream flow fields are discussed.
URI: https://hdl.handle.net/10316/106938
ISSN: 2311-5521
DOI: 10.3390/fluids4020089
Direitos: openAccess
Aparece nas coleções:FMUC Medicina - Artigos em Revistas Internacionais

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