Please use this identifier to cite or link to this item: https://hdl.handle.net/10316/106354
Title: Effect of Carrageenans on Vegetable Jelly in Humans with Hypercholesterolemia
Authors: Valado, Ana 
Pereira, Maria
Caseiro, Armando 
Figueiredo, João P.
Loureiro, Helena 
Almeida, Carla
Cotas, João 
Pereira, Leonel 
Keywords: carrageenan; TC; HDL-C; LDL-C; TC reduction; TG
Issue Date: 24-Dec-2019
Project: UID/MAR/04292/2019 
Serial title, monograph or event: Marine Drugs
Volume: 18
Issue: 1
Abstract: Changes in lipid profile constitute the main risk factor for cardiovascular diseases. Algae extracted carrageenans are long-chain polysaccharides and their ability to form gels provides for the formation of vegetable jelly. The objective was to evaluate the bioactive potential of carrageenan (E407) in the lipid profile, after ingestion of jelly. A total of 30 volunteers of both sexes, aged 20-64 years and with total cholesterol (TC) values ≥200 mg/dL, who ingested 100 mL/day of jelly for 60 days, were studied. All had two venous blood collections: before starting the jelly intake and after 60 days. At both times, TC, high density lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol (LDL-C) and triglycerides (TG), were evaluated using commercial kits and spectrophotometer. The statistics were performed using the SPSS 25.0 software and p < 0.05 were considered statistically significant. Serum values after 60 days of jelly intake revealed a statistically significant decrease in TC levels (5.3%; p = 0.001) and LDL-C concentration (5.4%; p = 0.048) in females. The daily intake of vegetable jelly for 60 days showed a reduction in serum TC and LDL-C levels in women, allowing us to conclude that carrageenan has bioactive potential in reducing TC concentration.
URI: https://hdl.handle.net/10316/106354
ISSN: 1660-3397
DOI: 10.3390/md18010019
Rights: openAccess
Appears in Collections:I&D MARE - Artigos em Revistas Internacionais

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This item is licensed under a Creative Commons License Creative Commons