Utilize este identificador para referenciar este registo:
https://hdl.handle.net/10316/104747
Título: | Psoriasis: From Pathogenesis to Pharmacological and Nano-Technological-Based Therapeutics | Autor: | Petit, Robert Gironés Cano, Amanda Ortiz, Alba Espina, Marta Prat, Josefina Muñoz, Montserrat Severino, Patrícia Souto, Eliana B. Garcia, Maria L. Pujol, Montserrat Sánchez-López, Elena |
Palavras-chave: | skin inflammatory diseases; psoriasis; psoriasis versus atopic dermatitis; biodegradable nanoparticles; microneedles; clinical trials | Data: | 7-Mai-2021 | Editora: | MDPI AG | Projeto: | UIDB/04469/2020 | Título da revista, periódico, livro ou evento: | International Journal of Molecular Sciences | Volume: | 22 | Número: | 9 | Resumo: | Research in the pathogenesis of inflammatory skin diseases, such as skin dermatitis and psoriasis, has experienced some relevant breakthroughs in recent years. The understanding of age-related factors, gender, and genetic predisposition of these multifactorial diseases has been instrumental for the development of new pharmacological and technological treatment approaches. In this review, we discuss the molecular mechanisms behind the pathological features of psoriasis, also addressing the currently available treatments and novel therapies that are under clinical trials. Innovative therapies developed over the last 10 years have been researched. In this area, advantages of nanotechnological approaches to provide an effective drug concentration in the disease site are highlighted, together with microneedles as innovative candidates for drug delivery systems in psoriasis and other inflammatory chronic skin diseases. | URI: | https://hdl.handle.net/10316/104747 | ISSN: | 1422-0067 | DOI: | 10.3390/ijms22094983 | Direitos: | openAccess |
Aparece nas coleções: | FFUC- Artigos em Revistas Internacionais |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
---|---|---|---|---|
ijms-22-04983-v3.pdf | 1.8 MB | Adobe PDF | Ver/Abrir |
Citações WEB OF SCIENCETM
37
Visto em 2/jul/2024
Visualizações de página
78
Visto em 23/jul/2024
Downloads
26
Visto em 23/jul/2024
Google ScholarTM
Verificar
Altmetric
Altmetric
Este registo está protegido por Licença Creative Commons