Please use this identifier to cite or link to this item: https://hdl.handle.net/10316/101594
Title: Extraction and Analysis of Compounds with Antibacterial Potential from the Red Alga Grateloupia turuturu
Authors: Cardoso, Isabel 
Cotas, João 
Rodrigues, Ana
Ferreira, Daniel
Osório, Nádia 
Pereira, Leonel 
Keywords: Grateloupia turuturu; ethanolic extracts; polysaccharides extract; antibacterial properties; hybrid phycocolloid; polysaccharides characterization
Issue Date: 2019
Project: UID/MAR/04292/2019 
Programme grant SAICTPAC/0019/2015 and Interreg project NASPA 
Serial title, monograph or event: Journal of Marine Science and Engineering
Volume: 7
Issue: 7
Abstract: Nowadays, the development of new drugs only relies on a small number of molecules and 50% of all existent drugs are extracted or synthetically obtained. This work intends to evaluate the antibacterial potential of the ethanolic and polysaccharide extracts obtained from Grateloupia turuturu and to characterize the composition of the alga’s polysaccharides by FTIR-ATR. We used sequential extraction to obtain the extracts that were tested against S. aureus and E. coli. The ethanolic extracts in E. coli, at the highest concentration used (15 mg mL1) showed 45.7% (Tetrasporophyte extract) and 55.1% (Carposporophyte extract) of growth reduction and in S. aureus 56.2% (T extract) and 51.8% (C extract). Polysaccharide extracts started showing significant reduction e ect on E. coli and S. aureus growth at 7.5 mg mL1 with a reduction of 54.9% and 39.5%, respectively. At 15 mg mL1 the reduction observed was 88.5% and 85.4%. The FTIR-ATR allowed to characterize G. turuturu’s polysaccharides concluding that it is composed by a hybrid kappa/iota carrageenan with traces of agar, in both phases of the life cycle. This work allows us to conclude about the antibacterial properties of this alga and the compounds that might be behind this activity, showing that there’s a lot more than a small number of molecules that can be used as natural drugs.
URI: https://hdl.handle.net/10316/101594
ISSN: 2077-1312
DOI: 10.3390/jmse7070220
Rights: openAccess
Appears in Collections:I&D MARE - Artigos em Revistas Internacionais

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