Please use this identifier to cite or link to this item:
https://hdl.handle.net/10316/101507
DC Field | Value | Language |
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dc.contributor.author | Maciel Barbosa, Jorge | - |
dc.contributor.author | Tralhão, José Guilherme | - |
dc.contributor.author | Botelho, Maria Filomena | - |
dc.contributor.author | Nunes Santos, Jorge | - |
dc.contributor.author | Sousa-Pinto, Bernardo | - |
dc.contributor.author | Abrantes, Ana Margarida | - |
dc.contributor.author | Gomes Carrapita, Jorge Humberto | - |
dc.date.accessioned | 2022-08-29T09:45:35Z | - |
dc.date.available | 2022-08-29T09:45:35Z | - |
dc.date.issued | 2020 | - |
dc.identifier.issn | 2559-723X | pt |
dc.identifier.uri | https://hdl.handle.net/10316/101507 | - |
dc.description.abstract | Aim of the study: To systematically review the evidence regarding the association between portal venous pressure (PVP) after hepatectomy and posthepatectomy liver failure (PLHF) or other postsurgical outcomes. Materials and methods: We searched PubMed, Scopus and Web of Science for studies assessing post-hepatectomy PVP (or its variation) and reporting its association with PHLF or other postsurgical outcomes. We performed a random-effects meta-analysis for the association between development of PHLF and post-hepatectomy PVP and its variation. Heterogeneity was assessed using Q-Cochran test and I2 statistic. Quality assessment was performed considering ROBINS-1 Cochrane tool. Results: Four studies, assessing 439 patients, met the eligibility criteria and were included in this systematic review. The meta-analyses, including 3 studies, demonstrated that patients developing PHLF did not have a significantly higher post-hepatectomy PVP when compared to the remainder (1.98; 95%CI=-1.44-5.39; p=0.256; I2=2%), but had a significantly higher PVP variation (increase) during hepatectomy (1.65; 95%CI=1.15-2.15; p<0.001; I2=0%). The quality of the studies allowed to consider the robustness of the conclusions as “median”. Conclusions: An increased PVP variation following hepatectomy associates with a higher risk of PHLF, but the same was not observed for the absolute value of post-hepatectomy PVP. | pt |
dc.language.iso | eng | pt |
dc.rights | openAccess | pt |
dc.rights.uri | http://creativecommons.org/licenses/by-nc/4.0/ | pt |
dc.subject | hepatobiliary surgery | pt |
dc.subject | liver | pt |
dc.subject | portal venous pressure | pt |
dc.subject | portal inflow modulation | pt |
dc.subject | posthepatectomy liver failure | pt |
dc.subject | meta-analysis | pt |
dc.title | Portal Pressure Impact on Clinical Outcome after Major Hepatectomy: A Systematic Review and Meta-Analysis | pt |
dc.type | article | - |
degois.publication.firstPage | 113 | pt |
degois.publication.lastPage | 120 | pt |
degois.publication.issue | 3 | pt |
degois.publication.title | Surgery, Gastroenterology and Oncology | pt |
dc.peerreviewed | yes | pt |
dc.identifier.doi | 10.21614/sgo-25-3-113 | pt |
degois.publication.volume | 25 | pt |
dc.date.embargo | 2020-01-01 | * |
uc.date.periodoEmbargo | 0 | pt |
item.languageiso639-1 | en | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.grantfulltext | open | - |
item.fulltext | Com Texto completo | - |
item.cerifentitytype | Publications | - |
item.openairetype | article | - |
crisitem.author.researchunit | CNC - Center for Neuroscience and Cell Biology | - |
crisitem.author.orcid | 0000-0001-7202-1650 | - |
crisitem.author.orcid | 0000-0003-4185-7871 | - |
Appears in Collections: | FMUC Medicina - Artigos em Revistas Internacionais I&D CIBB - Artigos em Revistas Internacionais I&D ICBR - Artigos em Revistas Internacionais |
Files in This Item:
File | Description | Size | Format | |
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Portal-Pressure-Impact-on-Clinical-Outcome-after-Major-Hepatectomy-A-Systematic-Review-and-MetaAnalysisSurgery-Gastroenterology-and-Oncology.pdf | 1.14 MB | Adobe PDF | View/Open |
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