Project title
This research has been supported by grants fromthe UK Medical Research Council (https://mrc.ukri.org/; G0401310 to MP, the Wellcome Trust (https://wellcome.ac.uk/; 212247Z18Z to MP; 102817A1A to KGS; 208401 to KGS) and The European Union (https://ec. europa.eu/research/fp7/index_en.cfm; HEALTH F2- 2008-200234 to PR and JW and The Netherlands Organisation for Health Research and Development (https://www.zonmw.nl/en/; ZonMw 43200004 to JW)