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https://hdl.handle.net/10316/98759
Title: | Third generation cephalosporin-resistant Klebsiella pneumoniae thriving in patients and in wastewater: what do they have in common? | Authors: | Rocha, Jaqueline Ferreira, Catarina Mil-Homens, Dalila Busquets, Antonio Fialho, Arsénio M Henriques, Isabel Gomila, Margarita Manaia, Célia M. |
Keywords: | Antibiotic resistance; Clinical; Comparative genomics; Klebsiella pneumoniae; Wastewater | Issue Date: | 22-Jan-2022 | Publisher: | BMC | Project: | PTDC/CTA-AMB/28196/2017 UIDB/04565/2020 UIDP/04565/2020 |
Serial title, monograph or event: | BMC Genomics | Volume: | 23 | Issue: | 1 | Abstract: | Klebsiella pneumoniae are ubiquitous bacteria and recognized multidrug-resistant opportunistic pathogens that can be released into the environment, mainly through sewage, where they can survive even after wastewater treatment. A major question is if once released into wastewater, the selection of lineages missing clinically-relevant traits may occur. Wastewater (n = 25) and clinical (n = 34) 3rd generation cephalosporin-resistant K. pneumoniae isolates were compared based on phenotypic, genotypic and genomic analyses. | URI: | https://hdl.handle.net/10316/98759 | ISSN: | 1471-2164 | DOI: | 10.1186/s12864-021-08279-6 | Rights: | openAccess |
Appears in Collections: | FCTUC Ciências da Vida - Artigos em Revistas Internacionais |
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s12864-021-08279-6.pdf | 4.26 MB | Adobe PDF | View/Open |
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