Please use this identifier to cite or link to this item:
https://hdl.handle.net/10316/95079
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Majdi, Amine | - |
dc.contributor.author | Aoudjehane, Lynda | - |
dc.contributor.author | Ratziu, Vlad | - |
dc.contributor.author | Islam, Tawhidul | - |
dc.contributor.author | Afonso, Marta B | - |
dc.contributor.author | Conti, Filomena | - |
dc.contributor.author | Mestiri, Taïeb | - |
dc.contributor.author | Lagouge, Marie | - |
dc.contributor.author | Foufelle, Fabienne | - |
dc.contributor.author | Ballenghien, Florine | - |
dc.contributor.author | Ledent, Tatiana | - |
dc.contributor.author | Moldes, Marthe | - |
dc.contributor.author | Cadoret, Axelle | - |
dc.contributor.author | Fouassier, Laura | - |
dc.contributor.author | Delaunay, Jean-Louis | - |
dc.contributor.author | Aït-Slimane, Tounsia | - |
dc.contributor.author | Courtois, Gilles | - |
dc.contributor.author | Fève, Bruno | - |
dc.contributor.author | Scatton, Olivier | - |
dc.contributor.author | Prip-Buus, Carina | - |
dc.contributor.author | Rodrigues, Cecília M P | - |
dc.contributor.author | Housset, Chantal | - |
dc.contributor.author | Gautheron, Jérémie | - |
dc.date.accessioned | 2021-06-21T11:44:58Z | - |
dc.date.available | 2021-06-21T11:44:58Z | - |
dc.date.issued | 2020-04 | - |
dc.identifier.issn | 01688278 | pt |
dc.identifier.uri | https://hdl.handle.net/10316/95079 | - |
dc.description.abstract | In non-alcoholic fatty liver disease (NAFLD), hepatocytes can undergo necroptosis: a regulated form of necrotic cell death mediated by the receptor-interacting protein kinase (RIPK) 1. Herein, we assessed the potential for RIPK1 and its downstream effector mixed lineage kinase domain-like protein (MLKL) to act as therapeutic targets and markers of activity in NAFLD. | pt |
dc.language.iso | eng | pt |
dc.publisher | Elsevier | pt |
dc.relation | Fondation pour la Recherche Médicale (FRM – ARF20170938613) | pt |
dc.relation | Institute of Cardiometabolism and Nutrition (ICAN – PAP17NECJG) | pt |
dc.relation | Société Francophone du Diabète (SFD – R19114DD) | pt |
dc.relation | Mairie de Paris (Emergences – R18139DD) | pt |
dc.relation | Ministère de l'Enseignement Supérieur et de la Recherche (MESR) | pt |
dc.relation | Fundação para a Ciência e a Tecnologia (PTDC/MED-FAR/ 29097/2017) | pt |
dc.relation | Marie Sklodowska-Curie 722619 grant | pt |
dc.rights | embargoedAccess | pt |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | pt |
dc.subject | MLKL; NAFLD; NASH; Necroptosis; RIPK1; Steatosis | pt |
dc.title | Inhibition of receptor-interacting protein kinase 1 improves experimental non-alcoholic fatty liver disease | pt |
dc.type | article | - |
degois.publication.firstPage | 627-635 | pt |
degois.publication.lastPage | 635 | pt |
degois.publication.issue | 4 | pt |
degois.publication.title | Journal of Hepatology | pt |
dc.relation.publisherversion | https://www.journal-of-hepatology.eu/article/S0168-8278(19)30678-6/fulltext | pt |
dc.peerreviewed | yes | pt |
dc.identifier.doi | 10.1016/j.jhep.2019.11.008 | pt |
degois.publication.volume | 72 | pt |
dc.date.embargo | 2021-04-01 | * |
uc.date.periodoEmbargo | 365 | pt |
item.openairetype | article | - |
item.fulltext | Com Texto completo | - |
item.languageiso639-1 | en | - |
item.grantfulltext | open | - |
item.cerifentitytype | Publications | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
Appears in Collections: | I&D CNC - Artigos em Revistas Internacionais |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
Revised_Manuscript_JHEPAT-D-19-00929.pdf | 306.22 kB | Adobe PDF | View/Open | |
Figures.pdf | 694.43 kB | Adobe PDF | View/Open |
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