Please use this identifier to cite or link to this item: http://hdl.handle.net/10316/84853
Title: Medical Toxicology of Drugs of Abuse
Authors: Cunha-Oliveira, Teresa 
Rego, Ana Cristina 
Carvalho, Félix 
Oliveira, Catarina R. 
Issue Date: 2013
Serial title, monograph or event: Principles of Addiction - Comprehensive Addictive Behaviors and Disorders
Volume: 1
Abstract: This chapter describes the toxicological properties of the main drugs of abuse, namely alcohol, amphetamines, cocaine, heroin, and cannabis. All these drugs share chemical similarities with neuronal endogenous compounds and are thus psychoactive. Besides the nervous system, drugs of abuse affect other body systems, inducing cardiovascular, metabolic, hepatic, renal, respiratory, reproductive, and immune impairments, explaining the medical complications observed in drug addicts. The fact that the toxicity of these drugs may be affected by the interactions with other substances, namely on polydrug abuse and street drug adulteration, is also highlighted. A comparative view of the medical toxicological effects as well as the pharmacokinetic and pharmacodynamic characteristics of these drugs of abuse are presented.
URI: http://hdl.handle.net/10316/84853
ISBN: 9780123983367
DOI: 10.1016/B978-0-12-398336-7.00017-6
Rights: openAccess
Appears in Collections:I&D CNC - Capítulos (ou partes) de Livros

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